Uitslagenmatrix
| ADO | AJA | AZ | EMM | FEY | FOR | GRO | HEE | HER | PEC | PSV | RKC | SPA | TWE | UTR | VIT | VVV | WIL | |
| ADO Den Haag | * | |||||||||||||||||
| Ajax | * | |||||||||||||||||
| AZ | * | |||||||||||||||||
| FC Emmen | * | |||||||||||||||||
| Feyenoord | * | |||||||||||||||||
| Fortuna Sittard | * | |||||||||||||||||
| FC Groningen | * | |||||||||||||||||
| sc Heerenveen | * | |||||||||||||||||
| Heracles Almelo | * | |||||||||||||||||
| PEC Zwolle | * | |||||||||||||||||
| PSV | * | |||||||||||||||||
| RKC Waalwijk | * | |||||||||||||||||
| Sparta Rotterdam | * | |||||||||||||||||
| FC Twente | * | |||||||||||||||||
| FC Utrecht | * | |||||||||||||||||
| Vitesse | * | |||||||||||||||||
| VVV-Venlo | * | |||||||||||||||||
| Willem II | * |
Wedstrijden
Het seizoen 2019-2020 is een historisch seizoen geworden. Niet vanwege een bijzonder sportief verloop of een verrassende kampioen, maar omdat het niet is afgemaakt. Door het oprukkende coronavirus wordt het voetbal op 13 maart abrupt stilgelegd. Aanvankelijk nog in de hoop dat de jaargang afgemaakt kan worden, desnoods in juni of juli of zonder publiek, maar op 21 april is het besluit daar: het kabinet besluit dat er tot 1 september geen evenementen plaatsvinden en wedstrijden in het betaald voetbal vallen hieronder.
De KNVB besluit het seizoen te schappen: dus geen kampioen, geen degradanten en promovendi. De Europese tickets worden verdeeld aan de hand van de ranglijst op het moment van stoppen. Voor het eerst sinds 1945 is er daarom geen landskampioen en voor het eerst sinds 1954 haalt een competitie het einde niet. Al werd dat toen gevolgd door een nieuwe competitie.
Het zorgt voor een onbevredigend einde van een seizoen waarin Ajax lange tijd dominant is, maar de Amsterdammers beginnen vanaf december te kwakkelen en zien AZ in punten gelijk komen. Feyenoord begint na een zwak begin onder de nieuwe trainer Jaap Stam met de tussentijds aangestelde eeuwig jonge Dick Advocaat aan een ware opmars. PSV zet Mark van Bommel na een slechte fase aan de kant, maar komt ook daarna maar moeizaam op gang.
ADO Den Haag en RKC Waalwijk ontspringen de degradatiedans door het stopzetten van de competitie. Voor het eerst sinds lange tijd zijn er weer twee rechtstreekse degradatieplaatsen en die lijken na 26 duels al vrijwel zeker verdeeld, maar in Den Haag en Waalwijk hebben ze geluk.
Vooral FC Utrecht voelt zich tekort gedaan. De club haalt de (niet gespeelde) bekerfinale tegen Feyenoord en staat nipt achter Willem II (met een wedstrijd minder gespeeld), maar grijpt toch naast een Europees ticket.
Wedstrijdenmatrix
| ADO | AJA | AZ | EMM | FEY | FOR | GRO | HEE | HER | PEC | PSV | RKC | SPA | TWE | UTR | VIT | VVV | WIL | |
| ADO Den Haag | * | 0-2 | 0-1 | 1-1 | 1-1 | 0-0 | 0-3 | 2-0 | 1-2 | 0-0 | 2-4 | 0-0 | 1-0 | 3-3 | ||||
| Ajax | 6-1 | * | 0-2 | 5-0 | 4-0 | 5-0 | 2-0 | 4-1 | 4-1 | 1-0 | 3-0 | 2-1 | 4-0 | 0-2 | ||||
| AZ | 4-0 | 1-0 | * | 3-0 | 4-0 | 0-0 | 2-4 | 2-0 | 2-0 | 4-0 | 5-1 | 3-0 | 1-0 | 1-3 | ||||
| FC Emmen | 3-0 | * | 3-3 | 2-1 | 0-1 | 2-0 | 1-0 | 1-3 | 1-1 | 2-0 | 2-0 | 2-1 | 3-0 | 4-2 | ||||
| Feyenoord | 3-2 | 0-3 | 3-0 | * | 2-1 | 3-1 | 1-1 | 1-0 | 3-1 | 3-2 | 2-2 | 5-1 | 1-1 | 2-0 | ||||
| Fortuna Sittard | 1-0 | 0-0 | 4-2 | * | 1-0 | 2-1 | 1-1 | 1-1 | 3-2 | 0-0 | 2-3 | 1-3 | 4-1 | 2-3 | ||||
| FC Groningen | 2-1 | 2-0 | 1-1 | * | 1-2 | 2-0 | 0-1 | 3-0 | 2-0 | 1-3 | 0-1 | 1-0 | 0-1 | 2-0 | ||||
| sc Heerenveen | 2-2 | 1-3 | 1-2 | 1-1 | 1-1 | 1-1 | * | 1-1 | 1-0 | 2-1 | 0-0 | 1-1 | 3-2 | 1-1 | 1-2 | |||
| Heracles Almelo | 4-0 | 1-0 | 2-0 | 2-3 | 2-0 | 0-1 | * | 4-0 | 0-2 | 4-2 | 1-3 | 1-1 | 6-1 | 4-1 | ||||
| PEC Zwolle | 3-1 | 2-4 | 0-3 | 3-4 | 3-1 | 1-0 | * | 0-4 | 6-2 | 2-2 | 3-3 | 4-3 | 1-3 | |||||
| PSV | 3-1 | 1-1 | 0-4 | 1-1 | 5-0 | 3-1 | 2-1 | 4-1 | * | 1-1 | 5-0 | 4-1 | 3-0 | |||||
| RKC Waalwijk | 0-3 | 1-2 | 0-2 | 1-1 | 1-3 | 2-0 | 0-0 | 1-3 | * | 0-1 | 3-0 | 2-1 | 1-2 | 1-2 | ||||
| Sparta Rotterdam | 4-2 | 1-4 | 3-0 | 5-1 | 1-1 | 1-2 | 0-0 | 2-2 | 4-0 | * | 2-1 | 1-2 | 2-0 | 4-1 | ||||
| FC Twente | 2-5 | 2-0 | 4-1 | 0-0 | 2-3 | 2-3 | 2-1 | 1-1 | 3-3 | 2-0 | * | 3-1 | 0-3 | 0-1 | ||||
| FC Utrecht | 4-0 | 0-3 | 3-1 | 1-2 | 6-0 | 3-1 | 3-0 | 0-1 | 5-1 | 2-1 | * | 1-2 | 2-0 | |||||
| Vitesse | 0-2 | 2-2 | 2-1 | 1-1 | 0-0 | 4-2 | 1-2 | 4-2 | 3-0 | 1-2 | 1-0 | 2-1 | * | 3-0 | ||||
| VVV-Venlo | 1-4 | 2-0 | 0-3 | 0-0 | 2-1 | 0-3 | 1-0 | 1-2 | 1-1 | 3-1 | 2-1 | 1-1 | 0-4 | * | ||||
| Willem II | 1-1 | 2-1 | 0-1 | 0-0 | 3-1 | 1-0 | 0-0 | 2-1 | 2-1 | 4-0 | 1-1 | 0-2 | 1-0 | * |
Stand bij beëindigen competitie
| 1 | Ajax ** | 25 | 18 | 2 | 5 | 56 | 68 | 23 | +45 | 53.056 |
| 2 | AZ ** | 25 | 18 | 2 | 5 | 56 | 54 | 17 | +37 | 10.926 |
| 3 | Feyenoord *** | 25 | 14 | 8 | 3 | 50 | 50 | 35 | +15 | 42.210 |
| 4 | PSV *** | 26 | 14 | 7 | 5 | 49 | 54 | 28 | +26 | 33.625 |
| 5 | Willem II *** | 26 | 13 | 5 | 8 | 44 | 37 | 34 | +3 | 13.578 |
| 6 | FC Utrecht | 25 | 12 | 5 | 8 | 41 | 50 | 34 | +16 | 19.437 |
| 7 | Vitesse | 26 | 12 | 5 | 9 | 41 | 45 | 35 | +10 | 14.571 |
| 8 | Heracles Almelo | 26 | 10 | 6 | 10 | 36 | 40 | 34 | +6 | 10.307 |
| 9 | FC Groningen | 26 | 10 | 5 | 11 | 35 | 27 | 26 | +1 | 19.509 |
| 10 | sc Heerenveen | 26 | 8 | 9 | 9 | 33 | 41 | 41 | 0 | 18.489 |
| 11 | Sparta Rotterdam | 26 | 9 | 6 | 11 | 33 | 41 | 45 | -4 | 10.048 |
| 12 | FC Emmen | 26 | 9 | 5 | 12 | 32 | 32 | 45 | -13 | 8.240 |
| 13 | VVV-Venlo | 26 | 8 | 4 | 14 | 28 | 24 | 51 | -27 | 6.579 |
| 14 | FC Twente | 26 | 7 | 6 | 13 | 27 | 34 | 46 | -12 | 27.107 |
| 15 | PEC Zwolle | 26 | 7 | 5 | 14 | 26 | 37 | 55 | -18 | 13.357 |
| 16 | Fortuna Sittard | 26 | 6 | 8 | 12 | 26 | 29 | 52 | -23 | 7.975 |
| 17 | ADO Den Haag | 26 | 4 | 7 | 15 | 19 | 25 | 54 | -29 | 12.001 |
| 18 | RKC Waalwijk | 26 | 4 | 3 | 19 | 15 | 27 | 60 | -33 | 5.689 |
Wedstrijden
| R | Datum: | Thuis: | Uit: | Sc: | Ts.: | Ar: | Details: |
|---|---|---|---|---|---|---|---|
| 1 | 02/08/2019 | PEC Zwolle | Willem II | 1-3 | 13.824 | Manschot | 1-0 Thy, 1-1 Pavlidis, 1-2 Leemans (e.d.), 1-3 Pavlidis |
| 1 | 03/08/2019 | Vitesse | Ajax | 2-2 | 18.100 | Nijhuis | 1-0 Bero, 1-1 Van de Beek, 2-1 Bazoer, 2-2 Tadic; R: Bazoer |
| 1 | 03/08/2019 | FC Emmen | FC Groningen | 0-1 | 8.245 | Van Boekel | 0-1 Hrustic |
| 1 | 03/08/2019 | VVV-Venlo | RKC Waalwijk | 3-1 | 5.560 | Kooij | 0-1 Delcroix, 1-1 Soriano, 2-1 Opoku (pen), 3-1 Van Ooijen |
| 1 | 03/08/2019 | FC Twente | PSV | 1-1 | 27.200 | Gözübüyük | 1-0 Nakamura, 1-1 Dumfries |
| 1 | 04/08/2019 | Heracles Almelo | sc Heerenveen | 0-4 | 9.640 | Martens | 0-1 Dresevic, 0-2 Bruijn, 0-3 Van Bergen, 0-4 Ejuke |
| 1 | 04/08/2019 | ADO Den Haag | FC Utrecht | 2-4 | 10.633 | Blom | 1-0 Meijers, 2-0 Falkenburg, 2-1 Zwinkels (e.d.), 2-2 Kerk, 2-3 Immers (e.d.), 2-4 Venema |
| 1 | 04/08/2019 | Feyenoord | Sparta Rotterdam | 2-2 | 41.000 | Makkelie | 0-1 Rayhi, 1-1 Berghuis, 1-2 Veldwijk, 2-2 Larsson |
| 1 | 04/08/2019 | AZ | Fortuna Sittard | 4-0 | 12.858 | Higler | 1-0 Vlaar, 2-0 Idrissi, 3-0 Boadu, 4-0 Sugawara |
| 2 | 09/08/2019 | Sparta Rotterdam | VVV-Venlo | 4-1 | 10.012 | Nijhuis | 0-1 Van Ooijen, 1-1 Dervisoglu, 2-1 Ache, 3-1 Harroui, 4-1 Veldwijk |
| 2 | 10/08/2019 | FC Groningen | FC Twente | 1-3 | 17.500 | Bax | 0-1 Nakamura, 0-2 Cantalapiedra, 1-2 Doan, 1-3 Vuckic; R: Lundqvist, Te Wierik (Gro) |
| 2 | 10/08/2019 | Ajax | FC Emmen | 5-0 | 52.000 | Gözübüyük | 1-0 Van de Beek, 2-0 Ziyech, 3-0 Tadic, 4-0 en 5-0 Huntelaar, |
| 2 | 10/08/2019 | PSV | ADO Den Haag | 3-1 | 32.000 | Makkelie | 0-1 Necid, 1-1 Bruma, 2-1 Malen, 3-1 Gakpo |
| 2 | 10/08/2019 | Willem II | Vitesse | 0-2 | 12.825 | Van de Graaf | 0-1 Grot, 0-2 Matavz |
| 2 | 11/08/2019 | Fortuna Sittard | Heracles Almelo | 1-1 | 5.866 | Blom | 0-1 Van de Water, 1-1 Diemers (pen) |
| 2 | 11/08/2019 | sc Heerenveen | Feyenoord | 1-1 | 18.600 | Kamphuis | 0-1 Berghuis (pen), 1-1 Dresevic |
| 2 | 11/08/2019 | RKC Waalwijk | AZ | 0-2 | 6.023 | Lindhout | 0-1 en 0-2 Idrissi; R: Gaari (RKC) |
| 2 | 11/08/2019 | FC Utrecht | PEC Zwolle | 3-1 | 18.736 | Mulder | 0-1 Hamer, 1-1 Van de Streek, 2-1 Gustafson (pen), 3-1 Janssen |
| 3 | 16/08/2019 | Vitesse | PEC Zwolle | 3-0 | 12.273 | Dieperink | 1-0 Matavz (pen), 2-0 Karavaev, 3-0 Linssen |
| 3 | 17/08/2019 | ADO Den Haag | Sparta Rotterdam | 1-2 | 12.479 | Higler | 0-1 en 0-2 Rayhi, 1-2 Immers |
| 3 | 17/08/2019 | VVV-Venlo | Ajax | 1-4 | 8.000 | Makkelie | 0-1 Ziyech, 0-2 Tadic (pen), 0-3 Huntelaar, 0-4 Neres, 1-4 Linthorst |
| 3 | 17/08/2019 | FC Emmen | sc Heerenveen | 2-0 | 8.145 | Nijhuis | 1-0 Laursen, 2-0 Bijl |
| 3 | 18/08/2019 | Heracles Almelo | PSV | 0-2 | 10.063 | Kamphuis | 0-1 Bergwijn, 0-2 Ihattaren |
| 3 | 18/08/2019 | Fortuna Sittard | Willem II | 2-3 | 7.273 | Lindhout | 1-0 Damascan, 1- Vrousai, 1-2 (pen) en 1-3 Pavlidis, 2-3 Damascan |
| 3 | 18/08/2019 | Feyenoord | FC Utrecht | 1-1 | 37.500 | Van Boekel | 0-1 Abass, 1-1 Haps |
| 3 | 18/08/2019 | FC Twente | RKC Waalwijk | 3-3 | 25.700 | Perez | 0-1 Tahiri, 1-1 Vuckic, 1-2 Van Weert, 2-2 Vuckic, 3-2 Zekhnini, 3-3 Quasten |
| 3 | 18/08/2019 | AZ | FC Groningen | 0-0 | 8.563 | Gözübüyük | (Gespeeld in Den Haag) |
| 4 | 24/08/2019 | Willem II | FC Emmen | 2-1 | 13.300 | Mulder | 1-0 Köhlert, 1-1 Kolar (pen), 2-1 Köhlert |
| 4 | 24/08/2019 | Heracles Almelo | Vitesse | 1-1 | 9.344 | Manschot | 0-1 Linssen, 1-1 Dessers |
| 4 | 24/08/2019 | sc Heerenveen | FC Twente | 0-0 | 16.328 | Van Boekel | |
| 4 | 25/08/2019 | RKC Waalwijk | ADO Den Haag | 0-3 | 5.034 | Vd Graaf | 0-1 Beugelsdijk, 0-2 en 0-3 (pen) Necid R: Bakker (ADO) |
| 4 | 25/08/2019 | FC Utrecht | VVV-Venlo | 1-2 | 17.986 | Kamphuis | 0-1 en 0-2 Linthorst, 1-2 Dalmau |
| 4 | 25/08/2019 | PEC Zwolle | Sparta Rotterdam | 2-2 | 12.532 | Gözübüyük | 0-1 Ache, 1-1 Bel Hassani, 2-1 Thy, 2-2 Veldwijk |
| 5 | 30/08/2019 | FC Emmen | PEC Zwolle | 1-3 | 8.293 | Vd Kerkhof | 1-0 Bakker, 1-1 Johnsen, 1-2 Bruns, 1-3 Bel Hassani |
| 5 | 31/08/2019 | sc Heerenveen | Fortuna Sittard | 1-1 | 15.128 | Vd Graaf | 0-1 Passlack, 1-1 Odgaard (pen) |
| 5 | 31/08/2019 | FC Groningen | Heracles Almelo | 1-2 | 15.934 | Lindhout | 0-1 Van de Water, 1-1 Warmerdam, 1-2 Czyborra |
| 5 | 31/08/2019 | ADO Den Haag | VVV-Venlo | 1-0 | 10.617 | Mulder | 1-0 Pinas; R: Post (VVV) |
| 5 | 01/09/2019 | FC Twente | FC Utrecht | 3-1 | 25.500 | Manschot | 1-0 Aitor (pen), 1-1 Dalmau, 2-1 Vuckic, 3-1 Aitor (pen); R: Guwara (Utr) |
| 5 | 01/09/2019 | RKC Waalwijk | PSV | 1-3 | 7.035 | Blom | 1-0 Meulensteen, 1-1 Quasten (e.d.), 1-2 Baumgartl,1-3 Mitroglu |
| 5 | 01/09/2019 | Sparta Rotterdam | Ajax | 1-4 | 10.599 | Kamphuis | 0-1 Promes, 0-2 Ziyech, 0-3 Tadic (pen), 0-4 Ziyech, 1-4 Dervisoglu |
| 5 | 01/09/2019 | Willem II | Feyenoord | 0-1 | 13.875 | Nijhuis | 0-1 Berghuis (pen) |
| 5 | 01/09/2019 | Vitesse | AZ | 2-1 | 13.290 | Higler | 0-1 Koopmeiners (pen), 1-1 Matavz, 2-1 Bero (pen) |
| 6 | 14/09/2019 | AZ | Sparta Rotterdam | 5-1 | 8.000 | Makkelie | 0-1 Harroui, 1-1 Idrissi, 2-1 en 3-1 Boadu, 4-1 Idrissi, 5-1 Koopmeiners (pen) (Gespeeld in Den Haag) |
| 6 | 14/09/2019 | PSV | Vitesse | 5-0 | 33.300 | Van Boekel | 1-0, 2-0, 3-0, 4-0 (pen) en 5-0 (pen) Malen |
| 6 | 14/09/2019 | VVV-Venlo | FC Groningen | 2-1 | 6.265 | Vd Kerkhof | 1-0 Yeboah, 1-1 Hrustic, 2-1 Linthorst |
| 6 | 14/09/2019 | Ajax | sc Heerenveen | 4-1 | 52.000 | Lindhout | 1-0 Tadic, 1-1 Odgaard, 2-1 Tagliafico, 3-1 Schuurs, 4-1 Tagliafico |
| 6 | 14/09/2019 | FC Utrecht | FC Emmen | 3-1 | 17.661 | Dieperink | 1-0 Dalmau, 2-0 Kerk, 2-1 De Leeuw, 3-1 Bahebeck |
| 6 | 15/09/2019 | PEC Zwolle | RKC Waalwijk | 6-2 | 13.028 | Manschot | 1-0 Bel Hassani, 1-1 Meulensteen, 1-2 Leemans, 2-2, 3-2, 4-2 en 5-2 Ghoochannejhad, 6-2 Hamer |
| 6 | 15/09/2019 | Feyenoord | ADO Den Haag | 3-2 | 40.000 | Gözübüyük | 1-0 Karsdorp (pen), 2-0 Narsingh, 3-0 Fer (pen), 3-1 Ié (e.d.), 5-2 Tapia (e.d.) |
| 6 | 15/09/2019 | Heracles Almelo | Willem II | 4-1 | 11.254 | Kooij | 1-0 Dessers, 1-1 Pavlidis, 2-1 Dessers, 3-1 Van de Water, 4-1 Mauro Junior |
| 6 | 15/09/2019 | Fortuna Sittard | FC Twente | 2-3 | 7.377 | Higler | 0-1 Nakamura, 0-2 Espinosa, 0-23 Aburjana, 1-3 Vuckic (e.d.), 2-3 Ciss |
| 7 | 20/09/2019 | FC Twente | Heracles Almelo | 2-3 | 29.300 | Kamphuis | 1-0 Aitor, 1-1 Dessers, 1-2 en 1-3 Mauro Junior, 2-3 Berggreen |
| 7 | 21/09/2019 | Sparta Rotterdam | RKC Waalwijk | 4-0 | 10.231 | Bax | 1-0 Smeets, 2-0 Ache, 3-0 Dervisoglu, 4-0 Rayhi |
| 7 | 21/09/2019 | FC Groningen | PEC Zwolle | 2-0 | 16.471 | Vd Eijk | 1-0 Lundqvist, 2-0 Hrustic |
| 7 | 21/09/2019 | Willem II | VVV-Venlo | 1-0 | 13.227 | Dieperink | 1-0 Pavlidis |
| 7 | 21/09/2019 | Vitesse | Fortuna Sittard | 4-2 | 20.800 | Kooij | 0-1 Diemers, 1-1 Matavz, 1-2 Angha, 2-2 en 3-2 Linssen, 4-2 Bero |
| 7 | 22/09/2019 | ADO Den Haag | AZ | 0-1 | 12.091 | Lindhout | 0-1 Koopmeiners (pen) |
| 7 | 22/09/2019 | sc Heerenveen | FC Utrecht | 1-1 | 16.593 | Mulder | 0-1 Kerk, 1-1 Ejuke |
| 7 | 22/09/2019 | PSV | Ajax | 1-1 | 35.000 | Makkelie | 0-1 Promes, 1-1 Malen |
| 7 | 22/09/2019 | FC Emmen | Feyenoord | 3-3 | 8.309 | Higler | 0-1 Kökcü, 0-2 Narsingh, 1-2 De Vos, 2-2 Peña, 3-2 Slagveer, 3-3 Toornstra; R: Heylen (Emm) |
| 4 | 25/09/2019 | Ajax | Fortuna Sittard | 5-0 | 53.000 | Manschot | 1-0 Promes, 2-0 Neres, 3-0 Promes, 4-0 Harries (e.d.), 5-0 Promes |
| 4 | 25/09/2019 | PSV | FC Groningen | 3-1 | 32.800 | Nijhuis | 1-0 Rosario, 2-0 Dumfries, 2-1 Lundqvist, 3-1 Bruma |
| 4 | 26/09/2019 | Feyenoord | AZ | 0-3 | 35.000 | Kamphuis | 0-1 Boadu, 0-2 Stengs, 0-3 Idrissi |
| 8 | 27/09/2019 | FC Emmen | ADO Den Haag | 3-0 | 8.002 | Blank | 1-0 Goossens (e.d.), 2-0 De Leeuw, 3-0 Slagveer |
| 8 | 28/09/2019 | VVV-Venlo | sc Heerenveen | 0-3 | 5.944 | Gözübüyük | 0-1 en 0-2 Ejuke, 0-3 Odgaard |
| 8 | 28/09/2019 | Ajax | FC Groningen | 2-0 | 53.000 | Kuipers | 1-0 Martinez, 2-0 Huntelaar; R: Warmerdam (Gro) |
| 8 | 28/09/2019 | Fortuna Sittard | Sparta Rotterdam | 0-0 | 7.483 | Martens | R: Auassar (Spa) |
| 8 | 29/09/2019 | AZ | Heracles Almelo | 2-0 | 7.241 | Van Boekel | 1-0 Koopmeiners (pen), 2-0 Stengs (Gespeeld in Den Haag) |
| 8 | 29/09/2019 | PEC Zwolle | PSV | 0-4 | 13.482 | Higler | 0-1 Rosario, 0-2 Malen, 0-3 Doan, 0-4 Gutierrez |
| 8 | 29/09/2019 | Feyenoord | FC Twente | 5-1 | 32.500 | Makkelie | 1-0 Berghuis, 1-1 Aitor, 2-1 Larsson, 3-1 Bijen (ed), 4-1 Sinisterra, 5-1 Larsson |
| 8 | 29/09/2019 | FC Utrecht | Willem II | 2-0 | 19.419 | Vd Graaf | 1-0 Janssen, 2-0 Kerk; R: Guwara (Utr) |
| 8 | 29/09/2019 | RKC Waalwijk | Vitesse | 1-2 | 4.858 | Nijhuis | 0-1 Dicko, 1-1 Leemans (pen), 1-2 Tannane (pen) R: Lelieveld (Vit) |
| 9 | 04/10/2019 | FC Groningen | RKC Waalwijk | 3-0 | 16.029 | Kooij | 1-0 Te Wieik, 2-0 Benschop, 3-0 Gudmundsson |
| 9 | 05/10/2019 | Heracles Almelo | FC Emmen | 2-0 | 10.376 | Vd Eijk | 1-0 Dessers, 2-0 Veendorp (e.d.) |
| 9 | 06/10/2019 | PSV | VVV-Venlo | 4-1 | 33.000 | Lindhout | 1-0 Bergwijn, 2-0 Dumfries, 3-0 Malen, 3-1 Pachnik, 4-1 Malen |
| 9 | 05/10/2019 | Sparta Rotterdam | FC Twente | 2-1 | 10.435 | Manschot | 1-0 Dervisoglu, 1-1 Verdonk, 2-1 Smeets R: Pleguezuelo (Twe) |
| 9 | 05/10/2019 | sc Heerenveen | PEC Zwolle | 1-0 | 16.632 | Makkelie | 1-0 Van Bergen |
| 9 | 06/10/2019 | ADO Den Haag | Ajax | 0-2 | 14.733 | Blom | 0-1 Huntelaar, 0-2 Neres |
| 9 | 06/10/2019 | Fortuna Sittard | Feyenoord | 4-2 | 8.511 | Van Boekel | 1-0 Ciss, 1-1 Haps, 2-1 Ciss, 3-1 Harries, 4-1 Sambou, 4-2 Berghuis |
| 9 | 05/10/2019 | Vitesse | FC Utrecht | 2-1 | 12.704 | Kuipers | 1-0 Clark, 1-1 Maher, 2-1 Matavz |
| 9 | 06/10/2019 | Willem II | AZ | 1-1 | 12.707 | Higler | 0-1 Koopmeiners (pen), 1-1 Köhlert; R: Boadu (AZ) |
| 10 | 19/10/2019 | AZ | sc Heerenveen | 2-4 | 7.648 | Kuipers | 0-1 Botman, 1-1 Vlaar, 1-2 Kongolo, 1-3 Odgaard, 2-3 Stengs, 2-4 Koopmeiners (e.d.) |
| 10 | 19/10/2019 | FC Utrecht | PSV | 3-0 | 22.632 | Makkelie | 1-0 Van de Streek, 2-0 Maher, 3-0 Klaiber R: Viergever, Hendrix (PSV) |
| 10 | 19/10/2019 | VVV-Venlo | Vitesse | 0-4 | 5.992 | Mulder | 0-1 en 0-2 Linssen, 0-3 Bazoer, 0-4 Dicko |
| 10 | 19/10/2019 | FC Twente | Willem II | 0-1 | 27.500 | Vd Kerkhof | 0-1 Vrousai |
| 10 | 19/10/2019 | RKC Waalwijk | Ajax | 1-2 | 7.508 | Lindhout | 0-1 Tadic, 1-1 Bakari, 1-2 Promes |
| 10 | 20/10/2019 | Feyenoord | Heracles Almelo | 1-1 | 37.000 | Manschot | 1-0 Toornstra, 1-1 Kiomourtzoglu |
| 10 | 20/10/2019 | FC Emmen | Fortuna Sittard | 2-1 | 8.130 | Nijhuis | 0-1 Sambou, 1-1 De Leeuw, 2-1 Peña |
| 10 | 20/10/2019 | PEC Zwolle | ADO Den Haag | 3-1 | 12.943 | Gözübüyük | 0-1 Kramer, 1-1 Bel Hassani, 2-1 Ghoochannejhad, 3-1 Clement |
| 10 | 20/10/2019 | FC Groningen | Sparta Rotterdam | 2-0 | 17.582 | Blom | 1-0 Sierhuis, 2-0 Benschop; R: Coremans (Spa) |
| 11 | 25/10/2019 | FC Twente | FC Emmen | 4-1 | 27.000 | Bax | 1-0 en 2-0 Vickic, 3-0 Selahi, 3-1 Veendorp, 3-1 Aitor (pen) |
| 11 | 26/10/2019 | Willem II | RKC Waalwijk | 2-1 | 13.877 | Blom | 1-0 Heerkens, 2-0 Llonch, 2-1 Elbers |
| 11 | 26/10/2019 | Fortuna Sittard | VVV-Venlo | 4-1 | 8.388 | Makkelie | 1-0 en 2-0 Diemers, 3-0 Ciss, 3-1 Opoku, 4-1 Diemers (pen) |
| 11 | 26/10/2019 | Vitesse | ADO Den Haag | 0-2 | 12.663 | Manschot | 0-1 Summerville, 0-2 Immers |
| 11 | 26/10/2019 | Heracles Almelo | PEC Zwolle | 4-0 | 10.157 | Perez | 1-0 Czyborra, 2-0 Van de Water, 3-0 Mauro Junior, 4-0 Konings |
| 11 | 27/10/2019 | sc Heerenveen | FC Groningen | 1-1 | 22.428 | Lindhout | 1-0 Faik (pen), 1-1 Benschop (pen) |
| 11 | 27/10/2019 | PSV | AZ | 0-4 | 34.000 | Van Boekel | 0-1 en 0-2 Boadu, 0-3 Svensson, 0-4 De Wit R: Thomas (PSV) |
| 11 | 27/10/2019 | Sparta Rotterdam | FC Utrecht | 1-2 | 10.332 | Vd Eijk | 0-1 Bahebeck (pen), 1-1 Ache, 1-2 Maher (pen) |
| 11 | 27/10/2019 | Ajax | Feyenoord | 4-0 | 53.968 | Gözübüyük | 1-0 Ziyech, 2-0 Tagliafico, 3-0 Neres, 4-0 Van de Beek |
| 12 | 01/11/2019 | PEC Zwolle | Ajax | 2-4 | 14.000 | Kuipers | 0-1 en 0-2 Promes, 0-3 Neres, 1-3 Hamer, 2-3 Saymak, 2-4 Neres |
| 12 | 02/11/2019 | Sparta Rotterdam | PSV | 2-2 | 10.387 | Nijhuis | 1-0 Ache, 1-1 Sadilek, 2-1 Rayhi, 2-2 Gakpo |
| 12 | 02/11/2019 | RKC Waalwijk | Heracles Almelo | 2-0 | 4.689 | Vd Graaf | 1-0 Sow, 2-0 Vermeulen |
| 12 | 02/11/2019 | AZ | FC Twente | 3-0 | 7.579 | Makkelie | 1-0 Hatzidiakos, 2-0 De Wit, 3-0 Boadu R: Drommel (Twe); (Gespeeld in Den Haag) |
| 12 | 03/11/2019 | FC Utrecht | Fortuna Sittard | 6-0 | 18.776 | Kamphuis | 1-0 Kerk, 2-0 Van de Streek, 3-0 Gustafson (pen), 4-0 Van de Streek, 5-0 Gustafson (pen), 6-0 Makienok |
| 12 | 03/11/2019 | FC Emmen | Vitesse | 2-1 | 8.048 | Kooij | 1-0 De Leeuw, 2-0 Laursen, 2-1 Dicko |
| 12 | 03/11/2019 | ADO Den Haag | sc Heerenveen | 1-1 | 12.681 | Vd Eijk | 1-0 Kramer (pen), 1-1 Botman |
| 12 | 03/11/2019 | VVV-Venlo | Feyenoord | 0-3 | 6.572 | Blom | 0-1 Jørgensen, 0-2 en 0-3 (pen) Berghuis R: Kum (VVV) |
| 12 | 03/11/2019 | FC Groningen | Willem II | 2-0 | 16.590 | Van Boekel | 1-0 en 2-0 Sierhuis |
| 13 | 08/11/2019 | Vitesse | FC Groningen | 1-2 | 12.590 | Gözübüyük | 0-1 en 0-2 Asoro, 1-2 Linssen |
| 13 | 09/11/2019 | sc Heerenveen | Sparta Rotterdam | 2-1 | 18.089 | Kooij | 0-1 en 0-2 Ejuke, 1-2 Veldwijk |
| 13 | 09/11/2019 | Fortuna Sittard | ADO Den Haag | 1-0 | 8.223 | Vd Kerkhof | 1-0 Ciss |
| 13 | 09/11/2019 | Heracles Almelo | VVV-Venlo | 6-1 | 9.400 | Kamphuis | 1-0 Merkel, 2-0 Van de Water, 3-0 Dessers, 4-0 Mauro Junior, 5-0 Dessers, 5-1 Van Ooijen, 6-1 Dessers |
| 13 | 10/11/2019 | Willem II | PSV | 2-1 | 14.400 | Kuipers | 1-0 en 2-0 Nunnely, 2-1 Pereiro |
| 13 | 10/11/2019 | FC Twente | PEC Zwolle | 2-1 | 26.900 | Blom | 1-0 Vickic, 2-0 Latibeaudiere, 2-1 Ghoochannejhad |
| 13 | 10/11/2019 | Ajax | FC Utrecht | 4-0 | 53.000 | Nijhuis | 1-0 Van de Beek, 2-0 Tadic, 3-0 Van de Beek, 4-0 Martinez |
| 13 | 10/11/2019 | AZ | FC Emmen | 3-0 | 5.565 | Mulder | 1-0 Koopmeiners (pen), 2-0 Boadu, 3-0 Stengs (Gespeeld in Den Haag) |
| 13 | 10/11/2019 | Feyenoord | RKC Waalwijk | 3-2 | 47.000 | Makkelie | 0-1 Maatsen, 0-2 Sow, 1-2 Jørgensen, 2-2 Larsson, 3-2 Senesi; R: Speirings (RKC) |
| 14 | 23/11/2019 | FC Utrecht | AZ | 0-3 | 22.401 | Kuipers | 0-1 Koopmeiners, 0-2 Idrissi, 0-3 Boadu |
| 14 | 23/11/2019 | PEC Zwolle | Fortuna Sittard | 3-1 | 13.912 | Kooij | 1-0 Saymak, 2-0 Bel Hassani, 2-1 Damascan, 3-1 Thy; R: Ciss (For), Ghoochannejhad (PEC) |
| 14 | 23/11/2019 | Ajax | Heracles Almelo | 4-1 | 53.000 | Higler | 1-0 Promes, 2-0 Labyad, 3-0 Promes, 4-0 Huntelaar, 4-1 Dessers |
| 14 | 23/11/2019 | ADO Den Haag | Willem II | 3-3 | 10.889 | Lindhout | 0-1 Heerkens, 0-2 Pavlidis, 1-2 Necid, 1-3 Pavlidis, 2-3 Necid, 3-3 Goossens |
| 14 | 24/11/2019 | PSV | sc Heerenveen | 2-1 | 33.800 | Nijhuis | 1-0 en 2-0 Bergwijn, 2-1 Odgaard |
| 14 | 24/11/2019 | FC Groningen | Feyenoord | 1-1 | 21.096 | Manschot | 0-1 Sinisterra, 1-1 Memisevic (pen) |
| 14 | 24/11/2019 | VVV-Venlo | FC Twente | 2-1 | 6.730 | Vd Eijk | 1-0 Van Ooijen, 2-0 Soriano, 2-1 Vuckic |
| 14 | 24/11/2019 | RKC Waalwijk | FC Emmen | 1-1 | 6.645 | Martens | 0-1 De Leeuw, 1-1 Sow; R: Mulder (RKC) |
| 14 | 24/11/2019 | Sparta Rotterdam | Vitesse | 2-0 | 10.020 | Bax | 1-0 Mattheij, 2-0 Smeets |
| 15 | 29/11/2019 | sc Heerenveen | Vitesse | 3-2 | 17.883 | Makkelie | 0-1 Matavz, 0-2 Linssen, 1-2 Faik (pen), 2-2 Van Bergen, 3-2 Odgaard |
| 15 | 30/11/2019 | Willem II | Sparta Rotterdam | 4-0 | 14.250 | Mulder | 1-0 Nunnely, 2-0 Ndayishimiye, 3-0 Heerkens, 4-0 Köhlert |
| 15 | 30/11/2019 | FC Emmen | PSV | 1-1 | 8.309 | Higler | 0-1 Schwaab, 1-1 Kolar; R: Bijl (Emm) |
| 15 | 30/11/2019 | Fortuna Sittard | FC Groningen | 1-0 | 7.632 | Martens | 1-0 Karjalainen |
| 15 | 30/11/2019 | Heracles Almelo | ADO Den Haag | 4-0 | 10.150 | Manschot | 1-0 Dessers, 2-0 Mauro Junior, 3-0 Dessers, 4-0 Merkel |
| 15 | 01/12/2019 | Feyenoord | PEC Zwolle | 1-0 | 44.513 | Lindhout | 1-0 Berghuis |
| 15 | 01/12/2019 | AZ | VVV-Venlo | 1-0 | 6.007 | Vd Kerkhof | 1-0 Sugawara (Gespeeld in Den Haag) |
| 15 | 01/12/2019 | FC Twente | Ajax | 2-5 | 30.000 | Van Boekel | 1-0 Nakamura, 2-0 Aitor, 2-1 en 2-2 Lang, 2-3 Huntelaar, 2-4 Lang, 2-5 Huntelaar |
| 15 | 01/12/2019 | FC Utrecht | RKC Waalwijk | 0-1 | 18.103 | Vd Eijk | 0-1 Meulensten |
| 16 | 06/12/2019 | PEC Zwolle | AZ | 0-3 | 13.708 | Gözübüyük | 0-1 Boadu, 0-2 en 0-3 Idrissi |
| 16 | 06/12/2019 | Ajax | Willem II | 0-2 | 54.022 | Kuipers | 0-1 Ndayishimiye, 0-2 Dankerlui |
| 16 | 07/12/2019 | ADO Den Haag | FC Twente | 0-0 | 11.439 | Mulder | |
| 16 | 07/12/2019 | PSV | Fortuna Sittard | 5-0 | 33.300 | Lindhout | 1-0 Doan, 2-0 Malen, 3-0 Bergwijn (pen), 4-0 Ihattaren (pen), 5-0 Gakpo |
| 16 | 07/12/2019 | VVV-Venlo | FC Emmen | 2-0 | 6.580 | Bax | 1-0 Opoku, 2-0 Van Ooijen; R: Burnet (Emm) |
| 16 | 08/12/2019 | Vitesse | Feyenoord | 0-0 | 16.455 | Van Boekel | |
| 16 | 08/12/2019 | FC Groningen | FC Utrecht | 0-1 | 18.741 | Blom | 0-1 Ramselaar |
| 16 | 08/12/2019 | RKC Waalwijk | sc Heerenveen | 1-3 | 5.174 | Nagtegaal | 0-1 Kongolo, 1-1 Spierings, 1-2 Odgaard, 1-3 Dreyer |
| 16 | 08/12/2019 | Sparta Rotterdam | Heracles Almelo | 0-0 | 9.934 | Martens | R: Konings (Her) |
| 17 | 13/12/2019 | sc Heerenveen | Willem II | 1-2 | 18.121 | Higler | 0-1 Pavlidis, 1-1 Kongolo, 1-2 Ndayishimiye |
| 17 | 14/12/2019 | ADO Den Haag | FC Groningen | 1-1 | 11.049 | Kooij | 0-1 Gudmundsson, 1-1 Necid R: Zeefuik (Gro), Beugelsdijk (ADO) |
| 17 | 14/12/2019 | Fortuna Sittard | RKC Waalwijk | 3-2 | 8.391 | Kamphuis | 0-1 Mulder, 1-1 Diemers, 1-2 Leemans, 2-2 en 3-2 Damascan; R: Maatsen (RKC) |
| 17 | 14/12/2019 | VVV-Venlo | PEC Zwolle | 1-2 | 6.861 | Nagtegaal | 0-1 Paal, 0-2 Clement, 1-2 Bastiaans |
| 17 | 14/12/2019 | FC Twente | Vitesse | 0-3 | 26.500 | Lindhout | 0-1 Linssen, 0-2 Dicko, 0-3 Linssen |
| 17 | 15/12/2019 | AZ | Ajax | 1-0 | 17.002 | Makkelie | 1-0 Boadu |
| 17 | 15/12/2019 | FC Emmen | Sparta Rotterdam | 2-0 | 8.145 | Vd Graaf | 1-0 Peña, 2-0 De Leeuw |
| 17 | 15/12/2019 | Feyenoord | PSV | 3-1 | 47.625 | Nijhuis | 1-0, 2-0 (pen) en 3-0 (pen) Berghuis, 3-1 Pereiro |
| 17 | 15/12/2019 | Heracles Almelo | FC Utrecht | 1-3 | 10.200 | Gözübüyük | 1-0 Kiomourtzoglu, 1-1 Ramselaar, 1-2 Kerk, 1-3 Ramselaar |
| 18 | 20/12/2019 | RKC Waalwijk | FC Twente | 3-0 | 5.154 | Vd Kerkhof | 1-0 Tahiri, 2-0 en 3-0 Spierings R: Verdonk (Twe) |
| 18 | 21/12/2019 | sc Heerenveen | Heracles Almelo | 1-1 | 20.424 | Kamphuis | 0-1 Dessers, 1-1 Veerman |
| 18 | 21/12/2019 | PSV | PEC Zwolle | 4-1 | 33.000 | Manschot | 0-1 Saymak 1-1 Hendriks, 2-1 Ihattaren, 3-1 Bruma, 4-1 Gakpo |
| 18 | 21/12/2019 | Sparta Rotterdam | AZ | 3-0 | 10.031 | Blom | 1-0 Auassar, 2-0 Smeets, 3-0 Dervisoglu (pen) R: Bizot (AZ) |
| 18 | 21/12/2019 | Willem II | Fortuna Sittard | 0-0 | 13.587 | Nijhuis | |
| 18 | 22/12/2019 | Ajax | ADO Den Haag | 6-1 | 53.976 | Higler | 1-0 Ziyech, 2-0 Van de Beek, 3-0 Ekkelenkamp, 4-0 Gravenberch, 5-0 Tadic, 6-0 Traoré, 6-1 Goossens; R: Bakker (ADO) |
| 18 | 22/12/2019 | FC Groningen | FC Emmen | 2-0 | 20.136 | Makkelie | 1-0 en 2-0 Sierhuis; R: Heylen (Emm) |
| 18 | 22/12/2019 | FC Utrecht | Feyenoord | 1-2 | 21.103 | Kuipers | 0-1 Köckcü, 1-1 Hoogma, 1-2 Toornstra R: Hoogma (Utr) |
| 18 | 22/12/2019 | Vitesse | VVV-Venlo | 3-0 | 13.454 | Mulder | 1-0 Bazoer, 2-0 Matavz, 3-0 Linssen |
| 19 | 17/01/2020 | PEC Zwolle | FC Utrecht | 3-3 | 13.102 | Kamphuis | 0-1 Gustafson (pen), 1-1 Van Duinen, 2-1 Paal, 2-2 Kark, 2-3 Abass, 3-3 Nakayama |
| 19 | 18/01/2020 | Fortuna Sittard | Vitesse | 1-3 | 8.238 | Vd Eijk | 0-1 Tannane, 0-2 en 0-3 Matavz, 1-3 Ciss |
| 19 | 18/01/2020 | FC Twente | FC Groningen | 0-0 | 26.500 | Higler | |
| 19 | 18/01/2020 | Feyenoord | sc Heerenveen | 3-1 | 46.000 | Mulder | 1-0 Sinisterra, 2-0 en 3-0 Jørgensen, 3-1 Veerman |
| 19 | 18/01/2020 | AZ | Willem II | 1-3 | 15.442 | Kuipers | 1-0 Idrissi, 1-1 Köhlert, 1-2 Pavlidis, 1-3 Ndayishimiye |
| 19 | 19/01/2020 | VVV-Venlo | PSV | 1-1 | 7.059 | Makkelie | 1-0 Opoku (pen), 1-1 Dumfries |
| 19 | 19/01/2020 | Ajax | Sparta Rotterdam | 2-1 | 53.000 | Lindhout | 1-0 Van de Beek, 2-0 Gravenberch, 2-1 Piroe |
| 19 | 19/01/2020 | FC Emmen | Heracles Almelo | 1-0 | 8.176 | Kooij | 1-0 Kolar |
| 19 | 19/01/2020 | ADO Den Haag | RKC Waalwijk | 2-0 | 12.433 | Manschot | 1-0 Pinas, 2-0 Meijers; R: Delcroix (RKC) |
| 20 | 24/01/2020 | FC Utrecht | ADO Den Haag | 4-0 | 17.319 | Nijhuis | 1-0 Peterson, 2-0 Klaiber, 3-0 Kerk, 4-0 Klaiber |
| 20 | 25/01/2020 | sc Heerenveen | AZ | 1-2 | 19.638 | Blom | 0-1 De Wit, 1-1 Ejuke, 1-2 Boadu |
| 20 | 25/01/2020 | Heracles Almelo | Feyenoord | 2-3 | 10.686 | Makkelie | 1-0 Rossmann, 1-1 Toornstra, 1-2 Sinisterra, 1-3 Botteghin, 2-3 Rossmann |
| 20 | 25/01/2020 | RKC Waalwijk | VVV-Venlo | 1-2 | 6.103 | Vd Graaf | 1-0 Hansson, 1-1 Opoku, 1-2 Darfalu |
| 20 | 25/01/2020 | Sparta Rotterdam | Fortuna Sittard | 1-1 | 9.821 | Higler | 0-1 Damascan, 1-1 Mattheij |
| 20 | 26/01/2020 | Vitesse | FC Emmen | 1-1 | 13.265 | Nagtegaal | 1-0 Linssen, 1-1 De Leeuw |
| 20 | 26/01/2020 | FC Groningen | Ajax | 2-1 | 22.315 | Manschot | 1-0 Sierhuis, 2-0 Lundqvist, 2-1 Van de Beek |
| 20 | 26/01/2020 | Willem II | PEC Zwolle | 0-0 | 13.337 | Blank | R: Lam (PEC) |
| 20 | 26/01/2020 | PSV | FC Twente | 1-1 | 33.600 | Mulder | 1-0 Dumfries, 1-1 Vuckic; R: Afellay (PSV) |
| 21 | 31/01/2020 | AZ | RKC Waalwijk | 4-0 | 14.712 | Gözübüyük | 1-0 Idrissi, 2-0 Boadu, 3-0 Idrissi, 4-0 Stengs |
| 21 | 01/02/2020 | ADO Den Haag | Vitesse | 0-0 | 12.387 | Kooij | |
| 21 | 01/02/2020 | Feyenoord | FC Emmen | 3-0 | 47.084 | Vd Graaf | 1-0 Özyakup, 2-0 Jørgensen, 3-0 Sinisterra |
| 21 | 01/02/2020 | FC Twente | Sparta Rotterdam | 2-0 | 26.300 | Kamphuis | 1-0 Bijen, 2-0 Lang; R: Rayhi (Spa) |
| 21 | 01/02/2020 | PEC Zwolle | FC Groningen | 1-0 | 12.844 | Van Boekel | 1-0 Nakayama |
| 21 | 02/02/2020 | Willem II | Heracles Almelo | 1-0 | 13.417 | Blom | 1-0 Holmén |
| 21 | 02/02/2020 | Fortuna Sittard | sc Heerenveen | 2-1 | 8.371 | Oostrom | 0-1 Van Bergen, 1-1 Passlack, 2-1 Botman (e.d.) |
| 21 | 02/02/2020 | VVV-Venlo | FC Utrecht | 1-1 | 6.265 | Higler | 1-0 Darfalou (pen), 1-1 Gustafson (pen) |
| 21 | 02/02/2020 | Ajax | PSV | 1-0 | 53.055 | Kuipers | 1-0 Promes |
| 22 | 07/02/2020 | Heracles Almelo | Fortuna Sittard | 2-0 | 10.235 | Kuipers | 1-0 (pen) en 2-0 Dessers; R: Cox (For) |
| 22 | 08/02/2020 | FC Groningen | Vitesse | 1-0 | 17.884 | Vd Kerkhof | 1-0 Lundqvist (pen) |
| 22 | 08/02/2020 | sc Heerenveen | VVV-Venlo | 1-1 | 16.400 | Martens | 0-1 Opoku (pen), 1-1 Floranus |
| 22 | 08/02/2020 | PSV | Willem II | 3-0 | 34.700 | Lindhout | 1-0 Dumfries, 2-0 Thomas, 3-0 Ndayishimiye (e.d.) |
| 22 | 08/02/2020 | RKC Waalwijk | PEC Zwolle | 0-0 | 5.257 | Mulder | |
| 22 | 09/02/2020 | FC Utrecht | Ajax | 12:15 | |||
| 22 | 09/02/2020 | AZ | Feyenoord | 14:30 | |||
| 22 | 09/02/2020 | Sparta Rotterdam | ADO Den Haag | 4-2 | 8.083 | Makkelie | 0-1 Pinas, 1-1 Auassar, 2-1 Joosten, 3-1 Vrieds, 3-2 Summerville, 4-2 Harroui |
| 22 | 11/02/2020 | FC Emmen | FC Twente | 2-0 | 8.039 | Bax | 1-0 Frei, 2-0 Jansen |
| 23 | 14/02/2020 | VVV-Venlo | Heracles Almelo | 1-0 | 6.594 | Oostrom | 1-0 Post |
| 23 | 15/02/2020 | ADO Den Haag | PSV | 0-3 | 13.370 | Van Boekel | 0-1 Lamers (pen), 0-2 Thomas, 0-3 Gakpo |
| 23 | 15/02/2020 | FC Twente | AZ | 2-0 | 27.000 | Lindhout | 1-0 Aburjana, 2-0 Menig |
| 23 | 15/02/2020 | Fortuna Sittard | FC Emmen | 0-0 | 7.856 | Manschot | R: Ninaj (For) |
| 23 | 16/02/2020 | Vitesse | sc Heerenveen | 4-2 | 14.113 | Vd Graaf | 1-0 Linssen, 2-0 Matavz, 2-1 Kongolo, 2-2 Ejuke, 3-2 Linssen, 4-2 Tannane |
| 23 | 16/02/2020 | Ajax | RKC Waalwijk | 3-0 | 53.000 | Higler | 1-0 Tadic (pen), 2-0 Traoré, 3-0 Huntelaar |
| 23 | 16/02/2020 | Sparta Rotterdam | FC Groningen | 1-2 | 10.143 | Vd Eijk | 0-1 Asoro, 0-2 Lundqvist, 1-2 Rayhi (pen) |
| 23 | 16/02/2020 | Willem II | FC Utrecht | 1-1 | 14.107 | Mulder | 0-1 Bahebeck, 1-1 Gladon |
| 23 | 16/02/2020 | PEC Zwolle | Feyenoord | 3-4 | 13.822 | Gözübüyük | 1-0 Thy (pen), 2-0 Van Duinen, 2-1 Fer, 2-2 Berghuis, 3-2 Thy, 3-3 Berghuis, 3-4 Bozenik |
| 24 | 21/02/2020 | RKC Waalwijk | Sparta Rotterdam | 0-1 | 5.343 | Kooij | 0-1 Joosten |
| 24 | 22/02/2020 | FC Emmen | Willem II | 4-2 | 8.190 | Perez | 1-0 Araujo, 1-1 Llonch, 2-1 De Leeuw 3-1 Adzic, 3-2 Ndayishimiye (pen), 4-2 Pena |
| 24 | 23/02/2020 | AZ | PEC Zwolle | 2-0 | 15.306 | Kamphuis | 1-0 en 2-0 Koopmeiners (pen) |
| 24 | 22/02/2020 | Feyenoord | Fortuna Sittard | 2-1 | 46.016 | Nijhuis | 1-0 Berghuis (pen), 1-1 Diemers (pen), 2-1 Bozenik |
| 24 | 22/02/2020 | FC Groningen | VVV-Venlo | 0-1 | 16.734 | Kuipers | 0-1 Darfalou |
| 24 | 23/02/2020 | FC Utrecht | FC Twente | 2-1 | 18.491 | Manschot | 0-1 Vuckic, 1-1 Kerk, 2-1 Arweiler |
| 24 | 22/02/2020 | sc Heerenveen | ADO Den Haag | 2-2 | 16.640 | Vd Kerkhof | 0-1 Bogle, 0-2 Kongolo (e.d.), 1-2 Veerman, 2-2 Halilovic |
| 24 | 23/02/2020 | Vitesse | PSV | 1-2 | 15.509 | Makkelie | 1-0 Matavz, 1-1 Lammers (pen), 1-2 Gakpo |
| 24 | 23/02/2020 | Heracles Almelo | Ajax | 1-0 | 12.080 | Van Boekel | 1-0 Dessers |
| 25 | 28/02/2020 | Willem II | FC Groningen | 3-1 | 13.607 | Martens | 1-0 Nunnely, 2-0 Pavlidis, 3-0 Köhlert, 3-1 El Messaouidi |
| 25 | 29/02/2020 | ADO Den Haag | Heracles Almelo | 0-0 | 11.207 | Bax | R: Pinas (ADO) |
| 25 | 29/02/2020 | VVV-Venlo | Fortuna Sittard | 0-0 | 7.115 | Makkelie | |
| 25 | 29/02/2020 | PEC Zwolle | Vitesse | 4-3 | 13.088 | Lindhout | 1-0 Hamer, 1-1 Matavz, 1-2 Tannane, 2-2 Paal, 3-2 Ghoochannejhad (pen), 3-3 Tannane, 4-3 Clement |
| 25 | 29/02/2020 | FC Twente | sc Heerenveen | 2-3 | 27.000 | Kooij | 0-1 Faik, 0-2 Ejuke, 0-3 Veerman, 1-3 Vuckic (pen), 3-2 Selahi |
| 25 | 01/03/2020 | Ajax | AZ | 0-2 | 52.707 | Gözübüyük | 0-1 Boadu, 0-2 Idrissi |
| 25 | 01/03/2020 | PSV | Feyenoord | 1-1 | 35.000 | Higler | 0-1 Botthegin, 1-1 Gakpo |
| 25 | 01/03/2020 | Sparta Rotterdam | FC Emmen | 5-1 | 10.600 | Nijhuis | 1-0 Joosten, 2-0 Rayhi, 3-0 Vriends, 3-1 De Leeuw, 4-1 Araujo (e.d.), 5-1 Harroui |
| 25 | 01/03/2020 | RKC Waalwijk | FC Utrecht | 2-1 | 5.134 | Kamphuis | 0-1 Kerk, 1-1 Sow, 2-1 Maatsen |
| 26 | 06/03/2020 | Fortuna Sittard | PEC Zwolle | 1-1 | 10.071 | Vd Kerkhof | 1-0 Cox, 1-1 Thy (Pen) |
| 26 | 07/03/2020 | FC Emmen | VVV-Venlo | 3-0 | 8.100 | Mulder | 1-0 Laursen, 2-0 Kolar, 3-0 Laursen |
| 26 | 07/03/2020 | AZ | ADO Den Haag | 4-0 | 16.117 | Higler | 1-0 Koopmeiners (pen), 2-0 Wijndal, 3-0 Koopmeiners, 4-0 Druijf |
| 26 | 07/03/2020 | sc Heerenveen | Ajax | 1-3 | 25.950 | Manschot | 0-1 en 0-2 Tadic, 0-3 Promes, 1-3 Van Bergen |
| 26 | 07/03/2020 | Vitesse | FC Twente | 1-0 | 14.210 | Martens | 1-0 Grot |
| 26 | 08/03/2020 | FC Utrecht | Sparta Rotterdam | 5-1 | 20.624 | Lindhout | 1-0 Ramselaar, 2-0 Dalmau, 3-0 Gustafson, 4-0 Ramselaar, 5-0 Klaiber, 5-1 Piroe |
| 26 | 08/03/2020 | Feyenoord | Willem II | 2-0 | 47.500 | Van Boekel | 1-0 Toornstra, 2-0 Berghuis (pen) |
| 26 | 08/03/2020 | Heracles Almelo | RKC Waalwijk | 4-2 | 10.412 | Vd Graaf | 0-1 Leemans (pen), 0-2 Tahiri, 1-2 Van den Buijs, 2-2 en 3-2 Van de Water, 4-2 Burgzorg |
| 26 | 08/03/2020 | FC Groningen | PSV | 0-1 | 19.116 | Gözübüyük | 0-1 Dumfries |
| 27 | 13/03/2020 | ADO Den Haag | Fortuna Sittard | Niet gespeeld | |||
| 27 | 14/03/2020 | Willem II | sc Heerenveen | Niet gespeeld | |||
| 27 | 14/03/2020 | Ajax | FC Twente | Niet gespeeld | |||
| 27 | 14/03/2020 | FC Utrecht | Vitesse | Niet gespeeld | |||
| 27 | 14/03/2020 | PEC Zwolle | Heracles Almelo | Niet gespeeld | |||
| 27 | 15/03/2020 | Sparta Rotterdam | Feyenoord | Niet gespeeld | |||
| 27 | 15/03/2020 | PSV | FC Emmen | Niet gespeeld | |||
| 27 | 15/03/2020 | VVV-Venlo | AZ | Niet gespeeld | |||
| 27 | 15/03/2020 | RKC Waalwijk | FC Groningen | Niet gespeeld | |||
| 28 | 20/03/2020 | Heracles Almelo | Sparta Rotterdam | Niet gespeeld | |||
| 28 | 21/03/2020 | FC Twente | ADO Den Haag | Niet gespeeld | |||
| 28 | 21/03/2020 | Vitesse | Willem II | Niet gespeeld | |||
| 28 | 21/03/2020 | PEC Zwolle | VVV-Venlo | Niet gespeeld | |||
| 28 | 21/03/2020 | sc Heerenveen | RKC Waalwijk | Niet gespeeld | |||
| 28 | 22/03/2020 | Fortuna Sittard | PSV | Niet gespeeld | |||
| 28 | 22/03/2020 | Feyenoord | Ajax | Niet gespeeld | |||
| 28 | 22/03/2020 | FC Groningen | AZ | Niet gespeeld | |||
| 28 | 22/03/2020 | FC Emmen | FC Utrecht | Niet gespeeld | |||
| 29 | 04/04/2020 | Sparta Rotterdam | sc Heerenveen | Niet gespeeld | |||
| 29 | 04/04/2020 | VVV-Venlo | Willem II | Niet gespeeld | |||
| 29 | 04/04/2020 | PSV | Heracles Almelo | Niet gespeeld | |||
| 29 | 04/04/2020 | AZ | Vitesse | Niet gespeeld | |||
| 29 | 04/04/2020 | FC Utrecht | FC Groningen | Niet gespeeld | |||
| 29 | 05/04/2020 | RKC Waalwijk | Feyenoord | Niet gespeeld | |||
| 29 | 05/04/2020 | Ajax | PEC Zwolle | Niet gespeeld | |||
| 29 | 05/04/2020 | ADO Den Haag | FC Emmen | Niet gespeeld | |||
| 29 | 05/04/2020 | FC Twente | Fortuna Sittard | Niet gespeeld | |||
| 30 | 10/04/2020 | FC Groningen | sc Heerenveen | Niet gespeeld | |||
| 30 | 11/04/2020 | Vitesse | RKC Waalwijk | Niet gespeeld | |||
| 30 | 11/04/2020 | Feyenoord | VVV-Venlo | Niet gespeeld | |||
| 30 | 11/04/2020 | Heracles Almelo | AZ | Niet gespeeld | |||
| 30 | 11/04/2020 | Willem II | ADO Den Haag | Niet gespeeld | |||
| 30 | 12/04/2020 | Fortuna Sittard | FC Utrecht | Niet gespeeld | |||
| 30 | 12/04/2020 | FC Emmen | Ajax | Niet gespeeld | |||
| 30 | 12/04/2020 | PEC Zwolle | FC Twente | Niet gespeeld | |||
| 30 | 12/04/2020 | PSV | Sparta Rotterdam | Niet gespeeld | |||
| 31 | 21/04/2020 | AZ | PSV | Niet gespeeld | |||
| 31 | 21/04/2020 | Sparta Rotterdam | PEC Zwolle | Niet gespeeld | |||
| 31 | 22/04/2020 | ADO Den Haag | Feyenoord | Niet gespeeld | |||
| 31 | 22/04/2020 | RKC Waalwijk | Willem II | Niet gespeeld | |||
| 31 | 22/04/2020 | FC Groningen | Fortuna Sittard | Niet gespeeld | |||
| 31 | 22/04/2020 | sc Heerenveen | FC Emmen | Niet gespeeld | |||
| 31 | 22/04/2020 | FC Utrecht | Heracles Almelo | Niet gespeeld | |||
| 31 | 23/04/2020 | FC Twente | VVV-Venlo | Niet gespeeld | |||
| 31 | 23/04/2020 | Ajax | Vitesse | Niet gespeeld | |||
| 32 | 25/04/2020 | PSV | FC Utrecht | Niet gespeeld | |||
| 32 | 25/04/2020 | Fortuna Sittard | AZ | Niet gespeeld | |||
| 32 | 25/04/2020 | FC Emmen | RKC Waalwijk | Niet gespeeld | |||
| 32 | 25/04/2020 | Feyenoord | FC Groningen | Niet gespeeld | |||
| 32 | 25/04/2020 | PEC Zwolle | sc Heerenveen | Niet gespeeld | |||
| 32 | 26/04/2020 | Heracles Almelo | FC Twente | Niet gespeeld | |||
| 32 | 26/04/2020 | VVV-Venlo | ADO Den Haag | Niet gespeeld | |||
| 32 | 26/04/2020 | Willem II | Ajax | Niet gespeeld | |||
| 32 | 26/04/2020 | Vitesse | Sparta Rotterdam | Niet gespeeld | |||
| 33 | 03/05/2020 | Ajax | VVV-Venlo | Niet gespeeld | |||
| 33 | 03/05/2020 | AZ | FC Utrecht | Niet gespeeld | |||
| 33 | 03/05/2020 | FC Groningen | ADO Den Haag | Niet gespeeld | |||
| 33 | 03/05/2020 | sc Heerenveen | PSV | Niet gespeeld | |||
| 33 | 03/05/2020 | Sparta Rotterdam | Willem II | Niet gespeeld | |||
| 33 | 03/05/2020 | FC Twente | Feyenoord | Niet gespeeld | |||
| 33 | 03/05/2020 | Vitesse | Heracles Almelo | Niet gespeeld | |||
| 33 | 03/05/2020 | RKC Waalwijk | Fortuna Sittard | Niet gespeeld | |||
| 33 | 03/05/2020 | PEC Zwolle | FC Emmen | Niet gespeeld | |||
| 34 | 10/05/2020 | ADO Den Haag | PEC Zwolle | Niet gespeeld | |||
| 34 | 10/05/2020 | FC Emmen | AZ | Niet gespeeld | |||
| 34 | 10/05/2020 | Feyenoord | Vitesse | Niet gespeeld | |||
| 34 | 10/05/2020 | Heracles Almelo | FC Groningen | Niet gespeeld | |||
| 34 | 10/05/2020 | PSV | RKC Waalwijk | Niet gespeeld | |||
| 34 | 10/05/2020 | Fortuna Sittard | Ajax | Niet gespeeld | |||
| 34 | 10/05/2020 | FC Utrecht | sc Heerenveen | Niet gespeeld | |||
| 34 | 10/05/2020 | VVV-Venlo | Sparta Rotterdam | Niet gespeeld | |||
| 34 | 10/05/2020 | Willem II | FC Twente | Niet gespeeld |
Topscorers
| 1 | Steven Berghuis | Feyenoord | 15 |
| Cyriel Dessers | Heracles Almelo | 15 | |
| 3 | Myron Boadu | AZ | 14 |
| Bryan Linssen | Vitesse | 14 | |
| 5 | Oussama Idrissi | AZ | 13 |
| 6 | Quincy Promes | Ajax | 12 |
| Tim Matavz | Vitesse | 12 | |
| 8 | Donyell Malen | PSV | 11 |
| Teun Koopmeiners | AZ | 11 | |
| Vangelis Pavlidis | Willem II | 11 | |
| Dusan Tadic | Ajax | 11 | |
| Haris Vuckic | FC Twente | 11 |
Uitslagenmatrix
| ADO | AJA | AZ | EMM | EXC | FEY | FOR | GRA | GRO | HEE | HER | NAC | PEC | PSV | UTR | VIT | VVV | WIL | |
| ADO Den Haag | * | 1-5 | 0-1 | 1-2 | 3-1 | 2-2 | 3-1 | 0-0 | 1-0 | 2-3 | 2-0 | 1-1 | 1-0 | 0-7 | 5-0 | 3-3 | 2-4 | 6-2 |
| Ajax | 5-1 | * | 5-0 | 5-0 | 6-2 | 3-0 | 4-0 | 8-0 | 3-0 | 4-4 | 1-1 | 5-0 | 2-1 | 3-1 | 4-1 | 4-2 | 6-0 | 2-0 |
| AZ | 2-3 | 1-0 | * | 5-0 | 2-1 | 1-1 | 4-2 | 1-0 | 1-0 | 2-3 | 2-1 | 5-0 | 2-2 | 1-0 | 3-0 | 0-0 | 3-0 | 0-2 |
| FC Emmen | 3-2 | 2-5 | 1-4 | * | 1-2 | 1-4 | 3-3 | 1-1 | 1-0 | 2-0 | 1-1 | 2-0 | 0-1 | 2-2 | 2-0 | 0-3 | 1-1 | 0-2 |
| Excelsior | 2-4 | 1-7 | 4-2 | 2-1 | * | 2-1 | 1-1 | 2-0 | 2-4 | 3-3 | 0-3 | 1-2 | 0-2 | 0-2 | 3-3 | 2-0 | 1-0 | 1-1 |
| Feyenoord | 0-2 | 6-2 | 2-1 | 4-0 | 3-0 | * | 0-2 | 4-0 | 1-0 | 3-0 | 2-1 | 4-2 | 3-0 | 2-1 | 1-0 | 2-1 | 4-1 | 2-3 |
| Fortuna Sittard | 0-0 | 0-2 | 0-3 | 3-1 | 4-1 | 1-4 | * | 3-1 | 0-0 | 2-4 | 3-0 | 2-1 | 3-0 | 1-2 | 1-1 | 2-1 | 1-1 | 4-4 |
| De Graafschap | 1-1 | 1-4 | 1-1 | 1-0 | 4-1 | 2-0 | 5-1 | * | 0-1 | 0-5 | 1-2 | 3-0 | 0-2 | 1-4 | 0-1 | 2-2 | 1-2 | 2-1 |
| FC Groningen | 1-0 | 0-1 | 1-3 | 1-2 | 1-0 | 1-0 | 3-0 | 1-0 | * | 2-0 | 3-0 | 5-2 | 0-1 | 1-2 | 1-1 | 2-1 | 3-2 | 0-1 |
| sc Heerenveen | 1-1 | 0-4 | 0-2 | 1-1 | 1-0 | 3-5 | 3-1 | 0-3 | 1-1 | * | 3-5 | 2-1 | 1-1 | 2-2 | 2-3 | 1-1 | 2-2 | 4-2 |
| Heracles Almelo | 4-2 | 1-0 | 3-2 | 2-1 | 4-5 | 0-2 | 6-0 | 4-0 | 4-1 | 2-1 | * | 1-0 | 0-2 | 0-4 | 1-5 | 3-2 | 4-1 | 3-4 |
| NAC Breda | 1-1 | 0-3 | 0-3 | 1-1 | 0-2 | 0-4 | 2-3 | 3-0 | 0-0 | 4-2 | 2-1 | * | 0-0 | 0-2 | 0-4 | 2-1 | 1-1 | 2-2 |
| PEC Zwolle | 2-3 | 1-4 | 0-0 | 3-0 | 2-0 | 3-1 | 5-0 | 0-3 | 3-2 | 2-3 | 1-1 | 0-0 | * | 1-2 | 4-3 | 0-2 | 2-4 | 2-3 |
| PSV | 3-1 | 3-0 | 3-1 | 6-0 | 6-0 | 1-1 | 5-0 | 2-1 | 2-1 | 3-0 | 3-1 | 2-0 | 4-0 | * | 4-0 | 1-0 | 4-0 | 6-1 |
| FC Utrecht | 3-0 | 1-3 | 2-1 | 1-2 | 0-0 | 3-2 | 2-1 | 5-0 | 0-0 | 3-1 | 3-1 | 2-1 | 2-0 | 2-2 | * | 0-0 | 1-1 | 0-1 |
| Vitesse | 1-1 | 0-4 | 2-2 | 1-1 | 3-2 | 1-1 | 2-1 | 6-1 | 5-1 | 2-2 | 4-0 | 4-1 | 4-1 | 3-3 | 2-1 | * | 2-1 | 3-2 |
| VVV-Venlo | 2-0 | 0-1 | 2-2 | 2-3 | 1-0 | 0-3 | 3-2 | 4-1 | 0-0 | 1-1 | 0-1 | 3-0 | 3-0 | 0-1 | 2-6 | 1-3 | * | 2-1 |
| Willem II | 0-3 | 1-4 | 2-1 | 2-3 | 2-2 | 1-1 | 3-2 | 3-2 | 1-2 | 1-5 | 5-0 | 2-0 | 2-0 | 0-3 | 0-1 | 1-3 | 0-1 | * |
Eindstand
| 1 | Ajax * ** | 34 | 28 | 2 | 4 | 86 | 119 | 32 | + 87 | 51.082 |
| 2 | PSV ** | 34 | 26 | 5 | 3 | 83 | 98 | 26 | + 72 | 34.071 |
| 3 | Feyenoord *** | 34 | 20 | 5 | 9 | 65 | 75 | 41 | + 34 | 41.329 |
| 4 | AZ *** | 34 | 17 | 7 | 10 | 58 | 64 | 43 | + 21 | 15.139 |
| 5 | Vitesse + | 34 | 14 | 11 | 9 | 53 | 70 | 51 | + 19 | 15.238 |
| 6 | FC Utrecht + *** | 34 | 15 | 8 | 11 | 53 | 60 | 51 | + 9 | 18.841 |
| 7 | Heracles Almelo + | 34 | 15 | 3 | 16 | 48 | 61 | 68 | −7 | 10.992 |
| 8 | FC Groningen + | 34 | 13 | 6 | 15 | 45 | 39 | 41 | −2 | 17.690 |
| 9 | ADO Den Haag | 34 | 12 | 9 | 13 | 45 | 58 | 63 | −5 | 12.555 |
| 10 | Willem II | 34 | 13 | 5 | 16 | 44 | 58 | 72 | −14 | 12.998 |
| 11 | sc Heerenveen | 34 | 10 | 11 | 13 | 41 | 64 | 73 | −9 | 18.743 |
| 12 | VVV-Venlo | 34 | 11 | 8 | 15 | 41 | 47 | 63 | −16 | 6.828 |
| 13 | PEC Zwolle | 34 | 11 | 6 | 17 | 39 | 44 | 57 | −13 | 13.470 |
| 14 | FC Emmen | 34 | 10 | 8 | 16 | 38 | 41 | 72 | −31 | 8.249 |
| 15 | Fortuna Sittard | 34 | 9 | 7 | 18 | 34 | 50 | 80 | −30 | 8.610 |
| 16 | Excelsior ^^ | 34 | 9 | 6 | 19 | 33 | 46 | 79 | −33 | 4.214 |
| 17 | De Graafschap ^^ | 34 | 8 | 5 | 21 | 29 | 38 | 75 | −37 | 12.321 |
| 18 | NAC Breda ^ | 34 | 5 | 8 | 21 | 23 | 29 | 74 | −45 | 18.262 |
Wedstrijden
| R | Datum: | Thuis: | Uit: | Sc.: | Ts.: | Ar: | Details: |
|---|---|---|---|---|---|---|---|
| 1 | 10/08/2018 | PEC Zwolle | sc Heerenveen | 2-3 | 14.000 | Higler | 1-0 Van Duinen (pen), 1-1 en 1-2 Thorsby, 1-3 Zeneli, 2-3 Van Duinen (pen); R: Thorsby (Hee) |
| 1 | 11/08/2018 | Willem II | VVV-Venlo | 0-1 | 11.800 | Dieperink | 0-1 Post |
| 1 | 11/08/2018 | Ajax | Heracles Almelo | 1-1 | 45.000 | Gözübüyük | 0-1 Peterson, 1-1 De Ligt |
| 1 | 11/08/2018 | PSV | FC Utrecht | 4-0 | 33.100 | Nijhuis | 1-0 Pereiro, 2-0 Bergwijn, 3-0 Lozano, 4-0 Dumfries |
| 1 | 11/08/2018 | Excelsior | Fortuna Sittard | 2-1 | 4.250 | Mulder | 1-0 Matheij, 1-1 Smeets; R: Bruins (Exc) |
| 1 | 12/08/2018 | ADO Den Haag | FC Emmen | 1-2 | 11.324 | Martens | 0-1 Bijl, 0-2 Jansen, 1-2 Becker |
| 1 | 12/08/2018 | De Graafschap | Feyenoord | 2-0 | 12.600 | Van Boekel | 1-0 Serrarens, 2-0 Nijland; R: Botteghin, Boëtius (Fey) |
| 1 | 12/08/2018 | Vitesse | FC Groningen | 5-1 | 13.434 | Lindhout | 1-0 Linssen, 1-1 Doan, 2-1 Bero, 3-1 Beerens, 4-1 Clarke-Salter, 5-1 Matavz |
| 1 | 12/08/2018 | AZ | NAC Breda | 5-0 | 14.299 | Makkelie | 1-0 Svensson, 2-0 Hatzidiakos, 3-0 Boadu, 4-0 Koopmeiners, 5-0 Johnsen |
| 2 | 17/08/2018 | FC Groningen | Willem II | 0-1 | 16.500 | Manschot | 0-1 Crowley |
| 2 | 18/08/2018 | NAC Breda | De Graafschap | 3-0 | 18.710 | Gözübüyük | 1-0 Te Vrede, 2-0 Mets, 3-0 Nijholt |
| 2 | 18/08/2018 | VVV-Venlo | Ajax | 0-1 | 8.000 | Blom | 0-1 Tadic (pen) |
| 2 | 18/08/2018 | Fortuna Sittard | PSV | 1-2 | 11.135 | Van Boekel | 0-1 Lozano, 1-1 Novakovich, 1-2 Rigo |
| 2 | 18/08/2018 | Heracles Almelo | ADO Den Haag | 4-2 | 10.414 | Kooij | 1-0 Peterson (pen), 2-0 Van Hintum, 2-1 Malone, 2-2 Breukers (e.d.), 3-2 Dalmau, 4-2 Peterson |
| 2 | 19/08/2018 | FC Utrecht | PEC Zwolle | 2-0 | 18.036 | Vd Kerkhof | 1-0 Van Overeem, 2-0 Klaiber; R: Van Overeem (Utr) |
| 2 | 19/08/2018 | Feyenoord | Excelsior | 3-0 | 45.000 | Makkelie | 1-0 Van Persie, 2-0 St. Juste, 3-0 Van der Heijden |
| 2 | 19/08/2018 | FC Emmen | AZ | 1-4 | 8.085 | Lindhout | 0-1 Boadu, 1-1 Bakker, 1-2 Ouwejan, 1-3 en 1-4 Idrissi |
| 2 | 19/08/2018 | sc Heerenveen | Vitesse | 1-1 | 16.080 | Mulder | 1-0 Vlap, 1-1 Matavz |
| 3 | 24/08/2018 | ADO Den Haag | Fortuna Sittard | 3-1 | 11.600 | Higler | 1-0 Lorenzen, 2-0 en 3-0 (pen) El Khayati, 3-1 Semedo |
| 3 | 25/08/2018 | Ajax | FC Emmen | 5-0 | 47.500 | Nijhuis | 1-0 Ziyech, 2-0 en 3-0 Huntelaar, 4-0 Tadic, 5-0 Bijl (e.d.) |
| 3 | 25/08/2018 | De Graafschap | FC Groningen | 0-1 | 12.143 | Bax | 0-1 Breij |
| 3 | 25/08/2018 | NAC Breda | Excelsior | 0-2 | 18.227 | Manschot | 0-1 Massaoud, 0-2 Fortes |
| 3 | 25/08/2018 | PEC Zwolle | PSV | 1-2 | 13.255 | Kuipers | 0-1 De Jong, 1-1 Van Crooy, 1-2 De Jong |
| 3 | 26/08/2018 | Willem II | Heracles Almelo | 5-0 | 11.677 | Perez | 1-0 en 2-0 Avidjaj, 3-0, 4-0 (pen) en 5-0 Sol |
| 3 | 26/08/2018 | sc Heerenveen | Feyenoord | 3-5 | 21.700 | Kamphuis | 0-1 Toornstra, 0-2 Van Persie, 0-3 Toornstra, 0-4 Malacia, 1-3 Thorsby, 2-4 Pirie, 3-4 Bulthuis, 3-5 Ayoub |
| 3 | 26/08/2018 | FC Utrecht | VVV-Venlo | 1-1 | 15.226 | Makkelie | 1-0 Gavory, 1-1 Susic (pen) |
| 3 | 26/08/2018 | AZ | Vitesse | 0-0 | 14.702 | Gözübüyük | |
| 4 | 31/08/2018 | FC Emmen | De Graafschap | 1-1 | 8.218 | Vd Kerkhof | 1-0 Bannink, 1-1 Serrarens |
| 4 | 01/09/2018 | VVV-Venlo | sc Heerenveen | 1-1 | 6.235 | Lindhout | 0-1 Lammers, 1-1 Joosten |
| 4 | 01/09/2018 | PSV | Willem II | 6-1 | 33.300 | Kamphuis | 1-0 Hendrix, 2-0 Bergwijn, 3-0 Pereiro (pen), 4-0 Viergever, 4-1 Sol, 5-1 Viergever, 6-1 Bergwijn |
| 4 | 01/09/2018 | Excelsior | ADO Den Haag | 2-4 | 3.940 | Blom | 0-1 (en), 0-2, 0-3 en 0-4 El Khayati, 1-4 Anderson, 2-4 Mahmudov |
| 4 | 01/09/2018 | Fortuna Sittard | FC Utrecht | 1-1 | 7.643 | Dieperink | 0-1 Emanuelson, 1-1 Novakovich |
| 4 | 02/09/2018 | FC Groningen | PEC Zwolle | 0-1 | 10.054 | Kooij | 0-1 Van Crooy |
| 4 | 02/09/2018 | Heracles Almelo | AZ | 3-2 | 10.462 | Manschot | 0-1 Boadu, 1-1 Osman, 2-1 Peterson, 3-1 Duarte, 3-2 Johnsen |
| 4 | 02/09/2018 | Vitesse | Ajax | 0-4 | 19.231 | Van Boekel | 0-1 Ziyech, 0-2 Huntelaar, 0-3 Tadic, 0-4 Huntelaar |
| 4 | 02/09/2018 | Feyenoord | NAC Breda | 4-2 | 45.000 | Nijhuis | 1-0 Van Persie, 1-1 Nijholt (pen), 2-1 Van Leer (e.d.), 3-1 Van Persie, 4-1 Vilhena, 4-2 Te Vrede |
| 5 | 15/09/2018 | De Graafschap | VVV-Venlo | 1-2 | 11.702 | Martens | 0-1 Susic, 0-2 Post, 1-2 Burgzorg |
| 5 | 15/09/2018 | ADO Den Haag | PSV | 0-7 | 14.519 | Nijhuis | 0-1 Lozano, 0-2 De Jong, 0-3 Pereiro (p), 0-4 Lozano, 0-5 Guttierez, 0-6 Bergwijn, 0-7 Pereiro (pen) |
| 5 | 15/09/2018 | Willem II | Excelsior | 2-2 | 11.894 | Makkelie | 0-1 Bruins, 0-2 Mahmudov, 1-2 Sol, 2-2 Kristinsson |
| 5 | 15/09/2018 | Ajax | FC Groningen | 3-0 | 50.000 | Higler | 1-0 (pen) en 2-0 Huntelaar, 3-0 Tadic |
| 5 | 16/09/2018 | AZ | Feyenoord | 1-1 | 14.362 | Kuipers | 1-0 Gudmundsson, 1-1 Berghuis |
| 5 | 16/09/2018 | sc Heerenveen | Heracles Almelo | 3-5 | 15.500 | Van Boekel | 0-1 Dalmau, 1-1 Lammers, 1-2 Duarte, 2-2 Lammers (pen), 2-3 Peterson, 3-3 Thorsby, 3-4 Peterson, 3-5 Osman |
| 5 | 16/09/2018 | FC Utrecht | FC Emmen | 1-2 | 16.720 | Blom | 1-0 Van de Streek, 1-1 Slagveer, 1-2 Bijl R: Emanuelson (Utr) |
| 5 | 16/09/2018 | NAC Breda | Fortuna Sittard | 2-3 | 18.712 | Gözübüyük | 1-0 te Vrede, 1-1 en 1-2 El Moussaidi, 2-2 Kastaneer, 2-3 Ninaj |
| 5 | 16/09/2018 | PEC Zwolle | Vitesse | 0-2 | 13.325 | Bax | 0-1 en 0-2 Matavz |
| 6 | 21/09/2018 | Heracles Almelo | De Graafschap | 4-0 | 10.829 | Blank | 1-0 Vet (e.d.), 2-0 Petsron, 3-0 Kuwas, 4-0 Vermeij R: Serrarens (Gra) |
| 6 | 22/09/2018 | Fortuna Sittard | Willem II | 4-4 | 8.537 | Lindhout | 1-0 Dammers, 1-1 El Massaoudi (e.d.), 1-2 Sol, 2-2 Novakovich, 2-3 Avidjaj, 3-3 Novakovich, 3-4 Crowley, 4-4 Rodriguez |
| 6 | 22/09/2018 | Excelsior | sc Heerenveen | 3-3 | 4.008 | Vd Graaf | 1-0 Massaoud, 2-0 Bruins, 2-1 Bulthuis, 3-1 Messaoud, 3-2 Thorsby, 3-3 Hornkamp |
| 6 | 22/09/2018 | VVV-Venlo | NAC Breda | 3-0 | 6.167 | Kamphuis | 1-0 Opoku, 2-0 Susic (pen), 3-0 Grot R: Verschueren (NAC) |
| 6 | 22/09/2018 | FC Emmen | PEC Zwolle | 0-1 | 8.301 | Kuipers | 0-1 Dekker |
| 6 | 22/09/2018 | Vitesse | ADO Den Haag | 1-1 | 14.023 | Manschot | 1-0 Matavz, 1-1 El Khayati; R: Van der Werff (Vit) |
| 6 | 23/09/2018 | Feyenoord | FC Utrecht | 1-0 | 45.000 | Higler | 1-0 Van Persie |
| 6 | 23/09/2018 | FC Groningen | AZ | 1-3 | 15.901 | Van Boekel | 1-0 Chabot, 1-1 Idrissi, 1-2 Midtsjø, 1-3 Maher R: Zeefuik, Hrustic (Gro) |
| 6 | 23/09/2018 | PSV | Ajax | 3-0 | 35.000 | Makkelie | 1-0 Pereiro, 2-0 De Jong 3-0 Lozano |
| 7 | 29/09/2018 | sc Heerenveen | ADO Den Haag | 1-1 | 16.550 | S. Mulder | 1-0 Vlap, 1-1 Necid |
| 7 | 29/09/2018 | NAC Breda | PSV | 0-2 | 18.926 | Higler | 0-1 De Jong, 0-2 Malen |
| 7 | 29/09/2018 | Fortuna Sittard | Ajax | 0-2 | 12.004 | Van Boekel | 0-1 Dolberg, 0-2 Ziyech |
| 7 | 29/09/2018 | Excelsior | VVV-Venlo | 1-0 | 4.106 | Perez | 1-0 Omarsson; R: Massaoud (Exc) |
| 7 | 30/09/2018 | Heracles Almelo | FC Emmen | 2-1 | 10.217 | Makkelie | 1-0 Kuwas, 2-0 Peterson, 2-1 Jansen (pen) |
| 7 | 30/09/2018 | De Graafschap | Willem II | 2-1 | 12.005 | Bax | 1-0 Nijland, 1-1 Saddiki, 2-1 Lewis (e.d.) R: Akkaynak, Palacios (Wil) |
| 7 | 30/09/2018 | AZ | PEC Zwolle | 2-2 | 15.354 | Kamphuis | 1-0 Idrissi, 1-1 Van Crooy, 2-1 Til, 2-2 Flemming |
| 7 | 30/09/2018 | FC Groningen | FC Utrecht | 1-1 | 16.293 | Nijhuis | 0-1 Van de Streek, 1-1 Mendes Moreira R: Gustafson (Utr) |
| 7 | 30/09/2018 | Feyenoord | Vitesse | 2-1 | 45.000 | Gözübüyük | 0-1 Bero, 1-1 Botteghin, 2-1 Van Persie; R: Bruns, Doekhi (Vit), Van Persie (Fey) |
| 8 | 05/10/2018 | FC Utrecht | NAC Breda | 2-1 | 17.386 | Kuipers | 1-0 (pen) en 2-0 Gustafson, 2-1 Rosheuvel |
| 8 | 06/10/2018 | ADO Den Haag | FC Groningen | 1-0 | 11.485 | Lindhout | 1-0 Hooi |
| 8 | 06/10/2018 | PEC Zwolle | Excelsior | 2-0 | 13.562 | Vd Kerkhof | 1-0 Van Duinen, 2-0 Lam |
| 8 | 06/10/2018 | PSV | VVV-Venlo | 4-0 | 33.800 | S. Mulder | 1-0 Lozano, 2-0 De Jong, 3-0 Gutierrez, 4-0 Lozano (pen) |
| 8 | 06/10/2018 | De Graafschap | sc Heerenveen | 0-5 | 12.102 | Makkelie | 0-1 en 0-2 Lammers, 0-3 en 0-4 Vlap, 0-5 Hornkamp R: Bakker (gra) |
| 8 | 07/10/2018 | FC Emmen | Fortuna Sittard | 3-3 | 8.300 | Kooij | 1-0 Dammers (e.d.), 2-0 Arias, 2-1 Semedo, 3-1 Bannink, 3-2 Stokkers, 3-3 Rodriguez |
| 8 | 07/10/2018 | Willem II | Feyenoord | 1-1 | 13.550 | Blom | 0-1 Berghuis (pen), 1-1 Sol |
| 8 | 07/10/2018 | Vitesse | Heracles Almelo | 4-0 | 14.338 | Kamphuis | 1-0 Foor, 2-0 en 3-0 Darfalou, 4-0 Büttner (pen) |
| 8 | 07/10/2018 | Ajax | AZ | 5-0 | 50.000 | Higler | 1-0 Van de Beek, 2-0 Dolberg, 3-0 Van Rhijn (e.d.), 4-0 Ziyech, 5-0 Tadic |
| 9 | 20/10/2018 | PSV | FC Emmen | 6-0 | 34.200 | Nijhuis | 1-0 Pereiro, 2-0 en 3-0 De Jong, 4-0 Pereiro, 5-0 Gutierrez, 6-0 Lozano |
| 9 | 20/10/2018 | Excelsior | Vitesse | 2-0 | 4.397 | Kuipers | 1-0 Clark (e.d.), 2-0 Matheij; R: Stevens (Exc) |
| 9 | 20/10/2018 | sc Heerenveen | Ajax | 0-4 | 23.315 | Van Boekel | 0-1 Schöne, 0-2 Ziyech, 0-3 Tadic (pen), 0-4 Dolberg |
| 9 | 20/10/2018 | FC Utrecht | AZ | 2-1 | 18.294 | Blom | 0-1 Johnsen, 1-1 Emanuelson, 2-1 Van Rhijn (e.d.) |
| 9 | 21/10/2018 | NAC Breda | Willem II | 2-2 | 18.892 | Gözübüyük | 1-0 Te Vrede, 1-1 Meissner, 1-2 Avdijaj, 2-2 Rosheuvel |
| 9 | 21/10/2018 | Heracles Almelo | FC Groningen | 4-1 | 11.237 | Vd Kerkhof | 0-1 Mahi, 1-1 en 2-1 Dalmau, 3-1 en 4-1 Kuwas |
| 9 | 21/10/2018 | Feyenoord | PEC Zwolle | 3-0 | 45.600 | S. Mulder | 1-0 Clasie, 2-0 Jørgensen, 3-0 Berghuis |
| 9 | 21/10/2018 | VVV-Venlo | ADO Den Haag | 2-0 | 7.051 | Blank | 1-0 Mlapa (pen), 2-0 Grot |
| 9 | 21/10/2018 | Fortuna Sittard | De Graafschap | 3-1 | 8.527 | Martens | 1-0 Lamprou, 1-1 El Jebli, 2-1 Lamprou, 3-1 Ninaj |
| 10 | 26/10/2018 | FC Emmen | VVV-Venlo | 1-1 | 8.150 | Dieperink | 0-1 Mlapa, 1-1 Gronsveld; R: Janssen (VVV) |
| 10 | 27/10/2018 | ADO Den Haag | NAC Breda | 1-1 | 12.199 | Van Boekel | 0-1 Ilic, 1-1 El Khayati |
| 10 | 27/10/2018 | De Graafschap | Excelsior | 4-1 | 12.108 | Kooij | 1-0 Van Mieghem, 1-1 Omarsson, 2-1 Narsingh, 3-1 El Jebli, 4-1 Serrarens; R: Mattheij (Exc) |
| 10 | 27/10/2018 | FC Groningen | PSV | 1-2 | 18.445 | Makkelie | 1-0 Memisevic (pen), 1-1 Malen, 1-2 Dumfries |
| 10 | 27/10/2018 | PEC Zwolle | Heracles Almelo | 1-1 | 13.523 | Van de Graaf | 0-1 Dalmau, 1-1 Van Duinen |
| 10 | 28/10/2018 | Vitesse | Fortuna Sittard | 2-1 | 15.879 | Higler | 1-0 Van der Werff, 1-1 Vidigal, 2-1 Bero |
| 10 | 28/10/2018 | Willem II | FC Utrecht | 0-1 | 12.742 | Kamphuis | 0-1 Janssen |
| 10 | 28/10/2018 | Ajax | Feyenoord | 3-0 | 53.720 | Kuipers | 1-0 Bijlow (e.d.), 2-0 Ziyech, 3-0 Tadic R: St. Juste (Fey) |
| 10 | 28/10/2018 | AZ | sc Heerenveen | 2-3 | 16.535 | Gözübüyük | 1-0 Ouwejan, 1-1 en 1-2 Vlap, 2-2 Gudmundsson, 2-3 Lammers |
| 11 | 02/11/2018 | Excelsior | FC Groningen | 2-4 | 4.257 | Higler | 0-1 Mahi, 0-2 Doan, 1-2 Koolwijk, 1-3 Cassierra, 2-3 Bruins (pen), 2-4 Pohl |
| 11 | 03/11/2018 | NAC Breda | Heracles Almelo | 2-1 | 18.385 | Makkelie | 1-0 Ilic, 1-1 Kuwas, 2-1 Te Vrede |
| 11 | 03/11/2018 | Ajax | Willem II | 2-0 | 53.000 | Lindhout | 1-0 Dolberg, 2-0 De Jong |
| 11 | 03/11/2018 | AZ | De Graafschap | 1-0 | 15.428 | Kuipers | 1-0 Seuntjens |
| 11 | 03/11/2018 | PSV | Vitesse | 1-0 | 34.100 | Gözübüyük | 1-0 De Jong; R: Doekhi |
| 11 | 04/11/2018 | sc Heerenveen | FC Emmen | 1-1 | 19.835 | Blom | 1-0 Zeneli 1-1 Niemeijer |
| 11 | 04/11/2018 | FC Utrecht | ADO Den Haag | 3-0 | 15.946 | Manschot | 1-0 Dessers, 2-0 Janssen, 3-0 Van Overeem |
| 11 | 04/11/2018 | Fortuna Sittard | PEC Zwolle | 3-0 | 8.332 | Bax | 1-0 Stokkers, 2-0 en 3-0 Diemers (pen) |
| 12 | 09/11/2018 | PEC Zwolle | Willem II | 2-3 | 13.222 | Martens | 0-1 Dankerlui, 0-2 Sol, 1-2 Van Crooy, 1-3 Sol, 2-3 Flemming |
| 12 | 10/11/2018 | FC Emmen | NAC Breda | 2-0 | 8.300 | Kamphuis | 1-0 Cavlan, 2-0 Arias |
| 12 | 10/11/2018 | De Graafschap | PSV | 1-4 | 12.313 | Blom | 0-1 De Jong, 1-1 El Jebli, 1-2 Bergwijn, 1-3 Malen, 1-4 De Jong |
| 12 | 10/11/2018 | Vitesse | FC Utrecht | 2-1 | 15.131 | Makkelie | 1-0 Linssen, 2-0 Ødegaard, 2-1 Dessers |
| 12 | 10/11/2018 | VVV-Venlo | Fortuna Sittard | 3-2 | 7.534 | S. Mulder | 0-1 Stokkers, 1-1 Seuntjens, 2-1 en 3-1 Mlapa, 3-2 Vidigal |
| 12 | 11/11/2018 | FC Groningen | sc Heerenveen | 2-0 | 20.731 | Manschot | 1-0 Warmerdam, 2-0 Doan |
| 12 | 11/11/2018 | Excelsior | Ajax | 1-7 | 4.400 | Gözübüyük | 0-1 Van de Beek, 0-2 Schöne, 0-3 Van de Beek, 1-3 Messaoud, 1-4 Dolberg, 1-5 Schouten (e.d.), 1-6 Ziyech, 1-7 Neres |
| 12 | 11/11/2018 | ADO Den Haag | AZ | 0-1 | 12.717 | Higler | 0-1 Til |
| 12 | 11/11/2018 | Heracles Almelo | Feyenoord | 0-2 | 11.754 | Lindhout | 0-1 Blaswich (e.d.), 0-2 Toornstra |
| 13 | 24/11/2018 | PEC Zwolle | ADO Den Haag | 2-3 | 12.152 | S. Mulder | 1-0 Lam, 1-1 El Khayati (pen), 2-1 Leemans, 2-2 El Khayati, 2-3 Kuipers |
| 13 | 24/11/2018 | PSV | sc Heerenveen | 3-0 | 34.100 | Van Boekel | 1-0 Lozano, 2-0 De Jong, 3-0 Lozano R: Thorsby (Hee) |
| 13 | 24/11/2018 | NAC Breda | Ajax | 0-3 | 18.969 | Higler | 0-1 Mashart (e.d.), 0-2 Labyad, 0-3 Huntelaar |
| 13 | 24/11/2018 | Fortuna Sittard | Heracles Almelo | 3-0 | 7.545 | Gözübüyük | 1-0 Diemers (pen), 2-0 Stokkers, 3-0 El Massaoudi |
| 13 | 25/11/2018 | FC Emmen | Excelsior | 1-2 | 8.021 | Blank | 1-0 Jansen, 1-1 Massaoud, 1-2 Koolwijk |
| 13 | 25/11/2018 | FC Utrecht | De Graafschap | 5-0 | 18.802 | Lindhout | 1-0 Van de Streek, 2-0 Janssen, 3-0 Kerk, 4-0 en 5-0 Venema |
| 13 | 25/11/2018 | Feyenoord | FC Groningen | 1-0 | 45.000 | Blom | 1-0 Toornstra |
| 13 | 25/11/2018 | Willem II | Vitesse | 1-3 | 11.879 | Kuipers | 0-1 Bero, 0-2 Darfalu, 0-3 Linssen, 1-3 Sol (pen) |
| 13 | 25/11/2018 | VVV-Venlo | AZ | 2-2 | 6.217 | Manschot | 0-1 Koopmeiners, 0-2 Idrissi, 1-2 Mlapa, 2-2 Joosten; R: Van Ooijen (VVV) |
| 14 | 30/11/2018 | Excelsior | FC Utrecht | 3-3 | 4.400 | Martens | 1-0 Omarsson, 2-0 Koolwijk, 3-0 Bruins (pen), 3-1 Kerk, 3-2 Venema, 3-3 Gustafson (pen) R: Klaiber (Utr) |
| 14 | 01/12/2018 | Vitesse | FC Emmen | 1-1 | 15.000 | S. Mulder | 1-0 Linssen, 1-1 Cavlan |
| 14 | 01/12/2018 | AZ | Willem II | 0-2 | 15.787 | Lindhout | 0-1 en 0-2 Sol |
| 14 | 01/12/2018 | De Graafschap | PEC Zwolle | 0-2 | 12.008 | Vd Kerkhof | 0-1 Leemans, 0-2 Namli; R: Nieuwpoort (Gra) |
| 14 | 01/12/2018 | sc Heerenveen | Fortuna Sittard | 3-1 | 15.626 | Kooij | 1-0 Høegh, 2-0 Zeneli (pen), 2-1 Lamprou, 3-1 Van Amersfoort |
| 14 | 02/12/2018 | Ajax | ADO Den Haag | 5-1 | 53.000 | Van Boekel | 1-0 Neres, 2-0 Tagliafico, 2-1 Meijers, 3-1 De Ligt, 4-1 Van de Beek, 5-1 Dolberg |
| 14 | 02/12/2018 | Feyenoord | PSV | 2-1 | 45.000 | Gözübüyük | 1-0 Jørgensen, 2-0 Larsson, 2-1 Bergwijn |
| 14 | 02/12/2018 | Heracles Almelo | VVV-Venlo | 4-1 | 10.233 | Kamphuis | 1-0 Dalmau, 2-0 Duarte, 3-0 Peterson (pen), 3-1 Röseler, 4-1 Duarte |
| 14 | 02/12/2018 | FC Groningen | NAC Breda | 5-2 | 18.377 | Makkelie | 1-0 Mahi, 1-1 Rosheuvel, 1-2 Te Vrede, 2-2 Doan, 3-2 Zeefuik, 4-2 Mahi, 5-2 Memisevic |
| 11 | 06/12/2018 | Feyenoord | VVV-Venlo | 4-1 | 40.000 | Higler | 1-0 Vilhena, 2-0 Van Persie, 3-0 Larsson, 3-1 Susic, 4-1 Larsson |
| 15 | 07/12/2018 | Fortuna Sittard | AZ | 0-3 | 7.133 | Van de Graaf | 0-1 Seuntjens, 0-2 Idrissi, 0-3 Til |
| 15 | 07/12/2018 | PSV | Excelsior | 6-0 | 33.100 | Manschot | 1-0 De Jong, 2-0 Vd Meer (e.d.), 3-0 Mattheij (e.d.), 4-0 Malen, 5-0 Bergwijn, 6-0 De Jong |
| 15 | 08/12/2018 | Willem II | sc Heerenveen | 1-5 | 12.595 | S. Mulder | 0-1 Mihajlovic, 1-1 Akkaynak, 1-2 Rienstra (pen), 1-3 Vlap, 1-4 en 1-5 Van Bergen; R: Heerkens (Wil) |
| 15 | 08/12/2018 | PEC Zwolle | Ajax | 1-4 | 14.000 | Kamphuis | 0-1 Huntelaar, 0-2 De Jong, 1-2 Schöne (e.d.), 1-3 Schöne, 1-4 Tadic |
| 15 | 08/12/2018 | ADO Den Haag | De Graafschap | 0-0 | 11.105 | Bax | |
| 15 | 09/12/2018 | FC Utrecht | Heracles Almelo | 3-1 | 21.812 | Blom | 1-0 Gustafson (pen), 2-0 Kerk, 3-0 Emanuelson, 1-3 Rossmann |
| 15 | 09/12/2018 | VVV-Venlo | FC Groningen | 0-0 | 6.668 | Gözübüyük | |
| 15 | 09/12/2018 | FC Emmen | Feyenoord | 1-4 | 8.301 | Van Boekel | 0-1 Van der Heijden, 0-2 Berghuis, 1-2 Jansen, 1-3 Kökcü, 1-4 Vilhena |
| 15 | 09/12/2018 | NAC Breda | Vitesse | 2-1 | 18.280 | Lindhout | 1-0 Te Vrede, 1-1 Linssen, 2-1 Verschueren R: Bero (Vit) |
| 16 | 14/12/2018 | Willem II | ADO Den Haag | 0-3 | 12.163 | Kamphuis | 0-1 Falkenburg, 0-2 en 0-3 Immers |
| 16 | 15/12/2018 | PEC Zwolle | NAC Breda | 0-0 | 13.242 | Van Boekel | |
| 16 | 15/12/2018 | AZ | Excelsior | 2-1 | 14.427 | Vd Kerkhof | 0-1 Mahmudov, 1-1 Til, 2-1 Johnsen |
| 16 | 15/12/2018 | Heracles Almelo | PSV | 0-4 | 12.080 | Higler | 0-1 Bergwijn, 0-2 Schwaab, 0-3 Dumfries, 0-4 Pereiro; R: Drost, Czyborra (Her) |
| 16 | 15/12/2018 | Vitesse | VVV-Venlo | 2-1 | 13.249 | Bax | 1-0 Ødegaard, 1-1 Mlapa, 2-1 Darfalou |
| 16 | 16/12/2018 | sc Heerenveen | FC Utrecht | 2-3 | 17.575 | Van de Graaf | 0-1 Bergström, 0-2 Kark, 0-3 Tannane, 1-3 Vlap, 2-3 Van Amersfoort |
| 16 | 16/12/2018 | Ajax | De Graafschap | 8-0 | 52.000 | Blom | 1-0 Tadic, 2-0 Mazraoui, 3-0 en 4-0 Ziyech, 5-0 Blind, 6-0 Ziyech, 7-0 en 8-0 Blind |
| 16 | 16/12/2018 | FC Groningen | FC Emmen | 1-2 | 20.000 | Kuipers | 1-0 Mahi, 1-1 en 1-2 Pedersen |
| 16 | 16/12/2018 | Feyenoord | Fortuna Sittard | 0-2 | 42.500 | Manschot | 0-1 Hutten, 0-2 El Massaouidi |
| 17 | 21/12/2018 | VVV-Venlo | PEC Zwolle | 2-0 | 7.235 | Kooij | 1-0 Susic (pen), 2-0 Joosten; R: Boer (PEC) |
| 17 | 22/12/2018 | Fortuna Sittard | FC Groningen | 0-0 | 8.283 | Lindhout | R: Smeets (For) |
| 17 | 22/12/2018 | NAC Breda | sc Heerenveen | 4-2 | 18.352 | Kamphuis | 1-0 Te Vrede, 1-1 Rienstra, 1-2 Van Bergen, 2-2 Te Vrede, 3-2 en 4-2 Rosheuvel R: Rienstra, Kobayashi (Hee) |
| 17 | 22/12/2018 | PSV | AZ | 3-1 | 34.300 | Van Boekel | 0-1 Seuntjens, 1-1 Bergwijn, 2-1 Sadilek, 3-1 Lozano (pen) |
| 17 | 22/12/2018 | Excelsior | Heracles Almelo | 0-3 | 4.032 | Bax | 0-1 Peterson, 0-2 Kuwas, 0-3 Osman |
| 17 | 23/12/2018 | FC Utrecht | Ajax | 1-3 | 23.226 | Higler | 0-1 Dolberg, 0-2 Tadic (pen), 1-2 Venema, 1-3 De Jong |
| 17 | 23/12/2018 | De Graafschap | Vitesse | 2-2 | 12.600 | Kuipers | 1-0 Olijve, 1-1 Ødegaard, 2-1 Narsingh, 2-2 Bero |
| 17 | 23/12/2018 | ADO Den Haag | Feyenoord | 2-2 | 13.851 | Blom | 1-0 El Khayati, 1-1 Berghuis, 1-2 Larsson, 2-2 El Khayati (pen); R: Nieuwkoop (Fey) |
| 17 | 23/12/2018 | FC Emmen | Willem II | 0-2 | 8.301 | Gözübüyük | 0-1 Özbiliz, 0-2 Sol |
| 18 | 18/01/2019 | Vitesse | Excelsior | 3-2 | 12.231 | Vd Graaf | 1-0 Foor, 2-0 Linssen, 2-1 Edwards, 3-1 Van der Werff, 3-2 Schouten |
| 18 | 19/01/2019 | AZ | FC Utrecht | 3-0 | 16.104 | Lindhout | 1-0 Van Rhijn, 2-0 Seuntjens, 3-0 Stengs |
| 18 | 19/01/2019 | PEC Zwolle | Feyenoord | 3-1 | 13.724 | Van Boekel | 1-0 Van Polen, 1-1 Van Persie, 2-1 Van Crooy, 3-1 Namli |
| 18 | 19/01/2019 | ADO Den Haag | VVV-Venlo | 2-4 | 10.182 | Manschot | 1-0 Becker, 1-1 en 1-2 Joosten, 2-2 Falkenburg, 2-3 Mlapa (pen), 2-4 Grot; R: Zwinkels (ADO) |
| 18 | 19/01/2019 | FC Groningen | Heracles Almelo | 3-0 | 16.143 | Blom | 1-0 Memisevic (pen), 2-0 en 3-0 Bruns |
| 18 | 20/01/2019 | Willem II | NAC Breda | 2-0 | 14.400 | Kuipers | 1-0 Llonch, 2-0 Vrousai; R; El Allouchi (NAC) |
| 18 | 20/01/2019 | De Graafschap | Fortuna Sittard | 5-1 | 12.304 | S. Mulder | 1-0 en 2-0 Serrarens, 3-0 El Jebli, 3-1 El Messaoudi, 4-1 Serrarens, 5-1 El Jebli |
| 18 | 20/01/2019 | FC Emmen | PSV | 2-2 | 8.301 | Kamphuis | 0-1 De Jong, 0-2 Angelino, 1-2 en 2-2 Pedersen |
| 18 | 20/01/2019 | Ajax | sc Heerenveen | 4-4 | 50.000 | Gözübüyük | 1-0 Tadic, 1-1 Lammers, 2-1 Tadic, 3-1 Van Amers- foort (e.d.), 3-2 Lammers, 3-3 Van Bergen, 4-3 Huntelaar, 4-4 Pierie |
| 19 | 25/01/2019 | NAC Breda | ADO Den Haag | 1-1 | 18.547 | Van Boekel | 0-1 Lorenzen, 1-1 Kastaneer |
| 19 | 26/01/2019 | Heracles Almelo | PEC Zwolle | 0-2 | 10.667 | Lindhout | 0-1 Van Duinen, 0-2 Thy |
| 19 | 26/01/2019 | Excelsior | De Graafschap | 2-0 | 4.400 | Manschot | 1-0 Bruins, 2-0 El Hamdaoui |
| 19 | 26/01/2019 | VVV-Venlo | FC Emmen | 2-3 | 6.145 | Bax | 1-0 Opoku, 1-1 Bannink, 1-2 Arias, 2-2 Opoku, 2-3 Chacon |
| 19 | 26/01/2019 | PSV | FC Groningen | 2-1 | 33.900 | Higler | 1-0 en 2-0 Lozano, 2-1 Reis |
| 19 | 27/01/2019 | Fortuna Sittard | Vitesse | 2-1 | 8.123 | Perez | 0-1 Linssen, 1-1 Hutten, 2-1 Stokkers |
| 19 | 27/01/2019 | sc Heerenveen | AZ | 0-2 | 17.182 | S. Mulder | 0-1 Floranus (e.d.), 0-2 Idrissi |
| 19 | 27/01/2019 | FC Utrecht | Willem II | 0-1 | 17.256 | Kooij | 0-1 Crowley |
| 19 | 27/01/2019 | Feyenoord | Ajax | 6-2 | 47.500 | Makkelie | 0-1 Schöne, 1-1 Toornstra, 2-1 Berghuis, 2-2 Ziyech, 3-2 en 4-2 Van Persie, 5-2 Vilhena, 6-2 Ayoub |
| 20 | 01/02/2019 | De Graafschap | NAC Breda | 3-0 | 12.502 | Makkelie | 1-0 Burgzorg, 2-0 El Jebli, 3-0 Owusu |
| 20 | 02/02/2019 | Vitesse | sc Heerenveen | 2-2 | 15.342 | Vd Kerkhof | 0-1 Vlap, 1-1 Ali, 2-1 Linssen, 2-2 Lammers (pen) |
| 20 | 02/02/2019 | Willem II | FC Groningen | 1-2 | 12.633 | Martens | 0-1 Warmerdam, 0-2 Sierhuis, 1-2 Vrousai |
| 20 | 02/02/2019 | Ajax | VVV-Venlo | 6-0 | 52.000 | Lindhout | 1-0 Ziyech, 2-0 Dolberg, 3-0 Tadic, 4-0 Neres, 5-0 Huntelaar, 6-0 Van de Beek |
| 20 | 02/02/2019 | AZ | FC Emmen | 5-0 | 14.328 | Gözübüyük | 1-0 en 2-0 Koopmeiners (pen), 3-0 de Leeuw (e.d.), 4-0 Stengs, 5-0 Johnsen |
| 20 | 03/02/2019 | Excelsior | Feyenoord | 2-1 | 4.400 | Kamphuis | 0-1 Van Persie, 1-1 Messaouid, 2-1 Van der Meer |
| 20 | 03/02/2019 | PEC Zwolle | FC Utrecht | 4-3 | 13.024 | Kuipers | 0-1 Gustafson, 1-1 Van Crooy, 1-2 Letschert, 1-3 Bahebeck, 2-3 Lam, 3-3 (pen) en 4-3 Van Duinen R: Emanuelson, Bazoer (Utr) |
| 20 | 03/02/2019 | PSV | Fortuna Sittard | 5-0 | 34.400 | Blom | 1-0 Pereiro, 2-0 de Jong, 3-0 Gakpo, 4-0 en 5-0 De Jong |
| 20 | 03/02/2019 | ADO Den Haag | Heracles Almelo | 2-0 | 11.464 | S. Mulder | 1-0 en 2-0 Necid |
| 21 | 08/02/2019 | NAC Breda | AZ | 0-3 | 18.205 | Manschot | 0-1 en 0-2 Til, 0-3 Gudmundsson |
| 21 | 09/02/2019 | Heracles Almelo | Ajax | 1-0 | 12.080 | Higler | 1-0 Osman |
| 21 | 09/02/2019 | sc Heerenveen | PEC Zwolle | 1-1 | 19.822 | Makkelie | 1-0 Vlap, 1-1 Lam |
| 21 | 09/02/2019 | VVV-Venlo | Willem II | 2-1 | 6.134 | S. Mulder | 1-0 Mlapa, 1-1 Crowley (pen), 2-1 Mlapa |
| 21 | 09/02/2019 | Feyenoord | De Graafschap | 4-0 | 40.000 | Lindhout | 1-0 Vilhena, 2-0 Verdonk, 3-0 St. Juste, 4-0 Toornstra |
| 21 | 10/02/2019 | Fortuna Sittard | Excelsior | 4-1 | 8.479 | Bax | 1-0 en 2-0 Lamprou, 2-1 Messaoud, 3-1 Diemers, 4-1 Novakovich |
| 21 | 10/02/2019 | FC Groningen | Vitesse | 2-1 | 16.498 | Kuipers | 1-0 Sierhuis, 1-1 Darfalou, 2-1 El Hankouri |
| 21 | 10/02/2019 | FC Emmen | ADO Den Haag | 3-2 | 8.301 | Dieperink | 1-0 Bannink, 2-0 Braken, 2-1 Goossens, 2-2 Necid, 3-2 Jansen |
| 21 | 10/02/2019 | FC Utrecht | PSV | 2-2 | 19.005 | Van Boekel | 1-0 Van de Streek, 2-0 Kerk, 2-1 en 2-2 De Jong |
| 22 | 15/02/2019 | ADO Den Haag | PEC Zwolle | 1-0 | 12.253 | Kooij | 1-0 Troupée; R; Namli (PEC) |
| 22 | 16/02/2019 | AZ | VVV-Venlo | 3-0 | 14.675 | Vd Kerkhof | 1-0 Til, 2-0 Röseler, 3-0 M. Seuntjens |
| 22 | 16/02/2019 | sc Heerenveen | PSV | 2-2 | 23.522 | Kamphuis | 1-0 Van Bergen, 2-0 Vlap, 2-1 Pereiro, 2-2 Malen |
| 22 | 16/02/2019 | Heracles Almelo | Fortuna Sittard | 6-0 | 10.568 | Manschot | 1-0 en 2-0 Dalmau, 3-0 Drist, 4-0 Dalmau, 5-0 Peterson, 6-0 Dalmau |
| 22 | 16/02/2019 | Vitesse | Willem II | 3-2 | 14.168 | Lindhout | 1-0 Linssen, 2-0 Ødegaard, 2-1 Isak, 3-1 Clark, 3-2 Pavlidis |
| 22 | 17/02/2019 | Ajax | NAC Breda | 5-0 | 50.000 | Mulder | 1-0 Tadic (pen), 2-0 Dolberg, 3-0 Kastaneer (e.d.), 4-0 Tadic, 5-0 PAlmer-Brown |
| 22 | 17/02/2019 | Excelsior | FC Emmen | 2-1 | 4.200 | Higler | 0-1 De Leeuw, 1-1 Edwards, 2-1 Eckert |
| 22 | 17/02/2019 | FC Groningen | Feyenoord | 1-0 | 20.259 | Makkelie | 1-0 Van Beek (e.d.) |
| 22 | 17/02/2019 | De Graafschap | FC Utrecht | 0-1 | 12.464 | Blom | 0-1 Gustafson |
| 23 | 22/02/2019 | VVV-Venlo | Heracles Almelo | 0-1 | 6.534 | Blank | 0-1 Osman (pen) |
| 23 | 23/02/2019 | FC Utrecht | Excelsior | 0-0 | 18.676 | Gözübüyük | |
| 23 | 23/02/2019 | PEC Zwolle | De Graafschap | 0-3 | 13.823 | Martens | 0-1 Lam (e.d.), 0-2 Benschop, 0-3 Burgzorg |
| 23 | 23/02/2019 | Fortuna Sittard | sc Heerenveen | 2-4 | 8.523 | Van Boekel | 1-0 Lamprou, 2-0 Diemers, 2-1 Høegh, 2-2 V. Bergen, 2-3 (pen) en 2-4 Lammers; R: Rodriguez (For) |
| 23 | 23/02/2019 | NAC Breda | FC Groningen | 0-0 | 18.572 | Blom | |
| 23 | 24/02/2019 | ADO Den Haag | Ajax | 1-5 | 14.352 | Manschot | 1-0 El Khayati, 1-1 Van de Beek, 1-2 Tadic (pen), 1-3 Ziyech, 1-4 Dolberg, 1-5 Ziyech |
| 23 | 24/02/2019 | PSV | Feyenoord | 1-1 | 34.600 | Higler | 0-1 Jørgensen, 1-1 Lozano; R: Van Beek |
| 23 | 24/02/2019 | FC Emmen | Vitesse | 0-3 | 8.301 | Vd Graaf | 0-1 Dauda, 0-2 Ødegaard, 0-3 Foor |
| 23 | 24/02/2019 | Willem II | AZ | 2-1 | 12.423 | Dieperink | 1-0 Vrousai, 2-0 Crowley, 2-1 Til |
| 24 | 01/03/2019 | De Graafschap | ADO Den Haag | 1-1 | 12.498 | Kuipers | 0-1 Becker, 1-1 El Jabli |
| 24 | 02/03/2019 | Heracles Almelo | FC Utrecht | 1-5 | 11.200 | Bax | 0-1 Van de Streek, 0-1 Janssen, 1-2 Dalmau, 1-3 Kerk, 1-4 Gustafson (pen), 1-5 Bazoer (pen) R: Drost (Her) |
| 24 | 02/03/2019 | sc Heerenveen | Willem II | 4-2 | 17.882 | Vd Kerkhof | 1-0 Vlap, 2-0 (pen) en 3-0 Lammers, 3-1 Isak, 3-2 Pavlidis, 4-2 Rienstra; R: Meissner (Wil) |
| 24 | 02/03/2019 | Excelsior | PSV | 0-2 | 4.400 | Makkelie | 0-1 en 0-2 Bergwijn |
| 24 | 02/03/2019 | Vitesse | NAC Breda | 4-1 | 12.757 | Kooij | 0-1 Korte, 1-1 Buitink, 2-1 Van der Werff, 3-1 Büttner, 4-1 Bero; R: Klomp (NAC) |
| 24 | 03/03/2019 | AZ | Fortuna Sittard | 4-2 | 13.823 | Lindhout | 1-0 Koopmeiners (pen), 1-1 Lamprou, 1-2 Novakovich, 2-2 Til, 3-2 Idrissi, 4-2 Koopmeiners |
| 24 | 03/03/2019 | FC Groningen | VVV-Venlo | 3-2 | 16.757 | Gözübüyük | 0-1 Post, 1-1 en 2-1 Mahi (pen), 2-2 Mlapa, 3-2 Bel Hassani; R: Rutten (VVV) |
| 24 | 03/03/2019 | Feyenoord | FC Emmen | 4-0 | 30.000 | Kamphuis | 1-0 , 2-0 en 3-0 Van Persie, 4-0 Berghuis |
| 25 | 08/03/2019 | FC Utrecht | FC Groningen | 0-0 | 18.146 | Kuipers | |
| 25 | 09/03/2019 | VVV-Venlo | Excelsior | 1-0 | 6.382 | Blom | 1-0 Opoku |
| 25 | 09/03/2019 | PSV | NAC Breda | 2-0 | 34.300 | Gözübüyük | 1-0 De Jong, 2-0 Malen |
| 25 | 09/03/2019 | ADO Den Haag | sc Heerenveen | 2-3 | 13.118 | Martens | 0-1 Vlap, 1-1 Necid, 1-2 Vlap, 1-3 Lammers, 2-3 El Khayati |
| 25 | 09/03/2019 | Willem II | De Graafschap | 3-2 | 12.796 | Blank | 1-0 en 2-0 Isik, 2-1 Straalman, 3-1 Lewis, 3-2 El Jebli (pen) |
| 25 | 10/03/2019 | PEC Zwolle | AZ | 0-0 | 13.954 | Makkelie | |
| 25 | 10/03/2019 | Vitesse | Feyenoord | 1-1 | 17.208 | Manschot | 0-1 Kökcü, 1-1 Dauda |
| 25 | 10/03/2019 | FC Emmen | Heracles Almelo | 1-1 | 8.185 | Mulder | 0-1 Dalmau, 1-1 Braken; R: Breukers (Her) |
| 25 | 10/03/2019 | Ajax | Fortuna Sittard | 4-0 | 52.000 | Kamphuis | 1-0 Tadic, 2-0 en 3-0 Neres, 4-0 Tadic |
| 24 | 13/03/2019 | Ajax | PEC Zwolle | 2-1 | 50.000 | Lindhout | 1-0 Tadic, 1-1 Van Crooy, 2-1 Blind R: Van Crooy (PEC) |
| 26 | 15/03/2019 | Fortuna Sittard | FC Emmen | 3-1 | 10.232 | Makkelie | 1-0 Lukic (e.d.), 2-0 Semedo, 3-0 Novakovich, 3-1 Niemeijer; R: Bijl (Emm) |
| 26 | 16/03/2019 | sc Heerenveen | De Graafschap | 0-3 | 19.020 | Bax | 0-1 Benschop, 0-2 Vet, 0-3 Burgzorg |
| 26 | 16/03/2019 | Feyenoord | Willem II | 2-3 | 37.000 | Van Boekel | 1-0 Berghuis, 1-1 Heerkens, 2-1 Botteghin, 2-2 Lewis, 2-3 Isak |
| 26 | 16/03/2019 | NAC Breda | FC Utrecht | 0-4 | 18.613 | Kamphuis | 0-1 Bahebeck, 0-2 Gustafson (pen), 0-3 Janssen, 0-4 Bahebeck |
| 26 | 16/03/2019 | Heracles Almelo | Vitesse | 3-2 | 11.086 | Kuipers | 1-0 Dalmau, 1-1 Foor, 2-1 Dalmau, 2-2 Bero (pen), 3-2 Van den Buijs; R: Clark (Vit) |
| 26 | 17/03/2019 | VVV-Venlo | PSV | 0-1 | 8.000 | Manschot | 0-1 Lozano |
| 26 | 17/03/2019 | AZ | Ajax | 1-0 | 17.026 | Gözübüyük | 1-0 Til |
| 26 | 17/03/2019 | FC Groningen | ADO Den Haag | 1-0 | 17.291 | Higler | 1-0 Immers (e.d.) |
| 26 | 17/03/2019 | Excelsior | PEC Zwolle | 0-2 | 4.093 | Mulder | 0-1 Ehizibue, 0-2 Namli |
| 27 | 30/03/2019 | Willem II | Fortuna Sittard | 3-2 | 14.270 | Martens | 0-1 Novakovich, 1-1 Isak (pen), 1-2 Ninaj, 2-2 en 3-2 Isak (pen); R: Balic (For) |
| 27 | 30/03/2019 | ADO Den Haag | Vitesse | 3-3 | 13.721 | Mulder | 1-0 Becker, 1-1 en 1-2 Buitink, 2-2 Immers, 2-3 Buitink, 3-3 Immers |
| 27 | 30/03/2019 | De Graafschap | Heracles Almelo | 1-2 | 12.502 | Higler | 1-0 Benschop, 1-1 Kuwas, 1-2 Duarte |
| 27 | 30/03/2019 | sc Heerenveen | Excelsior | 1-0 | 18.021 | Lindhout | 1-0 Van Amersfoort |
| 27 | 30/03/2019 | AZ | FC Groningen | 1-0 | 15.404 | Van Boekel | 1-0 Vlaar |
| 27 | 31/03/2019 | NAC Breda | VVV-Venlo | 1-1 | 17.946 | Vd Graaf | 0-1 Mlapa, 1-1 Leigh; R: El Allouchi (NAC) |
| 27 | 31/03/2019 | FC Utrecht | Feyenoord | 3-2 | 21.758 | Gözübüyük | 1-0 Emanuelson, 2-0 Van de Streek, 2-1 Larsson, 2-2 Van Persie, 3-2 Letschert |
| 27 | 31/03/2019 | PEC Zwolle | FC Emmen | 3-0 | 13.721 | Kamphuis | 1-0 Van Crooy, 2-0 en 3-0 Thy |
| 27 | 31/03/2019 | Ajax | PSV | 3-1 | 52.669 | Kuipers | 1-0 Schwaab (e.d.), 1-1 De Jong, 2-1 Tadic (pen), 3-1 Neres; R: Mazraoui (Aja) |
| 28 | 02/04/2019 | Vitesse | AZ | 2-2 | 14.162 | Lindhout | 0-1 Vlaar, 0-2 Koopmeiners, 1-2 Bero, 2-2 Buitink |
| 28 | 02/04/2019 | Heracles Almelo | Willem II | 3-4 | 10.442 | Vd Eijk | 0-1 en 0-2 Isak, 0-3 Pavlidis, 1-3 Kuwas, 2-3 Konings, 2-4 Vrousai, 3-4 Dalmau |
| 28 | 02/04/2019 | FC Groningen | De Graafschap | 1-0 | 18.008 | Kooij | 1-0 Gladon |
| 28 | 03/04/2019 | VVV-Venlo | FC Utrecht | 2-6 | 6.723 | Dieperink | 1-0 Opoku, 1-1 Bazoer, 2-1 Joosten, 2-2 Bazoer, 2-3 Post (e.d.), 2-4 Klaiber, 2-5 Van de Streek, 2-6 Kramer |
| 28 | 03/04/2019 | Excelsior | NAC Breda | 1-2 | 4.400 | Vd Kerkhof | 1-0 El Hamdaoui, 1-1 Korte, 1-2 Koch |
| 28 | 03/04/2019 | Fortuna Sittard | ADO Den Haag | 0-0 | 8.125 | Kamphuis | R: Rodriquez (For) |
| 28 | 03/04/2019 | FC Emmen | Ajax | 2-5 | 8.301 | Mulder | 0-1 Van de Beek, 0-2 Blind, 0-3 Neres, 0-4 Huntelaar, 0-5 Neres, 1-5 Tagliafico (e.d.), 2-5 Arias |
| 28 | 04/04/2019 | PSV | PEC Zwolle | 4-0 | 34.000 | Van Boekel | 1-0 De Jong, 2-0 Bergwijn, 3-0 De Jong, 4-0 Malen |
| 28 | 04/04/2019 | Feyenoord | sc Heerenveen | 3-0 | 25.000 | Kuipers | 1-0 Jørgensen, 2-0 Berghuis, 3-0 Vilhena |
| 29 | 06/04/2019 | FC Groningen | Excelsior | 1-0 | 17.456 | Bax | 1-0 Gladon |
| 29 | 06/04/2019 | ADO Den Haag | FC Utrecht | 5-0 | 13.022 | Lindhout | 1-0 Immers, 2-0 Meijers, 3-0 Bakker, 4-0 Necid, 5-0 Immers |
| 29 | 06/04/2019 | Willem II | Ajax | 1-4 | 14.700 | Makkelie | 0-1 Van de Beek, 1-1 Isak (pen), 1-2 Heerkens (e.d.), 1-3 Veltman, 1-4 Ziyech |
| 29 | 06/04/2019 | De Graafschap | AZ | 1-1 | 12.503 | Kamphuis | 0-1 Til, 1-1 Bizot (e.d.) |
| 29 | 06/04/2019 | Heracles Almelo | NAC Breda | 1-0 | 10.530 | Martens | 1-0 Peterson |
| 29 | 07/04/2019 | FC Emmen | sc Heerenveen | 2-0 | 8.301 | Vd Kerkhof | 1-0 en 2-0 Cavlan |
| 29 | 07/04/2019 | PEC Zwolle | Fortuna Sittard | 5-0 | 13.334 | Higler | 1-0 Van Crooy, 2-0 Namli, 3-0 Thy, 4-0 Van Duinen, 5-0 Thy; R: Ninaj (For) |
| 29 | 07/04/2019 | VVV-Venlo | Feyenoord | 0-3 | 8.000 | Mulder | 0-1 Larsson, 0-2 Jørgensen, 0-3 Malacia |
| 29 | 07/04/2019 | Vitesse | PSV | 3-3 | 21.248 | Gözübüyük | 1-0 Serero, 1-1 Lozano (pen), 2-1 Ødegaard, 2-2 De Jong, 3-2 Matavz, 3-3 Lozano (pen) R: Van der Werf (Vit) |
| 30 | 12/04/2019 | NAC Breda | FC Emmen | 1-1 | 18.422 | Makkelie | 0-1 Slagveer, 1-1 Palmer-Brown |
| 30 | 13/04/2019 | AZ | ADO Den Haag | 2-3 | 15.034 | Kuipers | 0-1 en 0-2 Falkenburg, 1-2 en 2-2 Gudmundsson, 2-3 Becker |
| 30 | 13/04/2019 | Feyenoord | Heracles Almelo | 2-1 | 35.000 | Kamphuis | 1-0 Berghuis, 1-1 Drost, 2-1 Berghuis (pen) R: Jørgensen (Fey) |
| 30 | 13/04/2019 | Fortuna Sittard | VVV-Venlo | 1-1 | 9.511 | Bax | 1-0 Novakovich, 1-1 Grot |
| 30 | 14/04/2019 | Willem II | PEC Zwolle | 2-0 | 12.947 | Dieperink | 1-0 Dankerlui, 2-0 Isak |
| 30 | 14/04/2019 | PSV | De Graafschap | 2-1 | 34.500 | Lindhout | 0-1 Burgzorg, 1-1 Bergwijn (pen), 2-1 De Jong |
| 30 | 14/04/2019 | sc Heerenveen | FC Groningen | 1-1 | 21.056 | Nijhuis | 1-0 Van Amersfoort, 1-1 Gladon |
| 30 | 14/04/2019 | FC Utrecht | Vitesse | 0-0 | 22.064 | Higler | |
| 30 | 13/04/2019 | Ajax | Excelsior | 6-2 | 52.000 | Van Boekel | 1-0 Huntelaar, 2-0 Tadic, 3-0 Huntelaar, 3-1 El Hamdaoui, 4-1 Tadic, 5-1 Huntelaar, 6-1 Dolberg, 6-2 Fortes |
| 31 | 19/04/2019 | Heracles Almelo | sc Heerenveen | 2-1 | 11.586 | Kooij | 1-0 Kuwas (pen), 1-1 Lammers (pen), 2-1 Dalmau |
| 31 | 20/04/2019 | FC Emmen | FC Utrecht | 2-0 | 8.269 | Martens | 1-0 De Leeuw, 2-0 Veendorp |
| 31 | 20/04/2019 | Feyenoord | AZ | 2-1 | 45.000 | Nijhuis | 0-1 Seuntjens, 1-1 Malacia, 2-1 Van Persie |
| 31 | 20/04/2019 | Vitesse | PEC Zwolle | 4-1 | 15.387 | Kuipers | 1-0 Linssen, 1-1 Thy, 2-1 Linssen, 3-1 Dauda, 4-1 Linssen; R: Büttner (Vit) |
| 31 | 20/04/2019 | VVV-Venlo | De Graafschap | 4-1 | 6.545 | Gözübüyük | 0-1 Narsingh, 1-1 Seuntjens, 2-1 Mlapa, 3-1 Grot, 4-1 Rutten |
| 31 | 21/04/2019 | Excelsior | Willem II | 1-1 | 4.140 | Lindhout | 0-1 Tapia, 1-1 El Hamdaoui |
| 31 | 21/04/2019 | Fortuna Sittard | NAC Breda | 2-1 | 10.266 | Van Boekel | 1-0 (pen) en 2-0 Diemers, 2-1 Te Vrede |
| 31 | 21/04/2019 | FC Groningen | Ajax | 0-1 | 22.288 | Higler | 0-1 Huntelaar; R: Huntelaar (Aja) |
| 31 | 21/04/2019 | PSV | ADO Den Haag | 3-1 | 34.300 | Makkelie | 1-0 Dumfries, 2-0 De Jong, 2-1 Necid, 3-1 Malen |
| 32 | 23/04/2019 | De Graafschap | FC Emmen | 1-0 | 12.501 | Kuipers | 1-0 Serrarens |
| 32 | 23/04/2019 | sc Heerenveen | VVV-Venlo | 2-2 | 17.450 | Dieperink | 1-0 Vlap, 1-1 Grot, 2-1 Vlap, 2-2 Steijn |
| 32 | 23/04/2019 | AZ | Heracles Almelo | 2-1 | 13.521 | Mulder | 1-0 Stengs, 1-1 Kuwas, 2-1 Gudmundsson |
| 32 | 23/04/2019 | Ajax | Vitesse | 4-2 | 52.000 | Kamphuis | 1-0 Ziyech, 2-0 Tadic (pen), 3-0 De L:igt, 3-1 Foor, 4-1 Tadic, 4-2 Darfalou; R: Bero (Vit) |
| 32 | 24/04/2019 | NAC Breda | Feyenoord | 0-4 | 18.473 | Lindhout | 0-1 St Juste, 0-2 Vente, 0-3 en 0-4 Toornstra |
| 32 | 24/04/2019 | FC Utrecht | Fortuna Sittard | 2-1 | 19.295 | Vd Graaf | 1-0 Kerk, 1-1 Balic, 2-1 Kerk |
| 32 | 24/04/2019 | PEC Zwolle | FC Groningen | 3-2 | 13.942 | Vd Kerkhof | 0-1 Sierhuis, 1-1 Thy, 1-2 Gladon, 2-2 Van Polen, 3-2 Thy; gestaakt op 24/4. uitgespeeld op 29/4 bij een stand van 1-2. |
| 32 | 25/04/2019 | ADO Den Haag | Excelsior | 3-1 | 13.392 | Manschot | 1-0 El Khayati, 1-1 Fortes, 2-1 Bakker, 3-1 Becker |
| 32 | 25/04/2019 | Willem II | PSV | 0-3 | 14.700 | Higler | 0-1 Malen, 0-2 De Jong, 0-3 Bergwijn |
| 34 | 12/05/2019 | sc Heerenveen | NAC Breda | 2-1 | 18.500 | Higler | 1-0 Lammers, 1-1 Koch, 2-1 Van Bergen |
| 34 | 12/05/2019 | Feyenoord | ADO Den Haag | 0-2 | 45.000 | Mulder | 0-1 Falkenburg, 0-2 Becker |
| 34 | 12/05/2019 | AZ | PSV | 1-0 | 16.555 | Makkelie | 1-0 Til |
| 34 | 12/05/2019 | Willem II | FC Emmen | 2-3 | 13.800 | Kamphuis | 1-0 Pavlidis, 2-0 Isak, 2-1 Slagveer, 2-2 Ben Moussa, 2-3 De Leeuw |
| 34 | 12/05/2019 | PEC Zwolle | VVV-Venlo | 2-4 | 13.189 | Vd Eijk | 1-0, 1-1 en 1-2 Mlapa, 1-3 Van Ooijen, 1-4 Mlapa, 2-4 Elbers |
| 34 | 12/05/2019 | Ajax | FC Utrecht | 4-1 | 53.520 | Van Boekel | 0-1 Boussaid, 1-1 Huntelaar, 2-1 Van de Beek, 3-1 en 4-1 (pen) Tadic |
| 34 | 12/05/2019 | Heracles Almelo | Excelsior | 4-5 | 11.485 | Gözübüyük | 0-1 Omarsson, 1-1 Dalmau, 1-2 Omarsson, 2-2 en 3-2 Dalmau, 4-2 Duarte, 4-3 Mattheij, 4-4 Eckert, 4-5 Omarsson |
| 34 | 12/05/2019 | Vitesse | De Graafschap | 6-1 | 16.250 | Nijhuis | 1-0 Straalman (e.d.), 2-0 en 3-0 Buitink, 4-0 Ødegaard (pen), 5-0 Darfalu, 5-1 El Jebli, 6-1 Musaba |
| 34 | 12/05/2019 | FC Groningen | Fortuna Sittard | 3-0 | 19.738 | Manschot | 1-0 Gladon, 2-0 Doan, 3-0 Memisevic |
| 33 | 15/05/2019 | FC Utrecht | sc Heerenveen | 3-1 | 18.646 | Bax | 0-1 Rienstra, 1-1 Janssen, 2-1 Van de Streek, 3-1 Dessers |
| 33 | 15/05/2019 | NAC Breda | PEC Zwolle | 0-0 | 14.216 | Kamphuis | |
| 33 | 15/05/2019 | PSV | Heracles Almelo | 3-1 | 34.200 | Nijhuis | 0-1 Konings, 1-1 Droste (e.d.), 2-1 Viergever, 3-1 Malen |
| 33 | 15/05/2019 | Fortuna Sittard | Feyenoord | 1-4 | 12.300 | Gözübüyük | 0-1 Kökcü, 1-1 Smeets, 1-2 en 1-3 Jørgensen, 1-4 Berghuis; R; Heerings (For) |
| 33 | 15/05/2019 | Excelsior | AZ | 4-2 | 3.811 | Higler | 1-0 Fortes, 1-1 Koopmeiners, 2-1 Van Rhijn (e.d.), 3-1 Bruins, 4-1 Omarsson, 4-2 Johnsen |
| 33 | 15/05/2019 | De Graafschap | Ajax | 1-4 | 12.600 | Makkelie | 0-1 Schöne, 1-1 El Jebli, 1-2 Tagliafico, 1-3 (pen) en 1-4 Tadic |
| 33 | 15/05/2019 | VVV-Venlo | Vitesse | 1-3 | 6.512 | Lindhout | 0-1 Karavaev, 0-2 Ødegaard, 1-2 Van Ooijen, 1-3 Bero |
| 33 | 15/05/2019 | ADO Den Haag | Willem II | 6-2 | 13.128 | Martens | 0-1 Dankerlui, 1-1 El Khayati, 1-2 Pavlidis, 2-2 Kanon, 3-2 El Khayati (pen), 4-2 Necid, 5-2 Immers, 6-2 Necid; R; Dankerlui (Wil) |
| 33 | 15/05/2019 | FC Emmen | FC Groningen | 1-0 | 8.301 | Van Boekel | 1-0 Chacon |
Play offs voor Europa League
| 1e ronde | ||||||
| 18/05/2019 | Heracles Almelo | FC Utrecht | 0-2 | 8.322 | Mulder | 0-1 Gustafson (pen), 0-2 Dessers |
| 18/05/2019 | FC Groningen | Vitesse | 2-1 | 16.783 | Higler | 1-0 Mahi, 2-0 memisevic (pen), 2-1 Clark |
| 21/05/2019 | FC Utrecht | Heracles Almelo | 3-0 | 11.233 | Lindhout | 1-0 Gustafson (pen), 2-0 en 3-0 Bahebeck |
| 21/05/2019 | Vitesse | FC Groningen | 3-1 | 9.756 | Nijhuis | 1-0 Ødegaard, 2-0 en 3-0 Matavz, 3-1 Sierhuis |
| 2e ronde | ||||||
| 24/05/2019 | FC Utrecht | Vitesse | 1-1 | 18.328 | Manschot | 1-0 Van de Streek, 1-1 Matavz |
| 28/05/2019 | Vitesse | FC Utrecht | 0-2 | 16.799 | Lindhout | 0-1 Dessers, 0-2 Gustafson; R: Dauda |
Play offs voor promotie/degradatie
| 1e ronde | ||||||
| 10/05/2019 | NEC | RKC Waalwijk | 2-0 | 8.261 | Bax | 1-0 Ndayishimiye, 2-0 Bruijn |
| 10/05/2019 | SC Cambuur | Almere City FC | 2-2 | 6.843 | Lindhout | 0-1 Bansabouh, 1-1 Mbende, 1-2 Meijer, 2-2 Ciganiks |
| 14/05/2019 | RKC Waalwijk | NEC | 3-0 | 3.249 | Kamphuis | 1-0 Seys, 2-0 Spierings, 3-0 Bilate |
| 14/05/2019 | Almere City FC | SC Cambuur | 1-2 | 2.569 | Vd Kerkhof | 0-1 Robertha, 0-2 Bansabouh (e.d.), 1-2 Vossebelt |
| 2e ronde | ||||||
| 19/05/2019 | RKC Waalwijk | Excelsior | 2-1 | 4.319 | Martens | 1-0 Bilate, 1-1 Fortes, 2-1 Gaari |
| 19/05/2019 | Go Ahead Eagles | FC Den Bosch | 2-2 | 9.467 | Kamphuis | 0-1 Van der Sande, 1-1 Lelieveld, 1-2 Brouwers, 2-2 Navratil |
| 19/05/2019 | TOP Oss | Sparta Rotterdam | 0-2 | 4.346 | Bax | 0-1 en 0-2 Harroui |
| 19/05/2019 | SC Cambuur | De Graafschap | 1-1 | 8.542 | Manschot | 0-1 Narsingh, 1-1 Maulun; R: Mbende (Cam) |
| 22/05/2019 | Excelsior | RKC Waalwijk | 1-1 | 4.400 | Vd Graaf | 0-1 Spierings, 1-1 Omarsson; R: Spierings (RKC) |
| 22/05/2019 | FC Den Bosch | Go Ahead Eagles | 0-1 | 6.900 | Vd Kerkhof | 0-1 Veldmate |
| 22/05/2019 | Sparta Rotterdam | TOP Oss | 3-0 | 10.020 | Makkelie | 1-0 Vriends, 2-0 en 3-0 Ache |
| 22/05/2019 | De Graafschap | SC Cambuur | 2-0 | 10.611 | Mulder | 1-0 en 2-0 (pen) Benschop |
| 3e ronde | ||||||
| 25/05/2019 | RKC Waalwijk | Go Ahead Eagles | 0-0 | 6.182 | Lindhout | |
| 25/05/2019 | Sparta Rotterdam | De Graafschap | 1-2 | 10.031 | Kamphuis | 1-0 Auassar, 1-1 Bahoui, 1-2 El Jebli (pen); R: Vriends (Spa) |
| 28/05/2019 | Go Ahead Eagles | RKC Waalwijk | 4-5 | 9.800 | Higler | 0-1 Hansson (pen), 0-2 Spierings, 1-2 Veldmate (pen), 2-2 Van der Venne, 3-2 Bakx, 3-3 Mulder, 4-3 Langedijk, 4-4 Spierings, 4-5 Bilate (pen) |
| 28/05/2019 | De Graafschap | Sparta Rotterdam | 0-2 | 12.600 | Blom | 0-1 Dervisoglu, 0-2 Auassar |
RKC Waalwijk en Sparta Rotterdam gepromoveerd; Excelsior en De Graafschap gedegradeerd
Topscorers
| 1 | Luuk de Jong | PSV | 28 |
| 2 | Dusan Tadic | Ajax | 28 |
| 3 | Adrián Dalmau | Heracles Almelo | 19 |
| 4 | Hirving Lozano | PSV | 17 |
| 5 | Abdenasser El Khayati | ADO Den Haag | 17 |
| 6 | Robin van Persie | Feyenoord | 16 |
| 7 | Klaas-Jan Huntelaar | Ajax | 16 |
| 8 | Hakim Ziyech | Ajax | 16 |
| 9 | Sam Lammers | sc Heerenveen | 16 |
| 10 | Michel Vlap | sc Heerenveen | 16 |
Het seizoen begint dramatisch voor de Nederlandse topclubs. Ajax en PSV stranden al in de voorronden van het Europese voetbal tegen respectievelijk Rosenborg en Osijek. Opnieuw een duidelijk signaal dat het Nederlandse voetbal er beroerd voor staat. Dat blijkt later ook als Feyenoord geen potten kan breken in de Champions League.
PSV is wel net op tijd in vorm voor de start van de competitie en neemt direct het heft in handen om dat niet meer los te laten. Feyenoord worstelt na de titel met zijn vorm en bij Ajax gaat alles fout na een succesvol seizoen onder Peter Bosz, met als dieptepunt het noodlot dat Abdelhak Nouri treft in een oefenwedstrijd tegen Werder Bremen op 8 juli. Hartfalen zorgt voor blijvende hersenschade bij het dan 20-jarige talent. Het blijft het hele seizoen als een deken over Ajax liggen.
PSV is uiteindelijk al vroeg zeker van de derde landstitel in vier seizoenen. De Eindhovenaren zijn het hele seizoen de meest degelijke en constante ploeg, zonder dat het vaak tot flitsend spel komt. Ondanks het rampseizoen wordt Ajax uiteindelijk tweede. AZ maakt voetballend misschien wel de meeste indruk, maar bouwt een complex op als het gaat om spelen tegen de topclubs: alle zes ontmoetingen met de “PAF”-clubs gaan verloren. Vitesse pakt in de play-offs verrassend het laatste Europese ticket.
Minstens zo verrassend is de degradatie van grootmacht FC Twente. De club, die twee jaar eerder ternauwernood degradatie van achter de grote tafel wist te voorkomen, kent een dramatisch seizoen. Met een onsamenhangende selectie en paniekerig beleid (zowel René Hake als Gert-Jan Verbeek worden ontslagen) presteert het team, dat nog altijd over een subtopbegroting beschikt, ondermaats en eindigt als laatste. Via de play-offs degraderen nog eens twee van oudsher grote clubs (Sparta en Roda JC).
Feyenoord, dat zich opricht in de laatste fase van de competitie pakt met de KNVB-Bekerwinst toch nog een prijs. Dat gaat ten koste van AZ, dat ook de zevende wedstrijd tegen een traditionele topclub verliest.
Uitslagenmatrix
| ADO | AJA | AZ | EXC | FEY | GRO | HEE | HER | NAC | PEC | PSV | ROD | SPA | TWE | UTR | VIT | VVV | WIL | |
| ADO Den Haag | * | 1-1 | 0-3 | 1-2 | 2-2 | 0-3 | 1-2 | 4-1 | 0-2 | 4-0 | 3-3 | 3-2 | 1-0 | 2-1 | 0-3 | 1-0 | 1-1 | 2-1 |
| Ajax | 0-0 | * | 3-0 | 3-1 | 2-0 | 3-1 | 4-1 | 1-0 | 3-1 | 3-0 | 3-0 | 5-1 | 4-0 | 2-1 | 1-2 | 1-2 | 4-1 | 3-1 |
| AZ | 2-0 | 1-2 | * | 0-2 | 0-4 | 3-2 | 3-1 | 5-0 | 2-1 | 6-0 | 2-3 | 2-2 | 2-1 | 2-0 | 3-0 | 4-3 | 0-0 | 3-2 |
| Excelsior | 1-2 | 1-2 | 1-2 | * | 0-1 | 2-0 | 1-2 | 2-2 | 0-0 | 1-2 | 1-2 | 1-0 | 1-1 | 0-0 | 2-2 | 0-3 | 0-2 | 2-1 |
| Feyenoord | 3-1 | 1-4 | 2-1 | 5-0 | * | 3-0 | 1-1 | 1-0 | 0-2 | 0-0 | 1-3 | 5-1 | 3-1 | 2-1 | 3-1 | 1-0 | 1-1 | 5-0 |
| FC Groningen | 0-0 | 1-2 | 1-1 | 4-0 | 0-2 | * | 3-3 | 3-3 | 1-1 | 2-0 | 3-3 | 2-1 | 4-0 | 1-0 | 2-1 | 4-2 | 1-1 | 0-1 |
| sc Heerenveen | 2-0 | 0-4 | 1-2 | 0-1 | 2-3 | 1-1 | * | 1-1 | 1-0 | 1-2 | 2-0 | 1-1 | 2-1 | 1-0 | 2-2 | 0-4 | 2-2 | 2-0 |
| Heracles Almelo | 1-1 | 2-1 | 0-3 | 2-2 | 2-4 | 2-1 | 1-2 | * | 2-1 | 2-1 | 1-2 | 2-1 | 3-2 | 2-1 | 1-1 | 1-1 | 3-0 | 1-0 |
| NAC Breda | 0-1 | 0-8 | 1-3 | 3-1 | 2-1 | 2-1 | 3-0 | 6-1 | * | 0-2 | 1-4 | 0-1 | 2-2 | 1-2 | 3-1 | 1-0 | 0-1 | 1-2 |
| PEC Zwolle | 2-0 | 0-1 | 1-1 | 1-1 | 3-4 | 3-2 | 3-2 | 2-1 | 1-0 | * | 0-1 | 4-2 | 2-0 | 2-0 | 1-1 | 1-2 | 1-1 | 0-1 |
| PSV | 3-0 | 3-0 | 3-2 | 1-0 | 1-0 | 0-0 | 2-2 | 3-0 | 5-1 | 4-0 | * | 2-0 | 1-0 | 4-3 | 3-0 | 2-1 | 3-0 | 4-0 |
| Roda JC | 2-3 | 2-4 | 0-1 | 2-1 | 1-1 | 2-2 | 2-1 | 0-3 | 1-0 | 3-2 | 2-2 | * | 0-2 | 1-1 | 1-4 | 1-3 | 0-1 | 1-3 |
| Sparta | 2-1 | 2-5 | 0-2 | 2-3 | 0-7 | 2-1 | 0-0 | 2-5 | 2-1 | 1-1 | 1-2 | 1-2 | * | 1-0 | 1-3 | 0-1 | 3-2 | 1-0 |
| FC Twente | 2-3 | 3-3 | 0-4 | 1-3 | 1-3 | 1-1 | 0-4 | 2-1 | 1-1 | 2-0 | 0-2 | 3-0 | 1-1 | * | 4-0 | 1-1 | 1-2 | 2-2 |
| FC Utrecht | 3-3 | 0-0 | 1-1 | 3-1 | 1-1 | 1-1 | 3-1 | 1-1 | 2-2 | 2-1 | 1-7 | 2-0 | 1-0 | 3-1 | * | 5-1 | 1-0 | 2-0 |
| Vitesse | 2-0 | 3-2 | 1-2 | 1-2 | 3-1 | 2-0 | 1-1 | 0-0 | 4-1 | 0-0 | 2-4 | 0-3 | 7-0 | 5-0 | 1-1 | * | 1-1 | 2-2 |
| VVV-Venlo | 0-2 | 0-2 | 0-2 | 2-3 | 1-0 | 1-1 | 0-2 | 3-1 | 0-0 | 1-1 | 2-5 | 1-4 | 3-0 | 0-0 | 0-1 | 2-2 | * | 3-3 |
| Willem II | 1-2 | 1-3 | 0-2 | 1-2 | 1-5 | 1-1 | 1-2 | 3-1 | 1-1 | 2-3 | 5-0 | 1-0 | 2-2 | 3-1 | 3-2 | 2-2 | 3-0 | * |
Eindstand
| 1 | PSV * ** | 34 | 26 | 5 | 3 | 83 | 87 | 39 | +48 | 33.132 |
| 2 | Ajax ** | 34 | 25 | 4 | 5 | 79 | 89 | 33 | +56 | 44.453 |
| 3 | AZ *** | 34 | 22 | 5 | 7 | 71 | 72 | 38 | +34 | 14.643 |
| 4 | Feyenoord *** | 34 | 20 | 6 | 8 | 66 | 76 | 39 | +37 | 45.588 |
| 5 | FC Utrecht + | 34 | 14 | 12 | 8 | 54 | 58 | 53 | +5 | 18.971 |
| 6 | Vitesse + *** | 34 | 13 | 10 | 11 | 49 | 63 | 47 | +16 | 15.944 |
| 7 | ADO Den Haag + | 34 | 13 | 8 | 13 | 47 | 45 | 53 | −8 | 11.537 |
| 8 | sc Heerenveen + | 34 | 12 | 10 | 12 | 46 | 48 | 53 | −5 | 19.830 |
| 9 | PEC Zwolle | 34 | 12 | 8 | 14 | 44 | 42 | 54 | −12 | 13.048 |
| 10 | Heracles Almelo | 34 | 11 | 9 | 14 | 42 | 50 | 64 | −14 | 10.580 |
| 11 | Excelsior | 34 | 11 | 7 | 16 | 40 | 41 | 56 | −15 | 4.201 |
| 12 | FC Groningen | 34 | 8 | 14 | 12 | 38 | 50 | 50 | 0 | 17.198 |
| 13 | Willem II | 34 | 10 | 7 | 17 | 37 | 50 | 63 | −13 | 12.420 |
| 14 | NAC Breda | 34 | 9 | 7 | 18 | 34 | 41 | 57 | −16 | 18.404 |
| 15 | VVV-Venlo | 34 | 7 | 13 | 14 | 34 | 35 | 54 | −19 | 6.745 |
| 16 | Roda JC Kerkrade ^^ | 34 | 8 | 6 | 20 | 30 | 42 | 69 | −27 | 12.329 |
| 17 | Sparta Rotterdam ^^ | 34 | 7 | 6 | 21 | 27 | 34 | 75 | −41 | 10.138 |
| 18 | FC Twente ^ | 34 | 5 | 9 | 20 | 24 | 37 | 63 | −26 | 24.394 |
Wedstrijden
| R: | Datum: | Thuis: | Uit: | Sc.: | Ts.: | Ar.: | Details: |
|---|---|---|---|---|---|---|---|
| 1 | 11/08/2017 | ADO Den Haag | FC Utrecht | 0-3 | 12.123 | Janssen | 0-1 Dessers, 0-2 Van de Streek, 0-3 Dessers |
| 1 | 12/08/2017 | VVV-Venlo | Sparta Rotterdam | 3-0 | 5.832 | Kamphuis | 1-0 Leemans, 2-0 Tissoudali, 3-0 Van Crooy R: Chabot (Spa) |
| 1 | 12/08/2017 | PSV | AZ | 3-2 | 30.000 | Kuipers | 0-1 Dos Santos, 1-1 Lozano, 2-1 Pereiro, 3-1 Van Ginkel, 3-2 Weghorst (pen) |
| 1 | 12/08/2017 | Heracles Almelo | Ajax | 2-1 | 12.080 | Blom | 0-1 Ziyech, 1-1 Gladon, 2-1 Kuwas |
| 1 | 12/08/2017 | Vitesse | NAC Breda | 4-1 | 13.921 | Mulder | 1-0 Bruns, 2-0 Linssen, 3-0 Matavz, 3-1 Ambrose, 4-1 Rashica |
| 1 | 13/08/2017 | PEC Zwolle | Roda JC Kerkrade | 4-2 | 13.000 | Nijhuis | 0-1 Gustrafson, 1-1 Marcellis, 2-1 Auassar (e.d.), 2-2 Gustafson (pen), 3-2 Saymak, 4-1 Van Polen |
| 1 | 13/08/2017 | Feyenoord | FC Twente | 2-1 | 47.500 | Gözübüyük | 1-0 Jørgensen, 1-1 F. Jensen, 2-1 Berghuis |
| 1 | 13/08/2017 | Willem II | Excelsior | 1-2 | 12.800 | Manschot | 0-1 Wellenreuther (e.d.), 0-2 El Azouzzi, 1-2 Sol |
| 1 | 13/08/2017 | FC Groningen | sc Heerenveen | 3-3 | 19.255 | Van Boekel | 0-1 Thorsby, 0-2 Ghoochannejhad, 1-2 Veldwijk, 2-2 Mahi (pen), 2-3 Thorsby, 3-3 Mahi (pen) |
| 2 | 18/08/2017 | Roda JC Kerkrade | Vitesse | 1-3 | 12.004 | Kamphuis | 0-1 Matavz, 1-1 Pasveer (e.d.), 1-2 Bruns, 1-3 Kashia |
| 2 | 19/08/2017 | FC Twente | VVV-Venlo | 1-2 | 23.000 | Mulder | 0-1 Van Crooy, 0-2 Promes, 1-2 Boere |
| 2 | 19/08/2017 | sc Heerenveen | Heracles Almelo | 1-1 | 18.300 | Vd Graaf | 0-1 Pröpper, 1-1 Mihajlovic |
| 2 | 20/08/2017 | Ajax | FC Groningen | 3-1 | 45.000 | Higler | 1-0 Huntelaar, 2-0 Ziyech, 1-2 Idrissi, 3-1 Schöne |
| 2 | 19/08/2017 | AZ | ADO Den Haag | 2-0 | 12.749 | Makkelie | 1-0 Weghorst (pen), 2-0 Til; R: Kanon (ADO) |
| 2 | 20/08/2017 | Excelsior | Feyenoord | 0-1 | 4.400 | Kuipers | 0-1 Boëtius |
| 2 | 20/08/2017 | FC Utrecht | Willem II | 2-0 | 16.093 | Gözübüyük | 1-0 Labyad, 2-0 Dessers |
| 2 | 20/08/2017 | Sparta Rotterdam | PEC Zwolle | 1-1 | 10.012 | Lindhout | 0-1 Mokhtar, 1-1 Mühren |
| 2 | 20/08/2017 | NAC Breda | PSV | 1-4 | 18.788 | Van Boekel | 0-1 Bergwijn, 1-1 Ambrose (pen), 1-2 Van Ginkel, 1-3 Lozano, 1-4 Hendrix |
| 3 | 25/08/2017 | NAC Breda | Sparta Rotterdam | 2-2 | 17.912 | Higler | 1-0 Marí, 2-0 Vloet, 2-1 en 2-2 Ache |
| 3 | 26/08/2017 | Vitesse | AZ | 1-2 | 14.500 | Blom | 0-1 Weghorst, 1-1 Matavz, 1-2 Weghorst |
| 3 | 26/08/2017 | ADO Den Haag | sc Heerenveen | 1-2 | 7.902 | Kamphuis | 0-1 en 0-2 Thorsby, 1-2 Johnsen |
| 3 | 26/08/2017 | PEC Zwolle | FC Twente | 2-0 | 12.800 | Janssen | 1-0 Mokhtar, 2-0 Van Polen (pen) |
| 3 | 26/08/2017 | Heracles Almelo | Excelsior | 2-2 | 10.067 | Vd Kerkhof | 1-0 Kuwas, 1-1 Bruins, 2-1 Gladon, 2-2 Caenepeel; R: Hadouir (Exc) |
| 3 | 27/08/2017 | Feyenoord | Willem II | 5-0 | 47.500 | Nijhuis | 1-0 Toornstra, 2-0 Berghuis, 3-0 Toornstra, 4-0 Vilhena, 5-0 Boëtius (pen) |
| 3 | 27/08/2017 | VVV-Venlo | Ajax | 0-2 | 8.000 | Kuipers | 0-1 Van de Beek, 0-2 Neres |
| 3 | 27/08/2017 | PSV | Roda JC Kerkrade | 2-0 | 32.200 | Makkelie | 1-0 Locadia, 2-0 Lozano |
| 3 | 27/08/2017 | FC Groningen | FC Utrecht | 2-1 | 16.032 | Manschot | 1-0 Warmerdam, 2-0 Drost, 2-1 Bahebeck |
| 4 | 09/09/2017 | Willem II | ADO Den Haag | 1-2 | 11.123 | Higler | 0-1 El Khayati (pen), 1-1 Sol, 1-2 El Khayati |
| 4 | 09/09/2017 | Heracles Almelo | Feyenoord | 2-4 | 11.331 | Makkelie | 0-1 en 0-2 Berghuis, 0-3 Boëtius, 1-3 en 2-3 (pen) Niemeijer, 2-4 Larsson |
| 4 | 09/09/2017 | Ajax | PEC Zwolle | 3-0 | 45.000 | Gözübüyük | 1-0 Huntelaar, 2-0 Ziyech, 3-0 Huntelaar |
| 4 | 09/09/2017 | Excelsior | Vitesse | 0-3 | 4.100 | Nijhuis | 0-1 Castaignos, 0-2 Matavz (pen), 0-3 Linssen |
| 4 | 10/09/2017 | sc Heerenveen | PSV | 2-0 | 22.345 | Blom | 1-0 Zeneli, 2-0 Ghoochannejhad; R: Lozano (PSV) |
| 4 | 10/09/2017 | FC Utrecht | Roda JC Kerkrade | 2-0 | 19.042 | S. Mulder | 1-0 Van de Streek, 2-0 Labyad |
| 4 | 10/09/2017 | Sparta Rotterdam | FC Twente | 1-0 | 10.034 | Bax | 1-0 Goodwin; R: Thesker |
| 4 | 10/09/2017 | AZ | NAC Breda | 2-1 | 12.511 | Janssen | 1-0 Helmer, 2-0 Til, 2-1 Korte |
| 4 | 10/09/2017 | FC Groningen | VVV-Venlo | 1-1 | 15.832 | Lindhout | 1-0 Mahi, 1-1 Nwakali |
| 5 | 15/09/2017 | Sparta Rotterdam | AZ | 0-2 | 10.210 | S. Mulder | 0-1 en 0-2 Weghorst |
| 5 | 16/09/2017 | Excelsior | sc Heerenveen | 1-2 | 4.034 | Lindhout | 1-0 Koolwijk, 1-1 Zeneli, 1-2 Rojas |
| 5 | 16/09/2017 | Roda JC Kerkrade | Willem II | 1-3 | 11.668 | Van Boekel | 0-1 Velikonja, 0-2 Sol, 0-3 Velikonja, 1-3 Rosheuvel |
| 5 | 16/09/2017 | NAC Breda | FC Groningen | 2-1 | 18.563 | Makkelie | 1-0 en 2-0 Vloet, 2-1 Mahi |
| 5 | 16/09/2017 | PEC Zwolle | Heracles Almelo | 2-1 | 12.500 | Manschot | 1-0 Mokhtar, 1-1 Monteiro, 2-1 Mokhtar |
| 5 | 17/09/2017 | Vitesse | VVV-Venlo | 1-1 | 15.000 | Higler | 1-0 Matavz, 1-1 Leemans |
| 5 | 17/09/2017 | ADO Den Haag | Ajax | 1-1 | 12.016 | Nijhuis | 0-1 Veltman, 1-1 Johnsen |
| 5 | 17/09/2017 | FC Twente | FC Utrecht | 4-0 | 24.000 | Kamphuis | 1-0 Boere, 2-0 Lam, 3-0 Slagveer, 4-0 Assaïdi |
| 5 | 17/09/2017 | PSV | Feyenoord | 1-0 | 35.000 | Kuipers | 1-0 Pereiro; R: Berghuis |
| 6 | 23/09/2017 | Willem II | sc Heerenveen | 1-2 | 10.740 | Janssen | 1-0 Lieftink, 1-1 Schaars, 1-2 Kobayashi |
| 6 | 24/09/2017 | Ajax | Vitesse | 1-2 | 50.000 | Van Boekel | 0-1 Kashia, 0-2 Rashica, 1-2 Viergever |
| 6 | 23/09/2017 | Feyenoord | NAC Breda | 0-2 | 47.500 | Kamphuis | 0-1 Korte, 0-2 Enevoldsen |
| 6 | 23/09/2017 | ADO Den Haag | Sparta Rotterdam | 1-0 | 9.641 | Manschot | 1-0 El Khayati |
| 6 | 23/09/2017 | Heracles Almelo | Roda JC Kerkrade | 2-1 | 9.943 | Kuipers | 0-1 Paulissen, 1-1 Pröpper, 2-1 Vermeij |
| 6 | 24/09/2017 | FC Utrecht | PSV | 1-7 | 22.006 | Gözübüyük | 0-1 Locadia, 1-1 Labyad (pen), 1-2 Lozano, 1-3 en 1-4 Locadia, 1-5 Van Ginkel (pen), 1-6 Locadia, 1-7 Bergwijn; R: TRoupee (Utr) |
| 6 | 24/09/2017 | VVV-Venlo | PEC Zwolle | 1-1 | 6.621 | Nijhuis | 0-1 Ehizibue, 1-1 Leemans |
| 6 | 24/09/2017 | FC Groningen | FC Twente | 1-0 | 20.110 | Vd Kerkhof | 1-0 Idrissi |
| 6 | 24/09/2017 | AZ | Excelsior | 0-2 | 12.527 | Blom | 0-1 en 0-2 Bruins (pen) |
| 7 | 29/09/2017 | FC Twente | Heracles Almelo | 2-1 | 27.100 | Higler | 1-0 Jensen, 1-1 Gladon, 2-1 Holla |
| 7 | 30/09/2017 | NAC Breda | ADO Den Haag | 0-1 | 18.523 | S. Mulder | 0-1 Beugelsdijk |
| 7 | 30/09/2017 | PEC Zwolle | FC Groningen | 3-2 | 13.160 | Van Boekel | 0-1 Doan, 1-1 Nijland, 1-2 Van Weert, 2-2 Thomas, 3-2 Mokhtar; R: Van Weert (Gro) |
| 7 | 30/09/2017 | Excelsior | VVV-Venlo | 0-2 | 4.400 | Bax | 0-1 Leemans, 0-2 Seuntjens |
| 7 | 30/09/2017 | PSV | Willem II | 4-0 | 32.500 | Manschot | 1-0 Lozano, 2-0 Pereiro, 3-0 Lozano, 4-0 Van Ginkel (pen) |
| 7 | 01/10/2017 | Sparta Rotterdam | Roda JC Kerkrade | 1-2 | 9.834 | Makkelie | 0-1 Ndenge, 0-2 Schahin, 1-2 Mühren |
| 7 | 01/10/2017 | AZ | Feyenoord | 0-4 | 14.644 | Nijhuis | 0-1 Berghuis, 0-2 Larsson, 0-3 Berghuis, 0-4 Vilhena |
| 7 | 01/10/2017 | sc Heerenveen | Ajax | 0-4 | 25.600 | Gözübüyük | 0-1 en 0-2 Neres, 0-3 Schöne (pen), 0-4 Wöber |
| 7 | 01/10/2017 | Vitesse | FC Utrecht | 1-1 | 15.432 | Kuipers | 0-1 Dessers, 1-1 Mount |
| 8 | 14/10/2017 | Roda JC Kerkrade | NAC Breda | 1-0 | 12.230 | Vd Graaf | 1-0 Auassar |
| 8 | 14/10/2017 | Ajax | Sparta Rotterdam | 4-0 | 45.000 | Blom | 1-0 Sanusi (e.d.), 2-0n Floranus (e.d.), 3-0 Neres, 4-0 Younes |
| 8 | 14/10/2017 | Feyenoord | PEC Zwolle | 0-0 | 47.500 | Higler | |
| 8 | 14/10/2017 | FC Utrecht | sc Heerenveen | 3-1 | 17.771 | Mulder | 0-1 Schaars, 1-1 Ayoub, 2-1 en 3-1 Bahebeck |
| 8 | 15/10/2017 | Heracles Almelo | Vitesse | 1-1 | 11.164 | Lindhout | 1-0 Peterson, 1-1 Linssen |
| 8 | 15/10/2017 | Willem II | FC Twente | 3-1 | 12.019 | Martens | 0-1 Assaidi (pen), 1-1 Sol, 2-1 Azzaoui, 3-1 Sol |
| 8 | 15/10/2017 | VVV-Venlo | PSV | 2-5 | 8.000 | Makkelie | 0-1 Locadia, 1-1 Leemans (pen), 2-1 Hunte, 2-2 Pereiro, 2-3 Schwaab, 2-4 Junior, 2-5 Pereiro; R: Promes (VVV) |
| 8 | 15/10/2017 | FC Groningen | AZ | 1-1 | 17.680 | Kuipers | 0-1 Jahanbakshsh, 1-1 Mahi |
| 8 | 15/10/2017 | ADO Den Haag | Excelsior | 1-2 | 10.805 | Gözübüyük | 0-1 Caenepeel, 1-1 Becker, 1-2 Faik R: Duplan (ADO) |
| 9 | 20/10/2017 | FC Groningen | Willem II | 0-1 | 16.394 | Lindhout | 0-1 Sol; R: Hrustic (Gro) |
| 9 | 21/10/2017 | NAC Breda | PEC Zwolle | 0-2 | 18.423 | Vd Kerkhof | 0-1 Van Polen (pen), 0-2 Saymak |
| 9 | 21/10/2017 | Excelsior | Sparta Rotterdam | 1-1 | 4.400 | Mulder | 1-0 Massop, 1-1 Goodwin |
| 9 | 21/10/2017 | VVV-Venlo | ADO Den Haag | 0-2 | 6.532 | Manschot | 0-1 Falkenburg, 0-2 Johnsen |
| 9 | 21/10/2017 | FC Twente | Roda JC Kerkrade | 3-0 | 23.600 | Gözübüyük | 1-0 (pen) en 2-0 Assaidi, 3-0 Bijen |
| 9 | 22/10/2017 | PSV | Heracles Almelo | 3-0 | 32.800 | Janssen | 1-0 Lozano, 2-0 en 3-0 (pen) Van Ginkel R: Pröpper (Her) |
| 9 | 22/10/2017 | Feyenoord | Ajax | 1-4 | 47.500 | Makkelie | 0-1 Huntelaar, 1-1 Toornstra, 1-2 Dolberg, 1-3 S. de Jong, 1-4 Dolberg |
| 9 | 22/10/2017 | AZ | FC Utrecht | 3-0 | 14.056 | Kamphuis | 1-0 Koopmeiners, 2-0 Jahanbakhsh, 3-0 Van Overeem |
| 9 | 22/10/2017 | sc Heerenveen | Vitesse | 0-4 | 21.034 | Bax | 0-1 Rashica, 0-2 Linssen, 0-3 Foor, 0-4 Matavz |
| 10 | 27/10/2017 | FC Twente | Excelsior | 1-3 | 23.200 | Lindhout | 1-0 Boere, 1-1 Faik, 1-2 Massop, 1-3 Karami |
| 10 | 28/10/2017 | Heracles Almelo | VVV-Venlo | 3-0 | 10.364 | Pérez | 1-0 Kuwas, 2-0 en 3-0 Peterson |
| 10 | 28/10/2017 | Roda JC Kerkrade | Feyenoord | 1-1 | 13.491 | Blom | 0-1 Berghuis, 1-1 Schahin |
| 10 | 28/10/2017 | Willem II | Ajax | 1-3 | 13.907 | Higler | 1-0 Velikonja (pen), 1-1 Schöne, 1-2 S. de Jong, 1-3 Neres |
| 10 | 28/10/2017 | PEC Zwolle | ADO Den Haag | 2-0 | 13.020 | Vd Graaf | 1-0 Parzyszek, 2-0 Namli |
| 10 | 29/10/2017 | Vitesse | PSV | 2-4 | 18.232 | Gözübüyük | 0-1 Lozano, 1-1 Locadia (e.d.), 1-2, 1-3 en 1-4 Locadia, 2-4 Mount |
| 10 | 29/10/2017 | FC Utrecht | NAC Breda | 2-2 | 20.123 | Bax | 1-0 Janssen, 1-1 El Allouchi, 1-2 Korte, 2-2 Venema |
| 10 | 29/10/2017 | Sparta Rotterdam | FC Groningen | 2-1 | 10.010 | Nijhuis | 1-0 Mühren, 1-1 Reis, 2-1 Brogno (pen) R: Veenhoven (Spa) |
| 10 | 29/10/2017 | sc Heerenveen | AZ | 1-2 | 19.136 | Janssen | 1-0 Vlap, 1-1 en 1-2 Til |
| 11 | 03/11/2017 | Sparta Rotterdam | sc Heerenveen | 0-0 | 10.231 | Manschot | |
| 11 | 04/11/2017 | AZ | Willem II | 3-2 | 13.500 | Blom | 0-1 Rienstra, 1-1 Jahanbakhsh (pen), 2-1 Til, 3-1 Weghorst, 3-2 Azzaoui; R: Weghorst (AZ) |
| 11 | 04/11/2017 | Excelsior | Roda JC Kerkrade | 1-0 | 4.086 | Dieperink | 1-0 Bruins; R: Rosheuvel (Rod) |
| 11 | 04/11/2017 | Heracles Almelo | FC Groningen | 2-1 | 10.411 | Vd Kerkhof | 1-0 Niemeijer, 1-1 Veldwijk (p), 2-1 Hardeveld (p) |
| 11 | 04/11/2017 | VVV-Venlo | NAC Breda | 0-0 | 6.521 | Kamphuis | |
| 11 | 05/11/2017 | ADO Den Haag | Feyenoord | 2-2 | 13.870 | Nijhuis | 0-1 Jørgensen, 1-1 Meijers, 2-1 Kanon, 2-2 El Ahmadi |
| 11 | 05/11/2017 | Ajax | FC Utrecht | 1-2 | 50.000 | Kuipers | 0-1 Labyad, 1-1 Viergever, 1-2 Labyad |
| 11 | 05/11/2017 | Vitesse | PEC Zwolle | 0-0 | 18.349 | Makkelie | |
| 11 | 05/11/2017 | PSV | FC Twente | 4-3 | 33.040 | Higler | 1-0 Locadia, 1-1 Thesker, 2-1 Van Ginkel, 2-2 Lam, 3-2 L. de Jong, 3-3 Jensen, 4-3 Thesker (e.d.) |
| 12 | 18/11/2017 | FC Twente | sc Heerenveen | 0-4 | 24.000 | Kamphuis | 0-1 Høegh, 0-2 Vlap, 0-3 Ødegaard, 0-4 Veerman |
| 12 | 18/11/2017 | Feyenoord | VVV-Venlo | 1-1 | 47.500 | Higler | 1-0 Jørgensen, 1-1 Van Bruggen |
| 12 | 18/11/2017 | NAC Breda | Ajax | 0-8 | 18.969 | Makkelie | 0-1 De Ligt, 0-2 en 0-3 Van de Beek, 0-4 Neres, 0-5 De Ligt, 0-6 Schöne (pen), 0-7 Huntelaar, 0-8 Van de Beek |
| 12 | 18/11/2017 | Willem II | Sparta Rotterdam | 2-2 | 11.511 | Vd Graaf | 0-1 en 0-2 Duarte, 1-2 Haye, 2-2 Ogbeche |
| 12 | 19/11/2017 | ADO Den Haag | Heracles Almelo | 4-1 | 11.175 | Blom | 0-1 Niemeijer, 1-1 Lorenzen, 2-1 El Khayati, 3-1 Johnsen, 4-1 Hooi |
| 12 | 19/11/2017 | PEC Zwolle | PSV | 0-1 | 13.250 | Kuipers | 0-1 Isimat-Mirin |
| 12 | 19/11/2017 | FC Utrecht | Excelsior | 3-1 | 18.336 | Nijhuis | 1-0 Dessers, 2-0 Ayoub, 3-0 Janssen, 3-1 El Azzouzi |
| 12 | 19/11/2017 | FC Groningen | Vitesse | 4-2 | 17.263 | Manschot | 0-1 Larsen (e.d.), 1-1 Dabo (e.d.), 1-2 Matavz (p), 2-2 Idrissi, 3-2 Mahi, 4-2 V. Weert; R: Reis (Gro) |
| 12 | 19/11/2017 | Roda JC Kerkrade | AZ | 0-1 | 12.411 | Lindhout | 0-1 Seuntjens |
| 13 | 24/11/2017 | AZ | FC Twente | 2-0 | 14.601 | Vd Kerkhof | 1-0 Jahanbakhsh (pen), 2-0 Van Overeem |
| 13 | 25/11/2017 | VVV-Venlo | Willem II | 3-3 | 6.782 | Mulder | 1-0 Van Crooy, 2-0 Van Bruggen, 2-1 Ogbeche, 3-1 Leemans (pen), 3-2 en 3-3 Ogbeche |
| 13 | 25/11/2017 | Heracles Almelo | NAC Breda | 2-1 | 10.626 | Van Boekel | 0-1 Angelino, 1-1 Niemeijer, 2-1 Gladon |
| 13 | 25/11/2017 | FC Groningen | Feyenoord | 0-2 | 20.294 | Makkelie | 0-1 Vilhena, 0-2 Jørgensen |
| 13 | 25/11/2017 | sc Heerenveen | PEC Zwolle | 1-2 | 20.832 | Gözübüyük | 1-0 Vlap, 1-1 Freire, 1-2 Saymak |
| 13 | 26/11/2017 | Ajax | Roda JC Kerkrade | 5-1 | 40.000 | Nijhuis | 0-1 Kum, 1-1 Kluivert, 2-1 Dolberg, 3-1 Kluivert, 4-1 Van de Beek, 5-1 Kluivert |
| 13 | 26/11/2017 | Excelsior | PSV | 1-2 | 4.400 | Kamphuis | 0-1 Mattheij (e.d.), 0-2 Lozano, 1-2 Koolwijk |
| 13 | 26/11/2017 | Sparta Rotterdam | FC Utrecht | 1-3 | 10.432 | Lindhout | 0-1 Labyad, 1-1 Proschwitz, 1-2 Labyad, 1-3 Kerk |
| 13 | 26/11/2017 | Vitesse | ADO Den Haag | 2-0 | 14.754 | Janssen | 1-0 Miazga, 2-0 Linssen; R: Ebuehi (ADO) |
| 14 | 01/12/2017 | PEC Zwolle | FC Utrecht | 1-1 | 13.250 | Janssen | 0-1 Van de Streek, 1-1 Saymak |
| 14 | 02/12/2017 | ADO Den Haag | FC Groningen | 0-3 | 10.416 | Gözübüyük | 0-1 Doan, 0-2 Idrissi, 0-3 Bacuna |
| 14 | 02/12/2017 | FC Twente | Ajax | 3-3 | 27.500 | Higler | 0-1 en 0-2 Schöne, 1-2 en 2-2 Thesker, 2-3 Kluivert, 3-3 Boere |
| 14 | 02/12/2017 | Feyenoord | Vitesse | 1-0 | 47.500 | Van Boekel | 1-0 Jørgensen |
| 14 | 02/12/2017 | Willem II | Heracles Almelo | 3-1 | 11.230 | Makkelie | 1-0 Sol, 2-0 en 3-0 Ogbeche, 3-1 Jakubiak |
| 14 | 03/12/2017 | VVV-Venlo | AZ | 0-2 | 6.353 | Nijhuis | 0-1 Seuntjens (e.d.), 0-2 Hatzidiakos |
| 14 | 03/12/2017 | PSV | Sparta Rotterdam | 1-0 | 33.000 | Mulder | 1-0 De Jong |
| 14 | 03/12/2017 | Roda JC Kerkrade | sc Heerenveen | 2-1 | 10.482 | Bax | 0-1 Veerman, 1-1 Schahin, 2-1 Milts |
| 14 | 03/12/2017 | NAC Breda | Excelsior | 3-1 | 18.340 | Blom | 1-0 en 2-0 Ambrose (pen), 2-1 Van Duinen, 3-1 Fernandes |
| 15 | 08/12/2017 | Willem II | NAC Breda | 1-1 | 14.400 | Nijhuis | 1-0 Ogbeche, 1-1 Ambrose |
| 15 | 09/12/2017 | sc Heerenveen | VVV-Venlo | 2-2 | 17.500 | Dieperink | 0-1 Thy, 1-1 Dumfries, 2-1 Veerman, 2-2 Seuntjens |
| 15 | 09/12/2017 | AZ | Heracles Almelo | 5-0 | 13.863 | Vd Graaf | 1-0 Castro (e.d.), 2-0 Til, 3-0 Jahanbakhsh, 4-0 Weghorst, 5-0 Svensson |
| 15 | 09/12/2017 | Excelsior | PEC Zwolle | 1-2 | 4.069 | Manschot | 1-0 Van Duinen (pen), 1-1 Saymak, 1-2 Namli R: Elbers (Exc) |
| 15 | 09/12/2017 | FC Twente | ADO Den Haag | 2-3 | 23.000 | Lindhout | 1-0 Holla, 1-1 El Khayati, 1-2 Johnsen, 2-2 Holla, 2-3 El Khayati |
| 15 | 10/12/2017 | Roda JC Kerkrade | FC Groningen | 2-2 | 10.000 | Van Boekel | 1-0 en 2-0 Gustafson, 2-1 en 2-2 (p) Van Weert R: Auassar (Rod) |
| 15 | 10/12/2017 | Ajax | PSV | 3-0 | 52.379 | Blom | 1-0 Neres, 2-0 Schöne, 3-0 Van de Beek |
| 16 | 12/12/2017 | NAC Breda | FC Twente | 1-2 | 17.589 | Mulder | 0-1 Assaidi, 1-1 Bijen (e.d.), 1-2 Assaidi R: Bertrams (NAC) |
| 16 | 12/12/2017 | PEC Zwolle | AZ | 1-1 | 12.875 | Higler | 1-0 Ondaan, 1-1 Jahanbakhsh |
| 16 | 13/12/2017 | Vitesse | Willem II | 2-2 | 13.961 | Gözübüyük | 0-1 Ogbeche, 1-1 Matavz, 1-2 Rienstra, 2-2 Linssen |
| 16 | 13/12/2017 | FC Groningen | PSV | 3-3 | 20.000 | Nijhuis | 0-1 Van Ginkel, 0-2 Ramselaar, 1-2 Van Nieff, 1-3 Van Ginkel (pen), 2-3 Veldwijk (pen), 3-3 te Wierik |
| 16 | 13/12/2017 | VVV-Venlo | FC Utrecht | 0-1 | 5.778 | Manschot | 0-1 Kerk |
| 16 | 13/12/2017 | Feyenoord | sc Heerenveen | 1-1 | 40.000 | Blom | 1-0 Berghuis, 1-1 Veerman |
| 16 | 13/12/2017 | ADO Den Haag | Roda JC Kerkrade | 3-2 | 9.151 | Wiedemeijer | 0-1 Schahin, 1-1 Immers, 1-2 Gastafson (pen), 2-2 Immers, 3-2 Falkenburg R: Dijkhuizen (Rod) |
| 16 | 14/12/2017 | Heracles Almelo | Sparta Rotterdam | 3-2 | 9.203 | Kamphuis | 1-0 Wuytens, 1-1 Proschwitz, 2-1 Niemeijer, 2-2 Proschwitz, 3-2 Vermeij |
| 16 | 14/12/2017 | Ajax | Excelsior | 3-1 | 40.000 | Janssen | 1-0 S. de Jong, 1-1 Van Duinen, 2-1 Dolberg (p), 3-1 Ziyech |
| 17 | 16/12/2017 | sc Heerenveen | NAC Breda | 1-0 | 19.361 | Lindhout | 1-0 Van Amersfoort |
| 17 | 16/12/2017 | Willem II | PEC Zwolle | 2-3 | 12.900 | Wiedemeijer | 1-0 Sol, 2-0 Rienstra, 2-1 Bakker (pen), 2-2 en 2-3 Saymak |
| 17 | 16/12/2017 | PSV | ADO Den Haag | 3-0 | 32.700 | Kuipers | 1-0 en 2-0 De Jong, 3-0 Van Ginkel (pen) R: Meissner (ADO) |
| 17 | 16/12/2017 | FC Twente | Vitesse | 1-1 | 23.600 | Manschot | 1-0 Jensen, 1-1 Mount |
| 17 | 16/12/2017 | Roda JC Kerkrade | VVV-Venlo | 0-1 | 13.189 | Higler | 0-1 Leemans; R: Auassar (Rod) |
| 17 | 17/12/2017 | Sparta Rotterdam | Feyenoord | 0-7 | 10.400 | Gözübüyük | 0-1 Vilhena, 0-2 Vente, 0-3 St Juste, 0-4 Vilhena, 0-5 Tapia, 0-6 Berghuis, 0-7 Basacikoglu |
| 17 | 17/12/2017 | FC Utrecht | FC Groningen | 1-1 | 16.859 | Mulder | 1-0 Ayoub, 1-1 Gladon |
| 17 | 17/12/2017 | AZ | Ajax | 1-2 | 16.900 | Makkelie | 1-0 Jahanbakhsh (pen), 1-1 Huntelaar, 1-2 Schöne (pen); R: Svensson (AZ) |
| 17 | 17/12/2017 | Excelsior | Heracles Almelo | 2-0 | 3.808 | Vd Kerkhof | 1-0 Massop, 2-0 Elbers |
| 18 | 22/12/2017 | ADO Den Haag | PEC Zwolle | 4-0 | 11.107 | Blom | 1-0 Falkenburg, 2-0 Johnsen, 3-0 Falkenburg, 4-0 Johnsen |
| 18 | 24/12/2017 | VVV-Venlo | Heracles Almelo | 3-1 | 6.500 | Bax | 1-0 Thy, 1-1 Niemeijer (pen), 2-1 en 3-1 Thy |
| 18 | 23/12/2017 | AZ | sc Heerenveen | 3-1 | 15.012 | Van Boekel | 0-1 Van Amersfoort, 1-1 Dumfries (e.d.), 2-1 en 3-1 Friday; R: Thorsby (Hee) |
| 18 | 23/12/2017 | PSV | Vitesse | 2-1 | 33.000 | Higler | 0-1 Matavz, 1-1 Schwaab, 2-1 Lozano |
| 18 | 23/12/2017 | Excelsior | FC Twente | 0-0 | 4.369 | Martens | |
| 18 | 23/12/2017 | NAC Breda | FC Utrecht | 3-1 | 18.769 | Wiedemeijer | 1-0 Mari, 2-0 Ambrose, 2-1 Dessers, 3-1 Angelino; R: Strieder (Utr) |
| 18 | 24/12/2017 | Ajax | Willem II | 3-1 | 40.000 | Manschot | 0-1 Sol, 1-1 Kluivert, 2-1 Dolberg, 3-1 Neres |
| 18 | 24/12/2017 | FC Groningen | Sparta Rotterdam | 4-0 | 10.000 | Janssen | 1-0 Veldwijk, 2-0 Van Weert, 3-0 Holst (e.d.), 4-0 Doan |
| 18 | 24/12/2017 | Feyenoord | Roda JC Kerkrade | 5-1 | 40.000 | Kamphuis | 1-0 Jørgensen, 2-0 Toornstra, 2-1 Gustafson, 3-1 Jørgensen, 4-1 en 5-1 Berghuis |
| 15 | 16/01/2018 | Sparta Rotterdam | Vitesse | 0-1 | 9.258 | Makkelie | 0-1 Mount |
| 19 | 19/01/2018 | FC Utrecht | AZ | 1-1 | 18.457 | Gözübüyük | 0-1 Svensson, 1-1 Dessers |
| 19 | 20/01/2018 | Roda JC Kerkrade | FC Twente | 1-1 | 12.475 | Wiedemeijer | 0-1 Vuckic, 1-1 Schahin |
| 19 | 20/01/2018 | PEC Zwolle | NAC Breda | 1-0 | 13.120 | Kamphuis | 1-0 Mokhtar |
| 19 | 20/01/2018 | ADO Den Haag | VVV-Venlo | 1-1 | 11.008 | Higler | 1-0 Johnsen, 1-1 Opoku |
| 19 | 20/01/2018 | Vitesse | sc Heerenveen | 1-1 | 15.363 | Lindhout | 1-0 Høegh (e.d.), 1-1 Van Amersfoort |
| 19 | 21/01/2018 | Willem II | FC Groningen | 1-1 | 12.160 | Makkelie | 0-1 Doan, 1-1 Azzaoui |
| 19 | 21/01/2018 | Sparta Rotterdam | Excelsior | 2-3 | 10.224 | Van Boekel | 1-0 Massop (ed), 1-1 Messaoud, 2-1 Brogno (p), 2-2 Messaouid, 2-3 Hadouir |
| 19 | 21/01/2018 | Ajax | Feyenoord | 2-0 | 53.320 | Kuipers | 1-0 Vd Beek, 2-0 Huntelaar; R: Jørgensen (Fey) |
| 19 | 21/01/2018 | Heracles Almelo | PSV | 1-2 | 11.211 | Janssen | 0-1 Bergwijn, 1-1 Hardeveld (pen), 1-2 De Jong |
| 15 | 24/01/2018 | FC Utrecht | Feyenoord | 1-1 | 22.111 | Blom | 0-1 Larsson, 1-1 Kerk |
| 20 | 26/01/2018 | sc Heerenveen | Sparta Rotterdam | 2-1 | 18.790 | Gözübüyük | 0-1 Chabot, 1-1 Ghoochannejhad, 2-1 Dumfries |
| 20 | 27/01/2018 | FC Groningen | Heracles Almelo | 3-3 | 15.000 | Higler | 1-0 Van Weert, 1-1 Monteiro, 2-1 Drost, 3-1 Mahi, 3-2 Vermeij, 3-3 Pröpper |
| 20 | 27/01/2018 | FC Twente | PSV | 0-2 | 25.700 | Blom | 0-1 Lozano, 0-2 Arias |
| 20 | 27/01/2018 | PEC Zwolle | Vitesse | 1-2 | 13.115 | S. Mulder | 0-1 Linssen, 1-1 Namli, 1-2 Mount |
| 20 | 27/01/2018 | NAC Breda | VVV-Venlo | 0-1 | 18.443 | Manschot | 0-1 Thy |
| 20 | 28/01/2018 | FC Utrecht | Ajax | 0-0 | 21.768 | Makkelie | R: Görtler (Utr) |
| 20 | 28/01/2018 | Feyenoord | ADO Den Haag | 3-1 | 47.500 | Nijhuis | 1-0 Vilhena, 2-0 Berghuis, 2-1 Immers, 3-1 Toornstra |
| 20 | 28/01/2018 | Roda JC Kerkrade | Excelsior | 2-1 | 11.226 | Perez | 0-1 Massop, 1-1 Vancamp, 2-1 Schahin R: Bruins (Exc) |
| 20 | 28/01/2018 | Willem II | AZ | 0-2 | 11.350 | Wiedemeijer | 0-1 Seuntjens, 0-2 Jahanbakshsh |
| 21 | 02/02/2018 | Vitesse | FC Groningen | 2-0 | 14.675 | Wiedemeijer | 1-0 Miazga, 2-0 Mount |
| 21 | 03/02/2018 | sc Heerenveen | FC Twente | 1-0 | 22.290 | Manschot | 1-0 Høegh |
| 21 | 04/02/2018 | AZ | Roda JC Kerkrade | 2-2 | 15.007 | Blom | 1-0 Bangaard (e.d.), 1-1 Vancamp, 2-1 Midtsjø, 2-2 Ndenge |
| 21 | 03/02/2018 | PSV | PEC Zwolle | 4-0 | 32.800 | Gözübüyük | 1-0, 2-0 en 3-0 De Jong, 4-0 Brenet; R: Van der Hart (PEC) |
| 21 | 03/02/2018 | Heracles Almelo | ADO Den Haag | 1-1 | 10.127 | Lindhout | 0-1 Johnsen, 1-1 Niemeijer |
| 21 | 04/02/2018 | Excelsior | FC Utrecht | 2-2 | 3.997 | Kooij | 1-0 Elbers, 1-1 Van der Maarel, 1-2 Labyad, 2-2 Faik |
| 21 | 04/02/2018 | Sparta Rotterdam | Willem II | 1-0 | 10.433 | Bax | 1-0 Friday |
| 21 | 04/02/2018 | VVV-Venlo | Feyenoord | 1-0 | 8.000 | Kamphuis | 1-0 Leemans (pen) |
| 21 | 04/02/2018 | Ajax | NAC Breda | 3-1 | 45.000 | Janssen | 0-1 Ambrose, 1-1 Van de Beek, 2-1 Neres, 3-1 Ziyech; R: Meijers (NAC) |
| 22 | 07/02/2018 | FC Twente | AZ | 0-4 | 23.000 | S. Mulder | 0-1 Jahanbakshsh (pen), 0-2 en 0-3 Weghorst, 0-4 Jahanbakshsh; R: Cuevas (Twe) |
| 22 | 06/02/2018 | PEC Zwolle | sc Heerenveen | 3-2 | 12.920 | Van Boekel | 1-0 Marinus, 2-0 Namli, 2-1 Dumfries, 3-1 Saymak, 3-2 Ghoochannejhad |
| 22 | 07/02/2018 | FC Utrecht | Sparta Rotterdam | 1-0 | 15.929 | Higler | 1-0 Görtler |
| 22 | 07/02/2018 | PSV | Excelsior | 1-0 | 32.000 | Lindhout | 1-0 Lozano |
| 22 | 07/02/2018 | Willem II | VVV-Venlo | 3-0 | 11.500 | Vd Graaf | 1-0 Ogbeche, 2-0 Rienstra, 3-0 Croux |
| 22 | 07/02/2018 | NAC Breda | Heracles Almelo | 6-1 | 17.035 | Blom | 1-0 Vloet, 1-1 Vermeij, 2-1 Ambrose, 3-1 Garcia, 4-1 Te Vrede, 5-1 El Allouchi, 6-1 Sadiq; R: Breukers (Her) |
| 22 | 07/02/2018 | Roda JC Kerkrade | Ajax | 2-4 | 14.484 | Nijhuis | 1-0 Gustafson, 1-1 Van den Beek, 1-2 Ziyech, 1-3 Huntelaar, 2-3 Vancamp, 2-4 Huntelaar |
| 22 | 08/02/2018 | ADO Den Haag | Vitesse | 1-0 | 12.303 | Vd Kerkhof | 1-0 Becker |
| 22 | 08/02/2018 | Feyenoord | FC Groningen | 3-0 | 37.500 | Gözübüyük | 1-0 Toornstra, 2-0 St. Juste, 3-0 Van Persie |
| 23 | 10/02/2018 | Heracles Almelo | Willem II | 1-0 | 10.232 | Van Boekel | 1-0 Vermeij |
| 23 | 10/02/2018 | FC Utrecht | PEC Zwolle | 2-1 | 17.301 | Wiedemeijer | 1-0 Kerk, 2-0 Labyad, 2-1 Saymak |
| 23 | 10/02/2018 | Sparta Rotterdam | PSV | 1-2 | 10.591 | Nijhuis | 1-0 Dougall, 1-1 en 1-2 Bergwijn |
| 23 | 10/02/2018 | sc Heerenveen | Roda JC Kerkrade | 1-1 | 17.780 | Janssen | 0-1 Ngombo, 1-1 Zeneli |
| 23 | 10/02/2018 | AZ | VVV-Venlo | 0-0 | 13.500 | Lindhout | |
| 23 | 11/02/2018 | FC Groningen | ADO Den Haag | 0-0 | 12.500 | Manschot | |
| 23 | 11/02/2018 | Vitesse | Feyenoord | 3-1 | 16.459 | Higler | 0-1 Vilhena, 1-1 Kashia, 2-1 en 3-1 Linssen R: Basacikoglu, Malacia (Fey) |
| 23 | 11/02/2018 | Excelsior | NAC Breda | 0-0 | 3.876 | Makkelie | |
| 23 | 11/02/2018 | Ajax | FC Twente | 2-1 | 45.000 | Gözübüyük | 1-0 Kluivert, 1-1 Tighadouini, 2-1 Schöne (pen) |
| 24 | 16/02/2018 | VVV-Venlo | FC Groningen | 1-1 | 6.624 | Vd Graaf | 1-0 Van Crooy, 1-1 Doan |
| 24 | 17/02/2018 | Vitesse | Excelsior | 1-2 | 15.432 | Manschot | 1-0 Castaignos, 1-1 Faik, 1-2 Van Duinen |
| 24 | 17/02/2018 | NAC Breda | AZ | 1-3 | 18.628 | Kamphuis | 0-1 Jahanbakshsh, 0-2 Til, 0-3 Seuntjens 1-3 Sadiq |
| 24 | 17/02/2018 | PSV | sc Heerenveen | 2-2 | 33.500 | Higler | 1-0 Arias, 2-0 De Jong, 2-1 Schaars, 2-2 Ghoochannejhad; R: Lozano (PSV) |
| 24 | 17/02/2018 | ADO Den Haag | Willem II | 2-1 | 9.966 | Kooij | 0-1 Sol, 1-1 Johnsen, 2-1 El Khayati (pen) |
| 24 | 18/02/2018 | Roda JC Kerkrade | FC Utrecht | 1-4 | 10.000 | Lindhout | 0-1 Van de Streek, 0-2 Van der Maarel, 0-3 Van de Streek, 1-3 Vancamp, 1-4 Labyad |
| 24 | 18/02/2018 | Feyenoord | Heracles Almelo | 1-0 | 47.500 | Jsnssen | 1-0 Van Persie |
| 24 | 18/02/2018 | FC Twente | Sparta Rotterdam | 1-1 | 25.400 | Van Boekel | 0-1 Friday, 1-1 Vuckic |
| 24 | 18/02/2018 | PEC Zwolle | Ajax | 0-1 | 13.250 | Blom | 0-1 Huntelaar |
| 25 | 23/02/2018 | FC Groningen | NAC Breda | 1-1 | 20.000 | Higler | 1-0 Mari (e.d.), 1-1 Te Vrede |
| 25 | 24/02/2018 | AZ | Sparta Rotterdam | 2-1 | 14.884 | Gözübüyük | 0-1 Chabot, 1-1 Weghorst, 2-1 Idrissi |
| 25 | 24/02/2018 | sc Heerenveen | Excelsior | 0-1 | 18.920 | Wiedemeijer | 0-1 Van Duinen |
| 25 | 24/02/2018 | Heracles Almelo | PEC Zwolle | 2-1 | 9.031 | Nijhuis | 1-0 Peterson, 1-1 Parzyszek, 2-1 Vermeij |
| 25 | 24/02/2018 | VVV-Venlo | Vitesse | 2-2 | 6.168 | S. Mulder | 1-0 Hunte, 2-0 Thy, 2-1 Röseler (e.d.), 2-2 Mount |
| 25 | 25/02/2018 | Ajax | ADO Den Haag | 0-0 | 47.500 | Van Boekel | |
| 25 | 25/02/2018 | Feyenoord | PSV | 1-3 | 47.500 | Makkelie | 0-1 Arias, 0-2 Bergwijn, 1-2 Vilhena, 1-3 Pereiro |
| 25 | 25/02/2018 | Willem II | Roda JC Kerkrade | 1-0 | 13.277 | Manschot | 1-0 Rienstra |
| 25 | 25/02/2018 | FC Utrecht | FC Twente | 3-1 | 17.755 | Kamphuis | 0-1 Vuckic, 1-1 Klaiber, 2-1 Van de Streek, 3-1 Ayoub |
| 26 | 03/03/2018 | sc Heerenveen | Willem II | 2-0 | 10.000 | Gözübüyük | 1-0 Woudenberg, 2-0 Ghoochannejhad |
| 26 | 03/03/2018 | PSV | FC Utrecht | 3-0 | 33.800 | Blom | 1-0 Leeuwin, 2-0 De Jong, 3-0 Bergwijn |
| 26 | 03/03/2018 | Excelsior | AZ | 1-2 | 4.218 | Van Boekel | 0-1 Zwarthoed (e.d.), 0-2 Jahanbakshsh, 1-2 Massaoud |
| 26 | 02/03/2018 | Roda JC Kerkrade | Heracles Almelo | 0-3 | 10.000 | Kamphuis | 0-1 Kuwas, 0-2 Peterson, 0-2 Van Ooijen |
| 26 | 03/03/2018 | NAC Breda | Feyenoord | 2-1 | 18.963 | Nijhuis | 0-1 Toornsstra, 1-1 Ambrose, 2-1 Sadiq (pen) |
| 26 | 04/03/2018 | PEC Zwolle | VVV-Venlo | 1-1 | 12.965 | Manschot | 0-1 Van Crooy, 1-1 Saymak |
| 26 | 04/03/2018 | Sparta Rotterdam | ADO Den Haag | 2-1 | 10.482 | Wiedemeijer | 0-1 Falkenburg, 1-1 Kramer, 2-1 Mühren |
| 26 | 04/03/2018 | Vitesse | Ajax | 3-2 | 19.876 | Kuipers | 1-0 Foor, 2-0 Linssen, 2-1 Cassierra, 3-1 Linssen, 3-2 S. de Jong |
| 26 | 04/03/2018 | FC Twente | FC Groningen | 1-1 | 23.000 | Janssen | 0-1 Doan, 1-1 Boere |
| 27 | 09/03/2018 | Heracles Almelo | FC Twente | 2-1 | 12.080 | Blom | 0-1 Tighadouini, 1-1 Petersen, 2-1 Maher (e.d.) |
| 27 | 10/03/2018 | ADO Den Haag | NAC Breda | 0-2 | 13.620 | Makkelie | 0-1 El Allouchi, 0-2 Ambrose (p); R: Kanon (DH) |
| 27 | 10/03/2018 | VVV-Venlo | Excelsior | 2-3 | 6.021 | Martens | 0-1 Garcia, 1-1 Mattheij (e.d.), 1-2 Faik, 1-3 Van Duinen, 2-3 Thy |
| 27 | 10/03/2018 | Willem II | PSV | 5-0 | 13.650 | Kuipers | 1-0 Rienstra, 2-0 en 3-0 (pen) Sol, 4-0 Rienstra, 5-0 Sol; R: Luckassen (PSV) |
| 27 | 10/03/2018 | Roda JC Kerkrade | Sparta Rotterdam | 0-2 | 12.644 | Nijhuis | 0-1 Fischer, 0-2 Mühren |
| 27 | 11/03/2018 | FC Groningen | PEC Zwolle | 2-0 | 15.000 | Lindhout | 1-0 Thomas, 2-0 Hrustic |
| 27 | 11/03/2018 | FC Utrecht | Vitesse | 5-1 | 19.607 | Janssen | 1-0 Janssen, 2-0 Labyad, 2-1 Foor, 3-1 Van de Streek, 4-1 en 5-1 Ayoub |
| 27 | 11/03/2018 | Ajax | sc Heerenveen | 4-1 | 47.500 | Kamphuis | 1-0 De Ligt, 1-1 Ødegaard, 2-1 Tagliafico, 3-1 Van de Beek, 4-1 Neres |
| 27 | 11/03/2018 | Feyenoord | AZ | 2-1 | 45.000 | Higler | 1-0 Boëtius, 2-0 Jørgensen, 2-1 Weghorst |
| 28 | 16/03/2018 | Excelsior | ADO Den Haag | 1-2 | 4.400 | S. Mulder | 1-0 Massop, 1-1 en 1-2 Johnsen |
| 28 | 18/03/2018 | AZ | FC Groningen | 3-2 | 16.459 | Vd kerkhof | 1-0 Svensson, 2-0 Til, 2-1 Doan, 2-2 Van Weert, 3-2 Jahanbakhsh |
| 28 | 17/03/2018 | PSV | VVV-Venlo | 3-0 | 33.900 | Gözübüyük | 1-0 Van Ginkel, 2-0 Lozano, 3-0 Van Ginkel (p) R: Seuntjens (VVV) |
| 28 | 17/03/2018 | Vitesse | Heracles Almelo | 0-0 | 16.231 | Lindhout | |
| 28 | 17/03/2018 | sc Heerenveen | FC Utrecht | 2-2 | 18.700 | Nijhuis | 0-1 Van der Maarel, 1-1 Thorsby, 2-1 Ghoochannejhad, 2-2 Dessers |
| 28 | 17/03/2018 | FC Twente | Willem II | 2-2 | 29.000 | Wiedemeijer | 0-1 Tsimikas, 1-1 Lam, 1-2 Sol, 2-2 Bijen |
| 28 | 18/03/2018 | Sparta Rotterdam | Ajax | 2-5 | 10.606 | Higler | 0-1 Kramer, 1-1 Huntelaar, 1-2 Schöne. 1-3 Kluivert, 1-4 en 1-5 Ziyech, 2-5 Sanusi |
| 28 | 18/03/2018 | NAC Breda | Roda JC Kerkrade | 0-1 | 18.412 | Janssen | 0-1 Avdijaj |
| 28 | 18/03/2018 | PEC Zwolle | Feyenoord | 3-4 | 13.250 | Van Boekel | 0-1 en 0-2 V. Persie, 0-3 El Ahmadi, 1-3 Saymak, 1-4 Vilhena, 2-4 (pen) en 3-4 Parzyszek |
| 29 | 31/03/2018 | PEC Zwolle | Sparta Rotterdam | 2-0 | 13.250 | Nijhuis | 1-0 Mokhtar, 2-0 Parzyszek |
| 29 | 31/03/2018 | Vitesse | Roda JC Kerkrade | 0-3 | 16.591 | Higler | 0-1 Schahin, 0-2 Avdijaj, 0-3 Schahin |
| 29 | 31/03/2018 | PSV | NAC Breda | 5-1 | 34.300 | Van Boekel | 1-0 Van Ginkel (pen), 2-0 Sadiq (e.d.), 2-1 Sadiq, 3-1 De Jong, 4-1 Mets (e.d.), 5-1 Pereiro |
| 29 | 31/03/2018 | Willem II | FC Utrecht | 3-2 | 13.660 | Kamphuis | 0-1 Kerk, 0-2 Van de Streek, 1-2 Haye, 2-2 Tsimikas, 3-2 Sol; R: Heerkens (Wil) |
| 29 | 31/03/2018 | ADO Den Haag | AZ | 0-3 | 13.115 | Kuipers | 0-1 Weghorst, 0-2 Idrissi, 0-3 Jahanbakshsh |
| 29 | 01/04/2018 | Feyenoord | Excelsior | 5-0 | 45.000 | Gözübüyük | 1-0 Boëtius, 2-0 Toornstra, 3-0 Vilhena, 4-0 Berghuis, 5-0 De Wijs (e.d.) |
| 29 | 01/04/2018 | Heracles Almelo | sc Heerenveen | 1-2 | 10.086 | Janssen | 0-1 Thorsby, 0-2 Zeneli (pen), 1-2 Darri |
| 29 | 01/04/2018 | FC Groningen | Ajax | 1-2 | 22.000 | Blom | 1-0 Van Weert, 1-1 Kluivert, 1-2 Huntelaar R": Veltman (Aja) |
| 29 | 01/04/2018 | VVV-Venlo | FC Twente | 0-0 | 6.623 | Lindhout | |
| 30 | 06/04/2018 | Excelsior | Willem II | 2-1 | 4.400 | Vd Graaf | 0-1 Sol, 1-1 Bruins (pen), 2-1 Elbers R: Lachman (Wil) |
| 30 | 07/04/2018 | NAC Breda | Vitesse | 1-0 | 18.567 | Gözübüyük | 1-0 Angelino |
| 30 | 07/04/2018 | Roda JC Kerkrade | PEC Zwolle | 3-2 | 14.115 | Kuipers | 1-0 Avdijaj, 2-0 Gustafson, 2-1 Namli, 2-2 Menig, 3-2 Rosheuvel |
| 30 | 07/04/2018 | FC Twente | Feyenoord | 1-3 | 25.600 | Makkelie | 0-1 Boëtius, 1-1 Maher, 1-2 Berghuis, 1-3 Jørgensen |
| 30 | 07/04/2018 | Sparta Rotterdam | VVV-Venlo | 3-2 | 10.139 | Mulder | 1-0 Ahannach, 1-1 en 1-2 Leemans, 2-2 en 3-2 Mühren |
| 30 | 08/04/2018 | FC Utrecht | ADO Den Haag | 3-3 | 20.145 | Higler | 1-0 Van de Streek, 1-1 Johnsen, 1-2 Beugelsdijk, 2-2 Kerk, 2-3 Hooi, 3-3 Labyad |
| 30 | 08/04/2018 | sc Heerenveen | FC Groningen | 1-1 | 23.150 | Van Boekel | 1-0 Vlap, 1-1 Van Weert |
| 30 | 07/04/2018 | AZ | PSV | 2-3 | 17.002 | Blom | 0-1 en 0-2 Weghorst, 1-2 Pereiro, 2-2 Lozano, 2-3 Van Ginkel (pen); R: Vlaar (AZ) |
| 30 | 08/04/2018 | Ajax | Heracles Almelo | 1-0 | 45.000 | Nijhuis | 1-0 Neres |
| 31 | 13/04/2018 | Heracles Almelo | AZ | 0-3 | 10.724 | Kamphuis | 0-1 Til, 0-2 Idrissi, 0-3 Jahanbakhsh |
| 31 | 14/04/2018 | ADO Den Haag | FC Twente | 2-1 | 13.876 | Gözübüyük | 0-1 F. Jensen, 1-1 en 2-1 Johnsen |
| 31 | 14/04/2018 | Vitesse | Sparta Rotterdam | 7-0 | 16.345 | Blom | 1-0 Serero, 2-0 Beerens, 3-0 Fischer (e.d.), 4-0 Linssen, 5-0 Matavz, 6-0 Bruns, 7-0 Linssen; R: Kramer (Spa) |
| 31 | 14/04/2018 | VVV-Venlo | sc Heerenveen | 0-2 | 7.054 | Higler | 0-1 Ghoochannejhad, 0-2 Mihajlovic |
| 31 | 14/04/2018 | PEC Zwolle | Excelsior | 1-1 | 13.028 | Bax | 1-0 Mokhtar, 1-1 Van Duinen (pen) |
| 31 | 15/04/2018 | NAC Breda | Willem II | 1-2 | 18.481 | Janssen | 0-1 Rienstra, 1-1 Verschueren, 1-2 Rienstra |
| 31 | 15/04/2018 | Feyenoord | FC Utrecht | 3-1 | 47.500 | Nijhuis | 1-0 Jørgensen, 1-1 Dessers, 2-1 Van Persie, 3-1 Larsson |
| 31 | 15/04/2018 | FC Groningen | Roda JC Kerkrade | 2-1 | 20.000 | Lindhout | 1-0 Doan, 2-0 Drost, 2-1 Kum |
| 31 | 15/04/2018 | PSV | Ajax | 3-0 | 35.000 | Makkelie | 1-0 pereiro, 2-0 De Jong, 3-0 Bergwijn R: Tagliafico, S. de Jong (Aja) |
| 32 | 17/04/2018 | FC Twente | PEC Zwolle | 2-0 | 24.000 | Van Boekel | 1-0 Van der Lely, 2-0 Maria |
| 32 | 17/04/2018 | sc Heerenveen | ADO Den Haag | 2-0 | 18.730 | Vd Kerkhof | 1-0 en 2-0 Rojas |
| 32 | 18/04/2018 | AZ | Vitesse | 4-3 | 15.200 | Nijhuis | 1-0 Weghorst, 2-0 Jahanbakhsh, 2-1 Linssen, 2-2 Matavz, 3-2 en 4-2 Jahanbakhsh, 4-3 Mount |
| 32 | 18/04/2018 | Roda JC Kerkrade | PSV | 2-2 | 15.383 | Gözübüyük | 1-0 Vansteenkiste, 1-1 Lozano, 2-1 Gustafson, 2-2 Hendrix |
| 32 | 18/04/2018 | Sparta Rotterdam | NAC Breda | 2-1 | 10.606 | Lindhout | 1-0 Duarte, 1-1 Sadiq, 2-1 Spierings |
| 32 | 18/04/2018 | Excelsior | Heracles Almelo | 2-2 | 4.065 | Mulder | 1-0 Massaoud, 2-0 Van Duinen (pen), 2-1 en 2-2 (pen) Monteiro; R: Van Ooijen (Her) |
| 32 | 18/04/2018 | Willem II | Feyenoord | 1-5 | 13.320 | Blom | 0-1 Vente, 0-2 Amrabat, 0-3 Vilhena, 1-3 Ogbeche, 1-4 Vente, 1-5 Basacikoglu |
| 32 | 19/04/2018 | FC Utrecht | FC Groningen | 1-1 | 19.540 | Janssen | 1-0 Janssen, 1-1 Van Weert (pen) |
| 32 | 19/04/2018 | Ajax | VVV-Venlo | 4-1 | 25.000 | Kamphuis | 0-1 Seuntjes, 1-1 en 2-1 Neres, 3-1 Huntelaar, 4-1 Ziyech |
| 33 | 29/04/2018 | Feyenoord | Sparta Rotterdam | 3-1 | 45.000 | Higler | 0-1 Friday, 1-1 Berghuis, 2-1 Holst (e.d.), 3-1 Berghuis |
| 33 | 29/04/2018 | NAC Breda | sc Heerenveen | 3-0 | 18.456 | Nijhuis | 1-0 Fernandes, 2-0 Te Vrede, 3-0 Mari |
| 33 | 29/04/2018 | PEC Zwolle | Willem II | 0-1 | 13.055 | Dieperink | 0-1 Azzaoui |
| 33 | 29/04/2018 | Ajax | AZ | 3-0 | 40.000 | Gözübüyük | 1-0 Van de Beek, 2-0 Kluivert, 3-0 Neres |
| 33 | 29/04/2018 | Heracles Almelo | Excelsior | 2-2 | 11.187 | Blom | 1-0 Kuwas, 2-0 Navratil. 2-1 Van de Streek, 2-2 Van der Maarel |
| 33 | 29/04/2018 | Vitesse | FC Twente | 5-0 | 17.939 | Kamphuis | 1-0 Sereo, 2-0 Matavz, 3-0 Mount, 4-0 Linssen, 5-0 Matavz |
| 33 | 29/04/2018 | VVV-Venlo | Roda JC Kerkrade | 1-4 | 7.255 | Makkelie | 0-1 Vansteenkiste, 1-1 Hunte, 1-2 Auassar, 1-3 Schahin, 1-4 Engels |
| 33 | 29/04/2018 | FC Groningen | Excelsior | 4-0 | 15.000 | Vd Kerkhof | 1-0 Van Weert, 2-0 Memisevic, 3-0 Doan, 4-0 Van Weert |
| 33 | 29/04/2018 | ADO Den Haag | PSV | 3-3 | 14.031 | Van Boekel | 0-1 Lozano, 1-1 Johnsen, 2-1 El Khayati (pen), 2-2 Pereiro, 3-2 Johnsen, 3-3 Pereiro |
| 34 | 06/05/2018 | sc Heerenveen | Feyenoord | 2-3 | 24.640 | Makkelie | 0-1 en 0-2 Berghuis, 1-2 Bruijn, 2-2 Van der Heijden (e.d.), 2-3 Basacikoglu |
| 34 | 06/05/2018 | FC Utrecht | VVV-Venlo | 1-0 | 19.669 | Perez | 1-0 Klich |
| 34 | 06/05/2018 | Sparta Rotterdam | Heracles Almelo | 2-5 | 8.846 | Bax | 1-0 Friday, 1-1 Peterson, 1-2 Spierings, 2-2 Vermeij, 2-3 Breukers, 2-4 Gladon, 2-5 Vermeij |
| 34 | 06/05/2018 | AZ | PEC Zwolle | 6-0 | 16.532 | Lindhout | 1-0 en 2-0 Jahanbakhsh, 3-0 Midtsjø, 4-0 en 5-0 Weghorst, 6-0 Jahanbakhsh |
| 34 | 06/05/2018 | Willem II | Vitesse | 2-2 | 11.600 | S. Mulder | 1-0 Tsimikas, 1-1 Miazga, 1-2 Rienstra, 2-2 Matavz |
| 34 | 06/05/2018 | PSV | FC Groningen | 0-0 | 33.700 | Janssen | |
| 34 | 06/05/2018 | Excelsior | Ajax | 1-2 | 4.400 | Nijhuis | 1-0 De Ligt (e.d.), 1-1 Kluivert, 1-2 Dolberg (pen) |
| 34 | 06/05/2018 | Roda JC Kerkrade | ADO Den Haag | 2-3 | 13.794 | Manschot | 0-1 Johnsen, 0-2 Immers, 0-3 Johnsen, 1-3 Schahin, 2-3 Gustafson (pen) |
| 34 | 06/05/2018 | FC Twente | NAC Breda | 1-1 | 20.000 | Vd Graaf | 0-1 Koch, 1-1 George |
Play offs voor Europa League
| 1e ronde | ||||||
| 09/05/2018 | ADO Den Haag | Vitesse | 2-5 | 11.930 | Makkelie | 0-1 Matavz, 0-2 en 0-3 Mount, 0-4 Linssen, 1-4 El Khayati (pen), 1-5 Mount, 2-5 El Khayati |
| 09/05/2018 | sc Heerenveen | FC Utrecht | 4-3 | 17.225 | Janssen | 1-0 Kobayashi, 2-0 Ghoochannejhad, 3-0 Høegh, 3-1 en 3-2 Labyad, 3-3 Bulthuis (e.d.), 4-3 Dumfries; R: Ayoub (Utr) |
| 12/05/2018 | Vitesse | ADO Den Haag | 2-1 | 13.715 | Blom | 1-0 Matavz, 2-0 Mount, 2-1 El Khayati |
| 12/05/2018 | FC Utrecht | sc Heerenveen | 2-1 | 14.632 | Gözübüyük | 1-0 Strieder, 2-0 Van der Maarel, 2-1 Rojas |
| 2e ronde | ||||||
| 15/05/2018 | Vitesse | FC Utrecht | 3-2 | 14.236 | Kamphuis | 1-0 Mount, 1-1 leeuwin, 2-1 Linssen, 2-2 Labyad, 3-2 Kashia |
| 19/05/2018 | FC Utrecht | Vitesse | 1+2 | 21.353 | Nijhuis | 0-1 Leeuwin (e.d.), 0-2 Miazga, 1-2 Van der Maarel |
Play offs voor promotie/degradatie
| 1e ronde | ||||||
| 01/05/2018 | MVV Maastricht | Almere City FC | 1-3 | 4.264 | Janssen | 0-1 Mirani, 1-1 Ciranni, 1-2 en 1-3 Mirani |
| 01/05/2018 | FC Dordrecht | SC Cambuur | 1-4 | 2.412 | Bax | 0-1 Crowley, 0-2 Mathieu, 1-2 Bliek, 1-3 en 1-4 Barto |
| 05/05/2018 | Almere City FC | MVV Maastricht | 3-2 | 1.792 | Gözübüyük | 0-1 Janssen, 1-1 Van der Water, 1-2 Okita, 2-2 en 3-2 MacDonald |
| 05/05/2018 | SC Cambuur | FC Dordrecht *** | 1-4 | 7.542 | 1-0 Kallon, 1-1 Cijntje, 1-2 Arias, 1-3 (pen) en 1-4 Mahmudov | |
| 2e ronde | ||||||
| 10/05/2018 | Telstar | De Graafschap | 3-2 | 4.663 | Kamphuis | 1-0 Platje, 2-0 Navokovich, 1-1 Van Mieghem, 2-2 Serrarens, 3-2 Hamdaoui; R: Nieuwpoort (Gra), Van Huizen (Tel) |
| 10/05/2018 | FC Emmen | NEC | 4-0 | 5.378 | Vd Kerkhof | 1-0 Veldmate, 2-0 Bakker, 3-0 Loen, 4-0 Bijl |
| 10/05/2018 | FC Dordrecht | Sparta Rotterdam | 1-2 | 4.235 | S. Mulder | 0-1 Brogno, 1-1 Spierings (e.d.), 1-2 Muhren |
| 10/05/2018 | Almere City FC | Roda JC Kerkrade | 0-0 | 2.826 | Nijhuis | |
| 13/05/2018 | De Graafschap | Telstar | 4-2 | 11.083 | Van Boekel | 1-0 Nieuwpoort, 2-0 El Jebli, 2-1 Hamdaoui, 3-1 Serrarens, 3-2 Novakovich (pen), 4-2 Van Mieghem |
| 13/05/2018 | NEC | FC Emmen | 4-1 | 5.321 | Nijhuis | 1-0 en 2-0 Achahbar, 2-1 Bannink, 3-1 Sturing, 4-1 Romeny |
| 13/05/2018 | Sparta Rotterdam | FC Dordrecht | 2-2 | 10.132 | Manschot | 0-1 Mahmudov, 0-2 Cijntje, 1-2 Duarte, 2-2 Mühren |
| 13/05/2018 | Roda JC Kerkrade | Almere City FC | 1-2 | 12.489 | Lindhout | 0-1 Van der Water, 1-1 Schahin, 1-2 Hammouti |
| 3e ronde | ||||||
| 17/05/2018 | FC Emmen | Sparta Rotterdam | 0-0 | 8.301 | Lindhout | |
| 17/05/2018 | Almere City FC | De Graafschap | 1-1 | 3.430 | Blom | 1-0 Van der Water, 1-1 Serrarens (pen); R: Overtoom (Alm) |
| 20/05/2018 | Sparta Rotterdam | FC Emmen | 1-3 | 10.606 | Higler | 1-0 Sp[ierings, 1-1 Chacon, 1-2 Jansen, 1-3 Bannink R: Dougall (Spa) |
| 20/05/2018 | De Graafschap | Almere City FC | 2-1 | 12.600 | Makkelie | 0-1 Hoefdraad, 1-1 Tissoudali, 2-1 Serrarens |
FC Emmen en De Graafschap gepromoveerd, Sparta en Roda JC gedegradeerd.
Topscorers
| 1 | Alireza Jahanbakhsh | AZ | 21 |
| 2 | Bjørn Johnsen | ADO Den Haag | 19 |
| 3 | Steven Berghuis | Feyenoord | 18 |
| 4 | Wout Weghorst | AZ | 18 |
| 5 | Hirving Lozano | PSV | 17 |
| 6 | Fran Sol | Willem II | 16 |
| 7 | Bryan Linssen | Vitesse | 15 |
| 8 | Marco van Ginkel | PSV | 14 |
| 9 | Tim Matavz | Vitesse | 14 |
| 10 | David Neres | Ajax | 14 |
Het eerste kampioenschap van Feyenoord na 18 seizoenen voelt in Rotterdam als een bevrijding. Na jaren van sportieve en financiële malheur ging het al enkele jaren beter, maar de titel zat er tot deze jaargang nog niet in. Vanaf de start van het seizoen neemt de ervaren ploeg de leiding in de Eredivisie. Hoewel de positie soms wankelt en Ajax zeker na de winterstop ook nauwelijks steken laat vallen kan Feyenoord het in speelronde 33 afmaken bij Excelsior. De wedstrijd verloopt echter dramatisch voor Feyenoord en gaat met 3-0 verloren. Twee weken later komt het toch allemaal goed voor de Rotterdammers. Thuis tegen Heracles in een kolkende Kuip neemt veteraan Dirk Kuyt de ploeg met drie treffers bij de hand en bezorgd Feyenoord de 15e landstitel.
Het seizoen 2016-2017 is ook het seizoen dat Nederland Europees weer wat kleur op het gezicht krijgt. Veel voetbalvolgers hadden zich al verzoend met het idee dat een Nederlandse club nooit meer een finale zou halen, maar plotseling is daar een piepjong en ouderwets fris aanvallend Ajax dat de finale van de Europa League bereikt. Daarin is Ajax wel kansloos tegen het geslepen Manchester United van Jose Mourinho. In de competitie blijft Ajax tot de laatste dag in het spoor van Feyenoord, maar blijft het ondanks een groot puntenaantal steken op plek twee. De andere Europese plaatsen zijn voor bekerwinnaar Vitesse, PSV en FC Utrecht dat de play-offs winnend afsluit.
Het via de nacompetitie gepromoveerde Go Ahead Eagles blijkt te licht voor de Eredivisie en degradeert na één seizoen weer. De strijd voor het ontlopen van de nacompetitieplaatsen is spannend tot de laatste speeldag. Uiteindelijk moeten Roda JC en NEC het verplichte toetje ondergaan, waarbij Roda JC het vege lijf redt, terwijl NEC het onderspit delft tegen NAC Breda.
Uitslagenmatrix
| ADO | AJA | AZ | EXC | FEY | GOA | GRO | HEE | HER | NEC | PEC | PSV | ROD | SPA | TWE | UTR | VIT | WIL | |
| ADO Den Haag | * | 0-2 | 0-1 | 4-1 | 0-1 | 3-0 | 4-3 | 0-3 | 1-1 | 1-0 | 1-2 | 1-1 | 4-1 | 1-0 | 1-1 | 0-2 | 0-2 | 1-0 |
| Ajax | 3-0 | * | 4-1 | 1-0 | 2-1 | 4-0 | 2-0 | 5-1 | 4-1 | 5-0 | 5-1 | 1-1 | 2-2 | 2-0 | 3-0 | 3-2 | 1-0 | 1-2 |
| AZ | 4-0 | 2-2 | * | 1-1 | 0-4 | 2-2 | 0-0 | 2-2 | 5-1 | 2-0 | 1-1 | 2-4 | 1-1 | 1-1 | 2-1 | 2-3 | 2-2 | 2-0 |
| Excelsior | 1-2 | 1-1 | 3-3 | * | 3-0 | 1-1 | 2-0 | 4-1 | 3-1 | 2-2 | 0-2 | 1-3 | 0-1 | 3-2 | 1-1 | 1-3 | 1-0 | 0-2 |
| Feyenoord | 3-1 | 1-1 | 5-2 | 4-1 | * | 8-0 | 2-0 | 2-2 | 3-1 | 4-0 | 3-0 | 2-1 | 5-0 | 6-1 | 2-0 | 2-0 | 3-1 | 1-0 |
| Go Ahead Eagles | 3-1 | 0-3 | 1-3 | 3-0 | 1-0 | * | 2-3 | 1-3 | 1-4 | 2-2 | 1-3 | 1-3 | 2-0 | 1-3 | 0-2 | 0-1 | 1-3 | 0-1 |
| FC Groningen | 2-1 | 1-1 | 2-0 | 1-1 | 0-5 | 1-1 | * | 0-3 | 0-0 | 2-0 | 5-1 | 1-1 | 2-0 | 1-1 | 3-4 | 2-3 | 1-1 | 1-1 |
| sc Heerenveen | 2-0 | 0-1 | 1-2 | 2-1 | 1-2 | 2-2 | 0-0 | * | 3-1 | 0-2 | 1-0 | 1-1 | 3-0 | 3-0 | 3-1 | 2-2 | 1-1 | 1-0 |
| Heracles Almelo | 4-0 | 0-2 | 1-2 | 4-0 | 0-1 | 2-1 | 1-4 | 4-1 | * | 2-0 | 3-0 | 1-2 | 2-2 | 2-2 | 1-1 | 2-1 | 0-1 | 3-1 |
| NEC | 3-0 | 1-5 | 2-1 | 0-1 | 1-2 | 1-2 | 1-1 | 2-1 | 3-1 | * | 1-1 | 0-4 | 2-0 | 0-1 | 3-2 | 0-3 | 1-1 | 0-0 |
| PEC Zwolle | 2-1 | 1-3 | 0-2 | 1-1 | 3-1 | 3-1 | 0-4 | 2-1 | 1-2 | 2-0 | * | 0-4 | 0-0 | 0-3 | 1-2 | 1-1 | 3-1 | 0-0 |
| PSV | 3-1 | 1-0 | 1-0 | 2-0 | 0-1 | 1-0 | 0-0 | 4-3 | 1-1 | 3-1 | 4-1 | * | 4-0 | 1-0 | 1-1 | 3-0 | 1-0 | 5-0 |
| Roda JC | 1-1 | 0-2 | 1-1 | 4-0 | 0-2 | 1-0 | 3-1 | 0-3 | 1-1 | 0-1 | 2-1 | 0-0 | * | 3-1 | 0-3 | 0-0 | 0-1 | 1-0 |
| Sparta R. | 0-1 | 1-3 | 1-1 | 2-3 | 1-0 | 1-0 | 2-2 | 3-1 | 3-1 | 2-0 | 2-3 | 0-2 | 2-2 | * | 1-0 | 1-2 | 0-1 | 2-2 |
| FC Twente | 4-1 | 1-0 | 1-2 | 1-2 | 0-2 | 1-2 | 3-5 | 1-0 | 1-0 | 3-0 | 2-2 | 2-0 | 0-0 | 3-1 | * | 1-1 | 2-1 | 2-1 |
| FC Utrecht | 1-1 | 0-1 | 1-2 | 2-1 | 3-3 | 3-0 | 1-5 | 1-0 | 2-0 | 1-1 | 3-1 | 1-2 | 1-0 | 2-0 | 3-0 | * | 1-0 | 2-0 |
| Vitesse | 1-2 | 0-1 | 2-1 | 2-2 | 0-2 | 2-0 | 2-1 | 4-2 | 1-2 | 2-1 | 3-1 | 0-2 | 3-0 | 5-0 | 3-1 | 1-1 | * | 0-2 |
| Willem II | 1-2 | 1-3 | 1-1 | 1-1 | 0-2 | 2-0 | 2-1 | 2-1 | 1-3 | 0-1 | 2-0 | 0-0 | 0-0 | 3-2 | 0-0 | 0-1 | 1-4 | * |
Eindstand
| 1 | Feyenoord * | 34 | 26 | 4 | 4 | 82 | 86 | 25 | 61 | 47.500 |
| 2 | Ajax ** | 34 | 25 | 6 | 3 | 81 | 79 | 23 | 56 | 46.543 |
| 3 | PSV *** | 34 | 22 | 10 | 2 | 76 | 68 | 23 | 45 | 33.176 |
| 4 | FC Utrecht + *** | 34 | 18 | 8 | 8 | 62 | 54 | 38 | 16 | 18.276 |
| 5 | Vitesse *** | 34 | 15 | 6 | 13 | 51 | 51 | 40 | 11 | 15.812 |
| 6 | AZ + | 34 | 12 | 13 | 9 | 49 | 56 | 52 | 4 | 14.702 |
| 7 | FC Twente | 34 | 12 | 9 | 13 | 45 | 48 | 50 | -2 | 25.112 |
| 8 | FC Groningen + | 34 | 10 | 13 | 11 | 43 | 55 | 51 | 4 | 16.908 |
| 9 | sc Heerenveen + | 34 | 12 | 7 | 15 | 43 | 54 | 53 | 1 | 21.824 |
| 10 | Heracles Almelo | 34 | 12 | 7 | 15 | 43 | 53 | 55 | -2 | 11.022 |
| 11 | ADO Den Haag | 34 | 11 | 5 | 18 | 38 | 37 | 59 | -12 | 11.343 |
| 12 | Excelsior | 34 | 9 | 10 | 15 | 37 | 43 | 60 | -17 | 4.057 |
| 13 | Willem II | 34 | 9 | 9 | 16 | 36 | 29 | 44 | -15 | 13.142 |
| 14 | PEC Zwolle | 34 | 9 | 8 | 17 | 35 | 39 | 67 | -28 | 12.855 |
| 15 | Sparta Rotterdam | 34 | 9 | 7 | 18 | 34 | 42 | 61 | -19 | 10.261 |
| 16 | NEC ^^ | 34 | 9 | 7 | 18 | 34 | 32 | 59 | -27 | 11.174 |
| 17 | Roda JC Kerkrade ^^^ | 34 | 7 | 12 | 15 | 33 | 26 | 51 | -25 | 13.642 |
| 18 | Go Ahead Eagles ^ | 34 | 6 | 5 | 23 | 23 | 32 | 73 | -41 | 9.326 |
Wedstrijden
| R: | Datum: | Thuis: | Uit: | Sc: | Ts: | Ar: | Details: |
|---|---|---|---|---|---|---|---|
| 1 | 05/08/2016 | NEC | PEC Zwolle | 1-1 | 10.900 | Gözübüyük | 0-1 Menig, 1-1 Ofosu |
| 1 | 06/08/2016 | ADO Den Haag | Go Ahead Eagles | 3-0 | 10.168 | Higler | 1-0 (pen) en 2-0 Havenaar, 3-0 Ebuehi |
| 1 | 06/08/2016 | FC Utrecht | PSV | 2-1 | 16.329 | Nijhuis | 1-0 Haller, 1-1 Pröpper, 1-2 Pereiro |
| 1 | 06/08/2016 | FC Twente | Excelsior | 1-2 | 25.000 | Mulder | 0-1 Vermeulen, 0-2 Owusu, 1-2 Oosterwijk |
| 1 | 06/08/2016 | Willem II | Vitesse | 1-4 | 12.000 | Lindhout | 0-1 Van Wolfswinkel, 0-2 Qazaishvili, 0-3 en 0-4 Nathan, 1-4 Sol |
| 1 | 07/08/2016 | FC Groningen | Feyenoord | 0-5 | 19.000 | Van Boekel | 0-1 Vilhena, 0-2, 0-3 en 0-4 Elia, 0-5 Jørgensen, |
| 1 | 07/08/2016 | AZ | sc Heerenveen | 2-2 | 14.377 | Makkelie | 1-0 Henriksen, 1-1 Zeneli, 2-1 Weghorst (pen), 2-2 Schaars; R: Huizing (Hee) |
| 1 | 07/08/2016 | Sparta Rotterdam | Ajax | 1-3 | 10.599 | Blom | 0-1 Klaasen, 1-1 Gudelj (e.d.), 1-2 Sinkgraven, 1-3 Cassiera; R: Veltman (Aja) |
| 1 | 07/08/2016 | Roda JC Kerkrade | Heracles Almelo | 1-1 | 13.006 | Kamphuis | 0-1 Navratil, 1-1 Auassar |
| 2 | 12/08/2016 | sc Heerenveen | FC Utrecht | 2-2 | 20.850 | Manschot | 1-0 Slagveer, 1-1 Haller, 1-2 Ramselaar, 2-2 Ghoochannejhad |
| 2 | 13/08/2016 | Excelsior | FC Groningen | 2-0 | 3.000 | Gözübüyük | 1-0 Mattheij, 2-0 Vermeulen |
| 2 | 13/08/2016 | Ajax | Roda JC Kerkrade | 2-2 | 42.500 | Nijhuis | 1-0 Dolberg, 1-1 Auassar, 2-1 Dolberg, 2-2 VAn Hyfte; R: Ananou (Rod) |
| 2 | 13/08/2016 | Vitesse | ADO Den Haag | 1-2 | 10.000 | Blom | 1-0 Van Wolfswinkel, 1-1 en 1-2 Kastaneer |
| 2 | 13/08/2016 | PEC Zwolle | Sparta Rotterdam | 0-3 | 12.800 | Kamphuis | 0-1 Brogno, 0-2 Goodwin, 0-3 Brogno |
| 2 | 14/08/2016 | Heracles Almelo | Willem II | 3-1 | 10.000 | Wiedemeijer | 1-0 Bel Hassani, 2-0 en 3-0 Gladon, 3-1 Falkenburg |
| 2 | 14/08/2016 | Go Ahead Eagles | NEC | 2-2 | 9.123 | Vd Kerkhof | 0-1 Mayi, 1-1 Duits, 2-1 Ojamaa, 2-2 Mayi |
| 2 | 14/08/2016 | Feyenoord | FC Twente | 2-0 | 47.500 | Makkelie | 1-0 Toornstra, 2-0 Jørgensen |
| 2 | 14/08/2016 | PSV | AZ | 1-0 | 34.000 | Kuipers | 1-0 Moreno |
| 3 | 19/08/2016 | Excelsior | ADO Den Haag | 1-2 | 4.123 | Nijhuis | 1-0 Mattheij, 1-1 Kastaneer, 1-2 Beugelsdijk |
| 3 | 20/08/2016 | Roda JC Kerkrade | Vitesse | 0-1 | 12.000 | Makkelie | 0-1 Baker |
| 3 | 20/08/2016 | Ajax | Willem II | 1-2 | 40.000 | Higler | 1-0 Klaassen, 1-1 Falkenburg, 1-2 Sol |
| 3 | 20/08/2016 | PEC Zwolle | PSV | 0-4 | 12.700 | Van Boekel | 0-1 Isimat, 0-2 Hendrix, 0-3 L. de Jong, 0-4 Bergwijn |
| 3 | 20/08/2016 | NEC | sc Heerenveen | 2-1 | 9.500 | Vd Graaf | 1-0 Dumic, 1-1 Van Amersfoort, 2-1 Ofosu |
| 3 | 21/08/2016 | FC Groningen | FC Twente | 3-4 | 15.000 | Blom | 0-1, 0-2 en 0-3 Ünal, 1-3 Mahi, 2-3 Idrissi, 3-3 Hoesen, 3-4 Oosterwijk |
| 3 | 21/08/2016 | FC Utrecht | AZ | 1-2 | 15.570 | Liesveld | 0-1 Henriksen, 1-1 Joosten, 1-2 Jahanbakshsh |
| 3 | 21/08/2016 | Sparta Rotterdam | Go Ahead Eagles | 1-0 | 9.614 | Gözübüyük | 1-0 Brogno (pen) |
| 3 | 21/08/2016 | Heracles Almelo | Feyenoord | 0-1 | 11.307 | Kuipers | 0-1 El Ahmadi |
| 4 | 26/08/2016 | Vitesse | FC Utrecht | 1-1 | 12.105 | Kuipers | 1-0 Van Wolfswinkel, 1-1 Haller |
| 4 | 27/08/2016 | Willem II | Roda JC Kerkrade | 0-0 | 11.200 | Vd Kerkhof | |
| 4 | 27/08/2016 | sc Heerenveen | PEC Zwolle | 1-0 | 20.080 | Lindhout | 1-0 Larsson |
| 4 | 27/08/2016 | Feyenoord | Excelsior | 4-1 | 47.500 | Liesveld | 0-1 Elbers, 1-1 en 2-1 Kuyt, 3-1 Berghuis, 4-1 Toornstra |
| 4 | 27/08/2016 | FC Twente | Sparta Rotterdam | 3-1 | 25.000 | Wiedemeijer | 1-0 Ziyech, 2-0 Yeboah, 2-1 Brogno (pen), 3-1 Ziyech |
| 4 | 28/08/2016 | PSV | FC Groningen | 0-0 | 33.000 | Nijhuis | R: Bacuna (Gro) |
| 4 | 28/08/2016 | ADO Den Haag | Heracles Almelo | 1-1 | 11.016 | Higler | 0-1 Gosens, 1-1 Havenaar |
| 4 | 28/08/2016 | Go Ahead Eagles | Ajax | 0-3 | 9.756 | Van Boekel | 0-1 en 0-2 (pen) Klaasen, 0-3 Gudelj |
| 4 | 28/08/2016 | AZ | NEC | 2-0 | 13.412 | Blom | 1-0 Dos Santos, 2-0 Jahanbakhsh R: Von Haacke (NEC) |
| 5 | 10/09/2016 | AZ | Willem II | 2-0 | 13.839 | Kuipers | 1-0 Jahanbakshsh, 2-0 Garcia |
| 5 | 10/09/2016 | sc Heerenveen | FC Twente | 3-1 | 20.850 | Kamphuis | 1-0 Ghoochannejhad, 2-0 Larsson, 2-1 Celina, 3-1 Ghoochannejhad; R: ter Avest (Twe) |
| 5 | 10/09/2016 | NEC | PSV | 0-4 | 11.600 | Higler | 0-1 Ramselaar, 0-2 Pereiro, 0-3 Brenet, 0-4 De Jong |
| 5 | 11/09/2016 | Ajax | Vitesse | 1-0 | 40.000 | Higler | 1-0 Viergever; R: Kruiswijk |
| 5 | 10/09/2016 | Excelsior | Heracles Almelo | 3-1 | 4.462 | Manschot | 1-0 Karami, 2-0 Koolwijk, 3-0 Fredy, 3-1 Vermeij |
| 5 | 11/09/2016 | Feyenoord | ADO Den Haag | 3-1 | 47.500 | Gözübüyük | 1-0 Kuyt, 2-0 Jørgensen, 2-1 Marengo, 3-1 El Ahmadi |
| 5 | 11/09/2016 | FC Groningen | Sparta Rotterdam | 1-1 | 15.000 | Makkelie | 1-0 Mahi, 1-1 El Azzouzi |
| 5 | 11/09/2016 | Go Ahead Eagles | Roda JC Kerkrade | 2-0 | 9.213 | Janssen | 1-0 Brands (pen), 2-0 Maatsen |
| 5 | 10/09/2016 | PEC Zwolle | FC Utrecht | 1-1 | 12.600 | Mulder | 1-0 Ehizibue, 1-1 Haller (pen) |
| 6 | 16/09/2016 | FC Utrecht | FC Groningen | 1-5 | 15.217 | Higler | 0-1 en 0-2 Idrissi, 1-2 Zivkovic, 1-3 Hoesen, 1-4 Van Weert, 1-5 Hoesen |
| 6 | 17/09/2016 | FC Twente | ADO Den Haag | 4-1 | 24.000 | Van Boekel | 1-0 en 2-0 Ünal, 3-0 Celina, 3-1 Jansen, 4-1 Mokotjo |
| 6 | 17/09/2016 | Vitesse | Go Ahead Eagles | 2-0 | 14.170 | Kamphuis | 1-0 Van Wolfswinkel (pen), 2-0 Baker |
| 6 | 17/09/2016 | Roda JC Kerkrade | sc Heerenveen | 0-3 | 12.407 | Nijhuis | 0-1 Larsson, 0-2 Veerman, 0-3 Zeneli R: Ajagun, Kum (Rod), Facey (Hee) |
| 6 | 17/09/2016 | Willem II | Excelsior | 1-1 | 11.500 | Liesveld | 1-0 Sol, 1-1 Faik |
| 6 | 18/09/2016 | Sparta Rotterdam | NEC | 2-0 | 10.032 | Janssen | 1-0 Verhaar, 2-0 El Azzouzi |
| 6 | 18/09/2016 | PEC Zwolle | AZ | 0-2 | 12.900 | Makkelie | 0-1 Weghorst, 0-2 Til |
| 6 | 18/09/2016 | PSV | Feyenoord | 0-1 | 35.000 | Blom | 0-1 Botteghin |
| 6 | 18/09/2016 | Heracles Almelo | Ajax | 0-2 | 12.032 | Gözübüyük | 0-1 Klaassen, 0-2 Gudelj |
| 7 | 24/09/2016 | ADO Den Haag | sc Heerenveen | 0-3 | 10.572 | Wiedemeijer | 0-1 Kanon (e.d.), 0-2 Zeneli, 0-4 Veerman |
| 7 | 24/09/2016 | FC Groningen | Heracles Almelo | 0-0 | 18.272 | Janssen | |
| 7 | 24/09/2016 | Ajax | PEC Zwolle | 5-1 | 48.088 | Kamphuis | 0-1 Brama, 1-1 en 2-1 Sanchez, 3-1 Dolberg, 4-1 Traoré, 5-1 Dolberg |
| 7 | 24/09/2016 | AZ | Go Ahead Eagles | 2-2 | 13.774 | Nijhuis | 1-0 (pen) en 2-0 Weghorst, 2-1 Duits, 2-2 Hendriks |
| 7 | 24/09/2016 | Excelsior | PSV | 1-3 | 4.400 | Makkelie | 0-1 Narsingh, 1-1 Bruins (pen), 1-2 L. de Jong, 1-3 Pröpper |
| 7 | 25/09/2016 | NEC | Willem II | 0-0 | 10.800 | Gözübüyük | |
| 7 | 25/09/2016 | FC Twente | Vitesse | 2-1 | 22.000 | Manschot | 1-0 Ünal, 2-0 Celina, 2-1 Baker |
| 7 | 25/09/2016 | FC Utrecht | Sparta Rotterdam | 2-0 | 19.077 | Blom | 1-0 Zivkovic, 2-0 Barazite |
| 7 | 25/09/2016 | Feyenoord | Roda JC Kerkrade | 5-0 | 45.000 | Kuipers | 1-0 Jørgensen, 2-0 El Ahmadi, 3-0 Jørgensen, 4-0 Toornstra, 5-0 Kongolo |
| 8 | 30/09/2016 | PEC Zwolle | ADO Den Haag | 2-1 | 12.400 | Kuipers | 0-1 Trybull, 1-1 en 2-1 Mokhtar R: Trybull (ADO) |
| 8 | 01/10/2016 | Vitesse | FC Groningen | 2-1 | 15.055 | Wiedemeijer | 0-1 Hoesen (pen), 1-1 Baker, 2-1 leerdam |
| 8 | 01/10/2016 | sc Heerenveen | PSV | 1-1 | 23.650 | Van Boekel | 1-0 Zeneli, 1-1 St. Juste (e.d.) |
| 8 | 01/10/2016 | Roda JC Kerkrade | NEC | 0-1 | 11.915 | Blom | 0-1 Mayi |
| 8 | 01/10/2016 | Go Ahead Eagles | Excelsior | 3-0 | 9.122 | Vd Graaf | 1-0 Duits, 2-0 en 3-0 Hendriks (pen) R: Pantic (Exc) |
| 8 | 02/10/2016 | Ajax | FC Utrecht | 3-2 | 45.000 | Nijhuis | 0-1 Conboy, 1-1 Leeuwin (e.d.), 2-1 Schöne (pen), 3-1 Ziyech, 3-2 Van der Maarel |
| 8 | 02/10/2016 | Willem II | Feyenoord | 0-2 | 13.000 | Higler | 0-1 Jørgensen, 0-2 Tapia |
| 8 | 02/10/2016 | Heracles Almelo | FC Twente | 1-1 | 12.052 | Makkelie | 0-1 Klich (pen), 1-1 Armenteros |
| 8 | 02/10/2016 | Sparta Rotterdam | AZ | 1-1 | 10.261 | Liesveld | 0-1 Til, 1-1 Breuer; R: Dumfries (Spa) |
| 9 | 15/10/2016 | Sparta Rotterdam | Willem II | 2-2 | 10.500 | Van Boekel | 0-1 en 0-2 Sol, 1-2 Goodwin, 2-2 Verhaar |
| 9 | 15/10/2016 | FC Utrecht | Go Ahead Eagles | 3-0 | 17.433 | Janssen | 1-0 Troupée, 2-0 Strieder, 3-0 Zivkovic |
| 9 | 15/10/2016 | PSV | Heracles Almelo | 1-1 | 33.000 | Nijhuis | 0-1 Armenteros, 1-1 Pereiro |
| 9 | 16/10/2016 | ADO Den Haag | Ajax | 0-2 | 13.764 | Blom | 0-1 Klaassen, 0-2 Traoré |
| 9 | 15/10/2016 | AZ | Vitesse | 2-2 | 15.415 | Gözübüyük | 0-1 Baker, 0-2 Van Wolfswinkel (pen), 1-2 en 2-2 Mühren |
| 9 | 16/10/2016 | FC Twente | PEC Zwolle | 2-2 | 24.900 | Higler | 1-0 Klich (pen), 1-1 Mokhtar, 2-1 Ünal, 2-2 Warmerdam |
| 9 | 16/10/2016 | Excelsior | Roda JC Kerkrade | 0-1 | 3.544 | Kamphuis | 0-1 Boysen |
| 9 | 16/10/2016 | NEC | Feyenoord | 1-2 | 11.110 | Makkelie | 1-0 Rayhi, 1-1 Jørgensen, 1-2 Kramer |
| 9 | 15/10/2016 | FC Groningen | sc Heerenveen | 0-3 | 20.000 | Liesveld | 0-1 Zeneli, 0-2 Larsson, 0-3 Ghoochannejhad R: Davidson |
| 10 | 21/10/2016 | Excelsior | PEC Zwolle | 0-2 | 3.640 | Lindhout | 0-1 Menig, 0-2 Warmerdam |
| 10 | 22/10/2016 | Go Ahead Eagles | FC Twente | 0-2 | 9.733 | Vd Kerkhof | 0-1 Yeboah, 0-2 Celina; R: Antonia (GoA) |
| 10 | 22/10/2016 | PSV | Sparta Rotterdam | 1-0 | 33.800 | Kamphuis | 1-0 Ramselaar |
| 10 | 22/10/2016 | Roda JC Kerkrade | ADO Den Haag | 1-1 | 16.178 | Janssen | 0-1 Duplan, 1-1 Paulissen |
| 10 | 22/10/2016 | Willem II | FC Utrecht | 0-1 | 11.410 | Wiedemeijer | 0-1 Haller; R: Sol (Wil) |
| 10 | 23/10/2016 | NEC | Vitesse | 1-1 | 12.100 | Van Boekel | 0-1 Foor, 1-1 Dumic |
| 10 | 23/10/2016 | Feyenoord | Ajax | 1-1 | 47.500 | Kuipers | 0-1 Dolberg, 1-1 Kuyt |
| 10 | 23/10/2016 | FC Groningen | AZ | 2-0 | 17.500 | Higler | 1-0 Linssen, 2-0 VAn Weert |
| 10 | 23/10/2016 | sc Heerenveen | Heracles Almelo | 3-1 | 21.000 | Blom | 1-0 Marzo, 1-1 Kuwas, 2-1 Larsson, 3-1 St Juste |
| 11 | 28/10/2016 | FC Twente | Roda JC Kerkrade | 0-0 | 24.000 | Liesveld | |
| 11 | 29/10/2016 | Willem II | FC Groningen | 2-1 | 12.700 | Higler | 1-0 Haye, 1-1 Mahi, 2-1 Ogbeche |
| 11 | 29/10/2016 | Heracles Almelo | Sparta Rotterdam | 2-2 | 11.337 | Janssen | 0-1 El Azzouzi, 1-1 Darri, 2-1 Kuwas, 2-2 Brogno |
| 11 | 29/10/2016 | Vitesse | PSV | 0-2 | 18.452 | Kuipers | 0-1 en 0-2 Pereiro |
| 11 | 29/10/2016 | Ajax | Excelsior | 1-0 | 47.460 | Makkelie | 1-0 Ziyech |
| 11 | 30/10/2016 | PEC Zwolle | Go Ahead Eagles | 3-1 | 13.200 | Gözübüyük | 1-0 Menig, 1-1 Fischer, 2-1 Saymak, 3-1 Holla; R: Fischer (GoA) |
| 11 | 30/10/2016 | Feyenoord | sc Heerenveen | 2-2 | 47.500 | Van Boekel | 0-1 Ghoochannejhad, 1-1 Jørgensen, 2-1 Karsdorp, 2-2 Zeneli |
| 11 | 30/10/2016 | FC Utrecht | NEC | 1-1 | 16.911 | Vd Graaf | 1-0 Delle (e.d.), 1-1 Kadioglu |
| 11 | 30/10/2016 | ADO Den Haag | AZ | 0-1 | 11.023 | Kamphuis | 0-1 Mühren |
| 12 | 04/11/2016 | Sparta Rotterdam | sc Heerenveen | 3-1 | 10.423 | Wiedemeijer | 0-1 St Juste, 1-1 Spierings, 2-1 El Azzouzi, 3-1 Goodwin |
| 12 | 05/11/2016 | ADO Den Haag | Willem II | 1-0 | 10.044 | Mulder | 1-0 Beugelsdijk |
| 12 | 05/11/2016 | PSV | FC Twente | 1-1 | 33.500 | Gözübüyük | 0-1 Ünal,1-1 Moreno |
| 12 | 05/11/2016 | NEC | FC Groningen | 1-1 | 10.750 | Janssen | 0-1 Van Weert, 1-1 Kadioglu |
| 12 | 05/11/2016 | PEC Zwolle | Roda JC Kerkrade | 0-0 | 12.600 | Kuipers | |
| 12 | 06/11/2016 | FC Utrecht | Excelsior | 2-1 | 18.648 | Liesveld | 1-0 Ayoub, 2-0 Barazite, 2-1 Elbers |
| 12 | 06/11/2016 | AZ | Ajax | 2-2 | 16.647 | Van Boekel | 1-0 Weghorst, 1-1 Traoré, 1-2 Klaassen, 2-2 Weghorst |
| 12 | 06/11/2016 | Vitesse | Heracles Almelo | 1-2 | 13.743 | Makkelie | 1-0 Van Wolfswinkel, 1-1 Darri, 1-2 Armenteros (pen) |
| 12 | 06/11/2016 | Go Ahead Eagles | Feyenoord | 1-0 | 9.781 | Nijhuis | 1-0 Antonia |
| 13 | 19/11/2016 | sc Heerenveen | Vitesse | 1-1 | 24.465 | Janssen | 0-1 Baker, 1-1 Veerman |
| 13 | 19/11/2016 | Heracles Almelo | Go Ahead Eagles | 2-1 | 11.853 | Van Boekel | 0-1 Antonia, 1-1 en 2-1 Armenteros |
| 13 | 19/11/2016 | Willem II | PSV | 0-0 | 13.650 | Liesveld | |
| 13 | 20/11/2016 | Ajax | NEC | 5-0 | 45.000 | Nijhuis | 1-0, 2-0 en 3-0 Dolberg, 4-0 Traoré, 5-0 Schöne |
| 13 | 19/11/2016 | Excelsior | Sparta Rotterdam | 3-2 | 4.400 | Kuipers | 0-1 Brogno, 1-1 Elbers, 2-1 Fredy, 3-1 Hasselbaink (pen), 3-2 Dumfries |
| 13 | 20/11/2016 | Roda JC Kerkrade | AZ | 1-1 | 13.000 | Manschot | 1-0 Ajagun, 1-1 Weghorst |
| 13 | 20/11/2016 | FC Twente | FC Utrecht | 1-1 | 25.000 | Liesveld | 1-0 Ter Avest, 1-1 Zivkovic; R: Leeuwin (Utr) |
| 13 | 19/11/2016 | FC Groningen | ADO Den Haag | 2-1 | 13.000 | Blom | 1-0 Hateboer, 1-1 Duplan, 2-1 Van Weert |
| 13 | 20/11/2016 | Feyenoord | PEC Zwolle | 3-0 | 47.500 | Higler | 1-0 Kuyt, 2-0 El Ahmadi, 3-0 Toornstra |
| 14 | 25/11/2016 | Go Ahead Eagles | Willem II | 0-1 | 9.397 | Manschot | 0-1 Schuurman |
| 14 | 26/11/2016 | Vitesse | Excelsior | 2-2 | 14.328 | Mulder | 0-1 en 0-2 Faik, 1-2 Van Wolfswinkel (pen), 2-2 Tighadouini |
| 14 | 26/11/2016 | PSV | ADO Den Haag | 3-1 | 32.700 | Kuipers | 1-0 Pereiro (pen), 2-0 Beugelsdijk (e.d.), 3-0 L. de Jong, 3-1 Beugelsdijk (pen) |
| 14 | 26/11/2016 | PEC Zwolle | FC Groningen | 0-4 | 13.000 | Van Boekel | 0-1 Tibbling, 0-2 Van Weert, 0-3 Rusnak, 0-4 Mahi |
| 14 | 26/11/2016 | NEC | FC Twente | 3-2 | 11.092 | Higler | 1-0 en 2-0 Grot, 2-1 Ünal, 3-1 Dumic, 3-2 Dyrestam (e.d.) |
| 14 | 27/11/2016 | Sparta Rotterdam | Roda JC Kerkrade | 2-2 | 10.100 | Janssen | 0-1 Kum, 0-2 Mitidis, 1-2 Brogno, 2-2 Dougall |
| 14 | 27/11/2016 | AZ | Heracles Almelo | 5-1 | 15.738 | Blom | 1-0 Mühren, 2-0 Weghorst, 3-0 Mühren, 3-1 Armenteros (pen), 4-1 Dos Santos, 5-1 Jahanbakshsh |
| 14 | 27/11/2016 | sc Heerenveen | Ajax | 0-1 | 25.800 | Makkelie | 0-1 Klaassen |
| 14 | 27/11/2016 | FC Utrecht | Feyenoord | 3-3 | 19.233 | Gözübüyük | 1-0 Haller, 1-1 Kuyt, 2-1 Troupeé, 3-1 Haller, 3-2 Jørgensen, 3-3 Kramer |
| 15 | 02/12/2016 | Heracles Almelo | NEC | 2-0 | 10.783 | Manschot | 1-0 Duarte, 2-0 Armenteros |
| 15 | 03/12/2016 | Go Ahead Eagles | sc Heerenveen | 1-3 | 9.187 | Lindhout | 1-0 Maatsen, 1-1 en 1-2 Ghoochannejhad, 1-3 Kobayashi |
| 15 | 03/12/2016 | Excelsior | AZ | 3-3 | 3.670 | Higler | 1-0 Elbers, 1-1 Mühren, 2-1 Hasselbaink (pen), 2-2 Tankovic, 3-2 Faik, 3-3 Wuytens |
| 15 | 03/12/2016 | Roda JC Kerkrade | PSV | 0-0 | 14.017 | Blom | |
| 15 | 04/12/2016 | Ajax | FC Groningen | 2-0 | 45.000 | Gözübüyük | 1-0 Sanchez, 2-0 Ziyech (pen) |
| 15 | 04/12/2016 | ADO Den Haag | FC Utrecht | 0-2 | 8.956 | Van Boekel | 0-1 Barazite, 0-2 Haller; R: Beugelsdijk (ADO) |
| 15 | 04/12/2016 | Feyenoord | Sparta Rotterdam | 6-1 | 47.500 | Nijhuis | 1-0 Vilhena, 2-0 Toornstra, 3-0 en 4-0 Jørgensen, 5-0 Botteghin, 5-1 Verhaar, 6-1 Elia |
| 15 | 04/12/2016 | Willem II | FC Twente | 0-0 | 11.450 | Janssen | |
| 15 | 03/12/2016 | Vitesse | PEC Zwolle | 3-1 | 14.173 | Kamphuis | 1-0 Baker (pen), 2-0 Zhang, 2-1 Schenkeveld, 3-1 Nathan |
| 16 | 09/12/2016 | FC Groningen | Roda JC Kerkrade | 2-0 | 17.500 | Vd Kerkhof | 1-0 Mahi, 2-0 Sorloth |
| 16 | 10/12/2016 | NEC | ADO Den Haag | 3-0 | 11.000 | Kamphuis | 1-0 Mayi, 2-0 Ehibue (e.d.), 3-0 Rayhi |
| 16 | 10/12/2016 | PSV | Go Ahead Eagles | 1-0 | 33.000 | Janssen | 1-0 S. de Jong |
| 16 | 10/12/2016 | sc Heerenveen | Excelsior | 2-1 | 21.600 | Van Boekel | 0-1 Hasselbaink (pen), 1-1 en 2-1 Larsson |
| 16 | 10/12/2016 | PEC Zwolle | Willem II | 0-0 | 11.200 | Blom | |
| 16 | 11/12/2016 | Sparta Rotterdam | Vitesse | 0-1 | 10.353 | Lindhout | 0-1 Van Wolfswinkel; R: Spierings (Spa) |
| 16 | 11/12/2016 | AZ | Feyenoord | 0-4 | 15.555 | Kuipers | 0-1 Berghuis, 0-2 Van der Heijden, 0-3 Jørgensen, 0-4 Vilhena |
| 16 | 11/12/2016 | FC Utrecht | Heracles Almelo | 2-0 | 17.429 | Nijhuis | 1-0 Te Wierik (e.d.), 2-0 Haller (pen) R: Breukers (Her) |
| 16 | 11/12/2016 | FC Twente | Ajax | 1-0 | 27.800 | Higler | 1-0 Klich (pen); R: Viergever (Aja) |
| 17 | 16/12/2016 | Willem II | sc Heerenveen | 2-1 | 11.450 | Vd Kerkhof | 1-0 Sol, 1-1 Heerkens (e.d.), 2-1 Sol |
| 17 | 17/12/2016 | Roda JC Kerkrade | FC Utrecht | 0-0 | 13.254 | Lindhout | |
| 17 | 17/12/2016 | Feyenoord | Vitesse | 3-1 | 47.500 | Higler | 1-0 Elia, 1-1 Tighadouini, 2-1 en 3-1 Berghuis |
| 17 | 18/12/2016 | ADO Den Haag | Sparta Rotterdam | 1-0 | 12.691 | Blom | 1-0 Becker; R: Hevel (ADO) |
| 17 | 18/12/2016 | Heracles Almelo | PEC Zwolle | 3-0 | 11.102 | Vd Graaf | 1-0 Armenteros (pen), 2-0 Vermeij, 3-0 V. Mieghem; R: Schenkeveld, V. Polen (PEC) |
| 17 | 18/12/2016 | Excelsior | NEC | 2-2 | 3.875 | Bax | 1-0 Elbers, 1-1 Grot, 2-1 Karami, 2-2 Dumic |
| 17 | 18/12/2016 | FC Twente | AZ | 1-2 | 24.500 | Kamphuis | 0-1 Weghorst, 1-1 Ünal, 1-2 Bijen (e.d.) |
| 17 | 18/12/2016 | FC Groningen | Go Ahead Eagles | 1-1 | 17.500 | Nijhuis | 1-0 Mahi, 1-1 Antonia |
| 17 | 18/12/2016 | Ajax | PSV | 1-1 | 51.998 | Van Boekel | 1-0 Klaassen, 1-1 S. de Jong |
| 18 | 13/01/2017 | Go Ahead Eagles | AZ | 1-3 | 9.518 | Makkelie | 0-1 Weghorst, 0-2 Jahanbakhsh, 1-2 Antonia (p), 1-3 Jahanbakhsh |
| 18 | 14/01/2017 | sc Heerenveen | ADO Den Haag | 2-0 | 20.400 | Kamphuis | 1-0 en 2-0 Ghoochannejhad |
| 18 | 14/01/2017 | Heracles Almelo | FC Groningen | 1-4 | 9.500 | Van Boekel | 0-1 Mahi, 0-2 Payne, 0-3 Sörloth, 0-4 Mahi, 1-4 Van Mieghem |
| 18 | 14/01/2017 | PSV | Excelsior | 2-0 | 27.500 | Kuipers | 1-0 Van Ginkel, 2-0 Pröpper |
| 18 | 14/01/2017 | Sparta Rotterdam | FC Utrecht | 1-2 | 10.510 | Gözübüyük | 1-0 Calero, 1-1 Janssen, 1-2 Peterson |
| 18 | 15/01/2017 | Roda JC Kerkrade | Feyenoord | 0-2 | 14.475 | Blom | 0-1 Kuyt, 0-2 Elia |
| 18 | 15/01/2017 | PEC Zwolle | Ajax | 1-3 | 13.250 | Higler | 0-1 Schöne (pen), 0-2 Ziyech, 1-2 Brock-Madsen, 1-3 Ziyech |
| 18 | 15/01/2017 | Vitesse | FC Twente | 3-1 | 15.194 | Janssen | 1-0 Baker, 2-0 Van Wolfswinkel, 3-0 Rashica, 1-3 Klich (pen); R: Baker |
| 18 | 15/01/2017 | Willem II | NEC | 0-1 | 12.400 | Mulder | 0-1 Grot |
| 19 | 20/01/2017 | FC Twente | Heracles Almelo | 1-0 | 28.600 | Makkelie | 1-0 Andersen |
| 19 | 21/01/2017 | AZ | Sparta Rotterdam | 1-1 | 15.910 | Higler | 1-0 Luckassen, 1-1 Pogba |
| 19 | 21/01/2017 | ADO Den Haag | PEC Zwolle | 1-2 | 9.130 | Bax | 1-0 Kastaneer, 1-1 Ehizibue, 1-2 Brock-Madsen |
| 19 | 21/01/2017 | Feyenoord | Willem II | 1-0 | 47.500 | Janssen | 1-0 Toornstra |
| 19 | 21/01/2017 | FC Groningen | Vitesse | 1-1 | 15.000 | Manschot | 1-0 Leerdam (e.d.), 1-1 Foor; R: Foor (Vit) |
| 19 | 22/01/2017 | FC Utrecht | Ajax | 0-1 | 21.009 | Kuipers | 0-1 Schöne |
| 19 | 22/01/2017 | Excelsior | Go Ahead Eagles | 1-1 | 3.975 | Blom | 0-1 Chirivella, 1-1 Hasaselbaink |
| 19 | 22/01/2017 | NEC | Roda JC Kerkrade | 2-0 | 11.533 | Vd Graaf | 1-0 en 2-0 Breinburg (pen) |
| 19 | 22/01/2017 | PSV | sc Heerenveen | 4-3 | 33.900 | Nijhuis | 0-1 Ghoochannejhad, 1-1 Pröpper, 2-1 Pereiro, 2-2 en 2-3 Ghoochannejhad, 3-3 Van Ginkel, 4-3 Moreno |
| 20 | 27/01/2017 | Willem II | Sparta Rotterdam | 3-2 | 12.300 | Manschot | 1-0 Sol, 1-1 El Azzouzi, 2-1 Lachman, 2-2 Verhaar, 3-2 Haye |
| 20 | 28/01/2017 | Go Ahead Eagles | FC Utrecht | 0-1 | 9.645 | Vd Graaf | 0-1 Schenk (e.d.), R: Maatsen (GoA) |
| 20 | 28/01/2017 | Heracles Almelo | PSV | 1-2 | 11.245 | Blom | 0-1 Ramselaar, 1-1 Armenteros, 1-2 Pröpper |
| 20 | 28/01/2017 | Roda JC Kerkrade | Excelsior | 4-0 | 11.858 | Gözübüyük | 1-0 Schahin, 2-0 Paulissen, 3-0 Papazoglou, 4-0 Paulissen; R: Mattheij (Exc) |
| 20 | 29/01/2017 | Vitesse | AZ | 2-1 | 14.183 | Kamphuis | 1-0 Baker, 2-0 Nathan, 2-1 Kashia (e.d.) |
| 20 | 29/01/2017 | sc Heerenveen | FC Groningen | 0-0 | 21.750 | Janssen | |
| 20 | 29/01/2017 | Ajax | ADO Den Haag | 3-0 | 45.000 | Nijhuis | 1-0 Ziyech, 2-0 Schöne, 3-0 Dolberg |
| 20 | 29/01/2017 | PEC Zwolle | FC Twente | 1-2 | 12.800 | Vd Kerkhof | 0-1 Seys, 0-2 Menig, 1-2 Assaidi R: Celina (Twe) |
| 20 | 29/01/2017 | Feyenoord | NEC | 4-0 | 47.500 | Van Boekel | 1-0 Berghuis, 2-0 Elia, 3-0 en 4-0 Jørgensen |
| 21 | 03/02/2017 | ADO Den Haag | Vitesse | 0-2 | 11.343 | S. Mulder | 0-1 Tighadouini, 0-2 Van Wolfswinkel |
| 21 | 04/02/2017 | NEC | Go Ahead Eagles | 1-2 | 11.600 | Kuipers | 0-1 Manu, 0-2 Antonia, 1-2 Grot; R: Manu (GoA) |
| 21 | 04/02/2017 | AZ | PSV | 2-4 | 16.079 | Gözübüyük | 0-1 en 0-2 Willems, 1-2 Friday, 1-3 Pereiro, 1-4 L. de Jong, 2-4 Friday; R: Wuytens (AZ) |
| 21 | 04/02/2017 | Willem II | Heracles Almelo | 1-3 | 12.800 | Lindhout | 1-0 Sol (pen), 1-1 Van Ooijen, 1-2 Peterson, 1-3 Gosens; R: Castro (Her) |
| 21 | 04/02/2017 | FC Groningen | Excelsior | 1-1 | 12.500 | Vd Graaf | 1-0 Mahi (pen), 1-1 Hadouir |
| 21 | 05/02/2017 | Roda JC Kerkrade | Ajax | 0-2 | 17.112 | Makkelie | 0-1Klaassen, 0-2 Younes |
| 21 | 05/02/2017 | FC Twente | Feyenoord | 0-2 | 27.000 | Higler | 0-1 Botteghin, 0-2 Jørgensen |
| 21 | 05/02/2017 | Sparta Rotterdam | PEC Zwolle | 2-3 | 10.131 | Nijhuis | 0-1 Menig, 0-2 Brock-Madsen, 0-3 Israelsson, 1-3 en 2-3 Pogba; R: Schenkeveld (PEC) |
| 21 | 05/02/2017 | FC Utrecht | sc Heerenveen | 1-0 | 18.078 | Kamphuis | 1-0 Ludwig; R: Larsson (Hee), Ludwig (Utr) |
| 22 | 10/02/2017 | PEC Zwolle | NEC | 2-0 | 13.200 | Manschot | 1-0 Brock-Madsen, 2-0 Menig |
| 22 | 11/02/2017 | Heracles Almelo | Roda JC Kerkrade | 2-2 | 10.457 | Kuipers | 0-1 Paulissen, 0-2 Van Hyfte, 1-2 en 2-2 Armenteros |
| 22 | 11/02/2017 | Go Ahead Eagles | ADO Den Haag | 3-1 | 9.647 | Janssen | 1-0 en 2-0 Hendriks, 2-1 El Khayati (pen), 3-1 Ritzmaier; R: Setkus (ADO) |
| 22 | 11/02/2017 | Feyenoord | FC Groningen | 2-0 | 47.500 | Gözübüyük | 1-0 en 2-0 Toornstra; R: Bacuna (Gro) |
| 22 | 11/02/2017 | Vitesse | Willem II | 0-2 | 14.879 | Vd Kerkhof | 0-1 Koppers, 0-2 Oularé |
| 22 | 12/02/2017 | Excelsior | FC Twente | 1-1 | 4.275 | Makkelie | 1-0 Hasselbaink, 1-1 F. Jensen |
| 22 | 12/02/2017 | Ajax | Sparta Rotterdam | 2-0 | 45.000 | Van Boekel | 1-0 Traoré, 2-0 Dolberg |
| 22 | 12/02/2017 | sc Heerenveen | AZ | 1-2 | 21.250 | Nijhuis | 0-1 Tankovic, 0-2 Bel Hassani, 1-2 Ghoochannejhad; R: St. Juste (Hee) |
| 22 | 12/02/2017 | PSV | FC Utrecht | 3-0 | 33.400 | Higler | 1-0 L. de Jong, 2-0 Bergwijn, 3-0 Van Ginkel |
| 23 | 17/02/2017 | Roda JC Kerkrade | Go Ahead Eagles | 1-0 | 13.029 | Van Boekel | 1-0 Kum |
| 23 | 18/02/2017 | FC Twente | sc Heerenveen | 1-0 | 25.000 | Gözübüyük | 1-0 Klich (pen.) |
| 23 | 19/02/2017 | Willem II | AZ | 1-1 | 11.650 | Higler | 0-1 Luckassen, 1-1 Falkenburg |
| 23 | 18/02/2017 | PSV | NEC | 3-1 | 33.500 | Kamphuis | 1-0 Van Ginkel (pen), 1-1 Massaoud, 2-1 Ramselaar, 3-1 Luuk de Jong |
| 23 | 18/02/2017 | FC Utrecht | PEC Zwolle | 3-1 | 18.349 | Janssen | 1-0 Van Polen (e.d), 2-0 Kerk, 3-0 Barazite, 3-1 Brock-Madsen |
| 23 | 19/02/2017 | Heracles Almelo | Excelsior | 4-0 | 10.322 | S. Mulder | 1-0 Kuwas, 2-0 Bruns, 3-0 te Wierik, 4-0 Peterson; R: mattheij (Exc) |
| 23 | 19/02/2017 | Vitesse | Ajax | 0-1 | 20.016 | Blom | 0-1 Klaassen |
| 23 | 19/02/2017 | Sparta Rotterdam | FC Groningen | 2-2 | 9.778 | Lindhout | 1-0 Van Moorsel, 2-0 Calero, 2-1 Janssen, 2-2 Mahi; R:Bacuna (Gro) |
| 23 | 19/02/2017 | ADO Den Haag | Feyenoord | 0-1 | 12.822 | Kuipers | 0-1 El Ahmadi |
| 24 | 24/02/2017 | ADO Den Haag | FC Twente | 1-1 | 11.615 | Blom | 1-0 Schaken, 1-1 Ünal |
| 24 | 25/02/2017 | FC Groningen | FC Utrecht | 2-3 | 17.500 | Makkelie | 1-0 en 2-0 Linssen, 2-1 Haller. 2-2 Troupee, 2-3 Ayoub |
| 24 | 26/02/2017 | AZ | PEC Zwolle | 1-1 | 14.787 | Van Boekel | 0-1 Thomas, 1-1 Friday |
| 24 | 25/02/2017 | Excelsior | Willem II | 0-2 | 4.075 | Janssen | 0-1 Koppers, 0-2 Falkenburg; R: Pantic (Exc) |
| 24 | 25/02/2017 | sc Heerenveen | Roda JC Kerkrade | 3-0 | 22.100 | Mulder | 1-0 Schmidt, 2-0 Veerman, 3-0 Ghoochannejhad R: El Makrini (Rod) |
| 24 | 26/02/2017 | Go Ahead Eagles | Vitesse | 1-3 | 9.412 | Kamphuis | 0-1 Van Wolfswinkel, 0-2 Foor, 0-3 Rashica, 1-3 Crowley |
| 24 | 25/02/2017 | Feyenoord | PSV | 2-1 | 47.500 | Nijhuis | 1-0 Toornstra, 1-1 Pereiro, 2-1 Zoet (e.d.) |
| 24 | 24/02/2017 | NEC | Sparta Rotterdam | 0-1 | 9.000 | Vd Kerkhof | 0-1 Van Moorsel |
| 24 | 25/02/2017 | Ajax | Heracles Almelo | 4-1 | 45.000 | Gözübüyük | 1-0 Dolberg, 1-1 Armenteros, 2-1 De Ligt, 3-1 Sanchez, 4-1 Traoré |
| 25 | 05/03/2017 | AZ | Excelsior | 1-1 | 13.863 | Kuipers | 1-0 Hahn (e.d.), 1-1 Van Duinen |
| 25 | 04/03/2017 | FC Twente | Willem II | 2-1 | 25.000 | Kamphuis | 1-0 Lachman (e.d.), 2-0 Ünal, 2-1 Croux |
| 25 | 04/03/2017 | PSV | Roda JC Kerkrade | 4-0 | 34.000 | Janssen | 1-0 Moreno, 2-0 S. de Jong, 3-0 Moreno, 4-0 S. de Jong (pen) |
| 25 | 03/03/2017 | sc Heerenveen | Go Ahead Eagles | 2-2 | 20.500 | Vd Graaf | 0-1 Hendriks, 1-1 Veerman, -1 Slagveer, 2-2 De Kogel |
| 25 | 04/03/2017 | PEC Zwolle | Vitesse | 3-1 | 13.000 | Lindhout | 1-0 Saymak, 2-0 Brock-Madsen, 2-1 Van Wolfswinkel, 3-1 Holla |
| 25 | 05/03/2017 | Sparta Rotterdam | Feyenoord | 1-0 | 10.500 | Makkelie | 1-0 Pogba |
| 25 | 05/03/2017 | FC Groningen | Ajax | 1-1 | 20.000 | Nijhuis | 1-0 Linssen, 1-1 Klaassen; R: Memisevic (Gro) |
| 25 | 05/03/2017 | FC Utrecht | ADO Den Haag | 1-1 | 17.712 | Gözübüyük | 0-1 Malone, 1-1 Zivkovic |
| 25 | 05/03/2017 | NEC | Heracles Almelo | 3-1 | 11.000 | Van Boekel | 0-1 Armenteros (pen), 1-1 Von Haacke, 2-1 Heinloth, 3-1 Hoogma (e.d.) |
| 26 | 10/03/2017 | Vitesse | Sparta Rotterdam | 5-0 | 13.852 | Manschot | 1-0 Van Wolfswinkel, 2-0 Foor, 3-0 Kruijswijk, 4-0 Nakamba, 5-0 Kashia |
| 26 | 11/03/2017 | ADO Den Haag | NEC | 1-0 | 10.256 | Nijhuis | 1-0 Havenaar |
| 26 | 11/03/2017 | Go Ahead Eagles | PSV | 1-3 | 9.752 | Blom | 0-1 S. de Jong (pen), 1-1 Manu, 1-2 L. de Jong, 1-3 Guardado |
| 26 | 11/03/2017 | Heracles Almelo | FC Utrecht | 2-1 | 10.829 | Kamphuis | 0-1 Ayoub, 1-1 Kuwas, 2-1 Bruns |
| 26 | 11/03/2017 | Excelsior | sc Heerenveen | 4-1 | 4.225 | Bax | 1-0 Elbers, 2-0 Mattheij, 3-0 Massop, 3-1 Slagveer, 4-1 Hasselbaink |
| 26 | 12/03/2017 | Willem II | PEC Zwolle | 2-0 | 13.500 | Kuipers | 1-0 Falkenburg, 2-0 Haye |
| 26 | 12/03/2017 | Feyenoord | AZ | 5-2 | 47.500 | Van Boekel | 1-0 Jørgensen, 2-0 Toornstra, 3-0 Kuyt, 3-1 Luckassen, 4-1 en 5-1 (pen) Jørgensen, 5-2 Weghorst |
| 26 | 12/03/2017 | Roda JC Kerkrade | FC Groningen | 3-1 | 11.500 | Vd Kerkhof | 1-0 Ajagun, 2-0 Kum, 3-0 Schahin, 3-1 Linssen R: Linssen (Gro) |
| 26 | 12/03/2017 | Ajax | FC Twente | 3-0 | 50.000 | Makkelie | 1-0 Younes, 2-0 en 3-0 Dolberg |
| 27 | 17/03/2017 | Roda JC Kerkrade | FC Twente | 0-3 | 13.221 | Bax | 0-1 en 0-2 Jensen, 0-3 Ünal |
| 27 | 18/03/2017 | FC Groningen | Willem II | 1-1 | 15.000 | Vd Graaf | 1-0 Jenssen, 1-1 Oulare |
| 27 | 18/03/2017 | NEC | FC Utrecht | 0-3 | 11.680 | S. Mulder | 0-1 Labyad, 0-2 Ayoub, 0-3 Haller |
| 27 | 18/03/2017 | PSV | Vitesse | 1-0 | 33.900 | Kuipers | 1-0 S. de Jong |
| 27 | 19/03/2017 | AZ | ADO Den Haag | 4-0 | 14.126 | Janssen | 1-0 en 2-0 Dos Santos, 3-0 Van Overeem, 4-0 Friday |
| 27 | 19/03/2017 | sc Heerenveen | Feyenoord | 1-2 | 25.800 | Higler | 1-0 Ghoochannejhad, 1-1 Jørgensen, 1-2 Vilhena |
| 27 | 19/03/2017 | Go Ahead Eagles | PEC Zwolle | 1-3 | 9.752 | Makkelie | 1-0 Chivrella, 1-1 Menig, 1-2 Warmerdam, 1-3 Van Polen (pen) |
| 27 | 19/03/2017 | Excelsior | Ajax | 1-1 | 4.400 | Van Boekel | 1-0 Tete (e.d.), 1-1 Kluivert |
| 27 | 18/03/2017 | Sparta Rotterdam | Heracles Almelo | 3-1 | 9.712 | Nijhuis | 1-0 Sanusi, 2-0 en 3-0 Pusic, 3-1 Pelupessy |
| 28 | 01/04/2017 | AZ | FC Groningen | 0-0 | 14.828 | Blom | |
| 28 | 01/04/2017 | PEC Zwolle | Excelsior | 1-1 | 13.140 | Kamphuis | 1-0 Warmerdam, 1-1 Bruins |
| 28 | 01/04/2017 | Sparta Rotterdam | PSV | 0-2 | 10.606 | Makkelie | 0-1 Locadia, 0-2 Van Ginkel |
| 28 | 01/04/2017 | Heracles Almelo | sc Heerenveen | 4-1 | 10.912 | Vd Kerkhof | 0-1 Ghoochannejhad (pen), 1-1 Niemeijer, 2-1 Armenteros, 3-1 Kuwas, 4-1 Peterson R: St Juste (Hee) |
| 28 | 01/04/2017 | FC Utrecht | Willem II | 2-0 | 17.906 | Lindhout | 1-0 Haller, 2-0 Zivkovic |
| 28 | 02/04/2017 | Vitesse | NEC | 2-1 | 16.654 | Gözübüyük | 1-0 Van Wolfswinkel, 1-1 Kadioglu, 2-1 Van Wolfswinkel (pen) |
| 28 | 02/04/2017 | ADO Den Haag | Roda JC Kerkrade | 4-1 | 11.740 | Higler | 1-0 Becker, 2-0 El Khayati (pen), 3-0 Havenaar, 4-0 Fernandez, 4-1 El Makrini |
| 28 | 02/04/2017 | Ajax | Feyenoord | 2-1 | 51.181 | Kuipers | 1-0 Schöne, 2-0 Neres, 2-1 Kramer |
| 28 | 02/04/2017 | FC Twente | Go Ahead Eagles | 1-2 | 26.500 | Janssen | 1-0 Ünal, 1-1 Hendriks, 1-2 Ritzmaier |
| 29 | 04/04/2017 | Excelsior | FC Utrecht | 1-3 | 4.247 | Manschot | 1-0 Van Duinen, 1-1 Haller (pen) 1-2 Mattheij (e.d.), 1-3 Kerk |
| 29 | 04/04/2017 | sc Heerenveen | Sparta Rotterdam | 3-0 | 20.800 | Vd Graaf | 1-0 Van Amersfoort, 2-0 Van Aken, 3-0 Ghoochannejhad |
| 29 | 05/04/2017 | Ajax | AZ | 4-1 | 50.000 | Higler | 1-0 Traoré, 1-1 Weghorst, 2-1 Sanchez, 3-1 Schöne, 4-1 Younes |
| 29 | 05/04/2017 | Heracles Almelo | Vitesse | 0-1 | 10.711 | Bax | 0-1 Foor; R: Pröpper (Her), Diks (Vit) |
| 29 | 05/04/2017 | FC Groningen | NEC | 2-0 | 15.00 | Van Boekel | 1-0 Mahi, 2-0 Bacuna |
| 29 | 05/04/2017 | Feyenoord | Go Ahead Eagles | 8-0 | 47.500 | Kamphuis | 1-0 Toornstra, 2-0 Elia, 3-0 Kuyt, 4-0 Toornstra, 5-0 Van der Heijden, 6-0 Bottheghin, 7-0 Kramer, 8-0 Toornstra |
| 29 | 05/04/2017 | Willem II | ADO Den Haag | 1-2 | 12.800 | S. Mulder | 0-1 El Khayati, 1- Oularé, 1-2 Havenaar |
| 29 | 06/04/2017 | Roda JC Kerkrade | PEC Zwolle | 2-1 | 12.074 | Janssen | 0-1 Mokhtar, 1-1 Van Velzen, 2-1 Rosheuvel |
| 29 | 06/04/2017 | FC Twente | PSV | 2-2 | 25.000 | Gözübüyük | 1-0 Ünal, 1-1 Locadia, 1-2 Moreno, 2-2 Celina |
| 30 | 07/04/2017 | Sparta Rotterdam | Excelsior | 2-3 | 10.606 | Lindhout | 1-0 Koolwijk (e.d.), 1-1 Hasselbaink, 1-2 Elbers, 1-3 Hasselbaink, 2-3 Pusic |
| 30 | 08/04/2017 | Vitesse | sc Heerenveen | 4-2 | 21.128 | Kamphuis | 1-0 Foor, 2-0 Van Wolfswinkel, 2-1 Slagveer, 3-1 en 4-1 Van Wolfswinkel, 4-2 Larsson |
| 30 | 08/04/2017 | ADO Den Haag | FC Groningen | 4-3 | 11.348 | Manschot | 1-0 Bakker, 2-0 Malone, 3-0 Havenaar, 4-0 Malone, 4-1 Mahi, 4-2 en 4-3 Linssen |
| 30 | 08/04/2017 | NEC | Ajax | 1-5 | 12.500 | Nijhuis | 0-1 Golla (e.d.), 0-2 Neres, 0-3 Traoré, 1-3 Kadioglu, 1-4 Traoré, 1-5 Ziyech |
| 30 | 08/04/2017 | Go Ahead Eagles | Heracles Almelo | 1-4 | 9.116 | Vd Graaf | 0-1 Bruns (pen), 0-2 Armenteros, 0-3 Peterson, 1-3 Crowley, 1-4 Armenteros (pen); R: Manu (GoA) |
| 30 | 09/04/2017 | AZ | Roda JC Kerkrade | 1-1 | 14.160 | Vd Kerkhof | 1-0 Jahanbakshsh, 1-1 Werker |
| 30 | 09/04/2017 | PEC Zwolle | Feyenoord | 2-2 | 13.250 | Blom | 1-0 Menig, 2-0 Van Polen, 2-1 en 2-2 Berghuis |
| 30 | 09/04/2017 | FC Utrecht | FC Twente | 3-0 | 22.231 | Makkelie | 1-0 Kerk, 2-0 Barazite, 3-0 Zivkovic |
| 30 | 09/04/2017 | PSV | Willem II | 5-0 | 34.800 | Van Boekel | 1-0 Isimat-Mirin, 2-0 Van GInkel, 3-0 Pereiro, 4-0 Guardado, 5-0 Van Ginkel |
| 31 | 14/04/2017 | Heracles Almelo | AZ | 1-2 | 11.198 | Kuipers | 0-1 Weghorst, 0-2 Jahanbakhsh, 1-2 Kuwas |
| 31 | 15/04/2017 | Roda JC Kerkrade | Sparta Rotterdam | 3-1 | 15.028 | Gözübüyük | 1-0 en 2-0 Ajagun, 2-1 Verhaar, 3-1 Rosheuvel |
| 31 | 15/04/2017 | ADO Den Haag | PSV | 1-1 | 13.094 | Nijhuis | 0-1 Pröpper, 1-1 Havenaar |
| 31 | 15/04/2017 | Excelsior | Vitesse | 1-0 | 4.165 | Janssen | 1-0 Hasselbaink |
| 31 | 15/04/2017 | FC Twente | NEC | 3-0 | 25.100 | Blom | 1-0 Ünal, 2-0 Jensen, 3-0 Ünal |
| 31 | 16/04/2017 | Willem II | Go Ahead Eagles | 2-0 | 13.100 | Manschot | 1-0 Sol, 2-0 Schuurman |
| 31 | 16/04/2017 | Feyenoord | FC Utrecht | 2-0 | 47.500 | Higler | 1-0 Toornstra, 2-0 Elia |
| 31 | 16/04/2017 | FC Groningen | PEC Zwolle | 5-1 | 21.666 | Vd Kerkhof | 1-0 Linssen, 2-0 Mahi, 3-0 Linssen, 3-1 Brock-Madsen, 4-1 Mahi, 5-1 Hrustic |
| 31 | 16/04/2017 | Ajax | sc Heerenveen | 5-1 | 50.000 | Makkelie | 0-1 Ghoochannejhad, 1-1 Viergever, 2-1 De Ligt, 3-1 Klaassen, 4-1 Dolberg (pen), 5-1 Neres |
| 32 | 21/04/2017 | sc Heerenveen | Willem II | 1-0 | 22.113 | Bax | 1-0 Larsson |
| 32 | 22/04/2017 | NEC | Excelsior | 0-1 | 12.300 | Kuipers | 0-1 Van Duinen |
| 32 | 22/04/2017 | PEC Zwolle | Heracles Almelo | 1-2 | 13.250 | Makkelie | 0-1 en 0-2 Armenteros, 1-2 Van de Pavert |
| 32 | 22/04/2017 | AZ | FC Twente | 2-1 | 15.427 | Mulder | 0-1 Andersen, 1-1 Bijen (e.d.), 2-1 Friday R: Andersen (Twe) |
| 32 | 22/04/2017 | Go Ahead Eagles | FC Groningen | 2-3 | 9.383 | Gözübüyük | 0-1 Mahi, 1-1 Hendriks, 1-2 Drost, 2-2 Maatsen, 2-3 Mahi |
| 32 | 23/04/2017 | FC Utrecht | Roda JC Kerkrade | 1-0 | 18.876 | Kamphuis | 1-0 Labyad |
| 32 | 23/04/2017 | Sparta Rotterdam | ADO Den Haag | 0-1 | 10.606 | Higler | 0-1 El Khayati |
| 32 | 23/04/2017 | Vitesse | Feyenoord | 0-2 | 21.000 | Van Boekel | 0-1 en 0-2 Jørgensen |
| 32 | 23/04/2017 | PSV | Ajax | 1-0 | 35.000 | Blom | 1-0 Locadia |
| 33 | 07/05/2014 | Ajax | Go Ahead Eagles | 4-0 | 50.000 | Van Boekel | 1-0 Kluivert, 2-0 Dolberg, 3-0 De Jong, 4-0 Cassierra; R: Ritzmaier (GoA) |
| 33 | 07/05/2014 | Excelsior | Feyenoord | 3-0 | 4.500 | Blom | 1-0 Hasselbaink, 2-0 Elbers, 3-0 Koolwijk |
| 33 | 07/05/2014 | FC Groningen | PSV | 1-1 | 18.000 | Higler | 1-0 Mahi, 1-1 Lammers |
| 33 | 07/05/2014 | Roda JC Kerkrade | Willem II | 1-0 | 17.839 | Makkelie | 1-0 Ajagun |
| 33 | 07/05/2014 | FC Utrecht | Vitesse | 1-0 | 20.686 | Lindhout | 1-0 Janssen |
| 33 | 07/05/2014 | Heracles Almelo | ADO Den Haag | 4-0 | 11.733 | Gözübüyük | 1-0 en 2-0 Niemeijer, 3-0 Armenteros, 4-0 Bruns |
| 33 | 07/05/2014 | NEC | AZ | 2-1 | 11.500 | Kamphuis | 1-0 Von Haacke, 1-1 Jahanbakhsh, 2-1 Awoniyi R: Haps (AZ) |
| 33 | 07/05/2014 | Sparta Rotterdam | FC Twente | 1-0 | 10.101 | Janssen | 1-0 Pusic |
| 33 | 07/05/2014 | PEC Zwolle | sc Heerenveen | 2-1 | 13.250 | Nijhuis | 1-0 Holla, 2-0 Menig, 2-1 Ghoochannejhad R: Bouy (PEC) |
| 34 | 14/05/2014 | ADO Den Haag | Excelsior | 4-1 | 13.257 | S. Mulder | 1-0 Becker, 1-1 Fortes, 2-1 Havenaar, 3-1 El Khayati, 4-1 Kanon |
| 34 | 14/05/2014 | AZ | FC Utrecht | 2-3 | 12.000 | Vd Kerkhof | 0-1 Zivkovic, 0-2 Labyad, 1-2 Vd Maarel (e.d.), 1-3 Barazite, 2-3 Jahanbakshsh; R: Svensson (AZ) |
| 34 | 14/05/2014 | Feyenoord | Heracles Almelo | 3-0 | 47.500 | Higler | 1-0, 2-0 en 3-0 (pen) Kuyt, 3-1 Van Ooijen |
| 34 | 14/05/2014 | Go Ahead Eagles | Sparta Rotterdam | 1-3 | 7.000 | Kamphuis | 0-1 Pusic, 1-1 Maatsen, 1-2 Pusic, 1-3 Goodwin |
| 34 | 14/05/2014 | FC Twente | FC Groningen | 3-5 | 22.500 | Van Boekel | 0-1 Linssen, 1-1 George, 1-2 en 1-3 Idrissi, 1-4 Thesker (e.d.), 2-4 Klich (pen), 2-5 Sørloth, 3-5 Ünal |
| 34 | 14/05/2014 | sc Heerenveen | NEC | 0-2 | 18.000 | Janssen | 0-1 Groeneveld, 0-2 Awoniyi |
| 34 | 14/05/2014 | Willem II | Ajax | 1-3 | 14.500 | Gözübüyük | 0-1 Dolbers, 0-2 Sanchez, 0-3 Klaassen, 1-3 Schuurman |
| 34 | 14/05/2014 | PSV | PEC Zwolle | 4-1 | 30.000 | Manschot | 0-1 Van de Pavert, 1-1 Moreno, 2-1 Arias, 3-1 Lammers, 4-1 Ramselaar |
| 34 | 14/05/2014 | Vitesse | Roda JC Kerkrade | 3-0 | 19.876 | Nijhuis | 1-0 en 2-0 Van Wolfswinkel, 3-0 Baker R: Paulissen (Rod) |
Play-offs voor Europa League
| 1e ronde | ||||||
| 17/05/2017 | sc Heerenveen | FC Utrecht | 1-3 | 10.187 | Gözubüyük | 0-1 Amrabat, 0-2 Ayoub, 1-2 Ødegaard, 1-3 Haller |
| 17/05/2017 | FC Groningen | AZ | 1-4 | 20.610 | Nijhuis | 0-1 Jahanbakshsh, 0-2 Weghorst, 1-2 Drost, 1-3 Stengs, 1-4 Weghorst |
| 20/05/2017 | FC Utrecht | sc Heerenveen | 2-1 | 14.152 | Higler | 1-0 Leeuwin, 2-0 Zivkovic, 2-1 Ghoochannejhad (pen) |
| 20/05/2017 | AZ | FC Groningen | 4-1 | 10.413 | Gözubüyük | 1-0 Weghorst, 1-1 Linssen, 2-1 Van Overeem, 3-1 Stengs, 4-1 Van Overeem |
| 2e ronde | ||||||
| 25/05/2017 | AZ | FC Utrecht | 3-0 | 12.026 | Blom | 1-0 Van Overeem, 2-0 Ayoub (e.d.), 3-0 Weghorst |
| 18/05/2017 | FC Utrecht w.n.s. | AZ | 3-0 | 16.586 | Van Boekel | 1-0 Janssen, 2-0 Haller, 3-0 Kerk; R: Luckassen |
Play-offs voor promotie/degradatie
| 1e ronde | ||||||
| 08/05/2017 | Helmond Sport | Almere City FC | 4-2 | 2.031 | Manschot | 0-1 Salasiwa, 0-2 Ten Voorde, 1-2 Ten Den, 2-2 Braber, 3-2 Thomassen, 4-2 Edwards |
| 08/05/2017 | RKC Waalwijk | FC Emmen | 1-5 | 4.223 | Bax | 0-1 Loen, 0-2 Kallon, 0-3 Bannink, 0-4 Olijve, 0-5 Huisman, 1-5 Voskamp |
| 12/05/2017 | Almere City FC | Helmond Sport | 0-2 | 1.420 | Lindhout | 0-1 Thomassen, 0-2 Ten Den |
| 12/05/2017 | FC Emmen | RKC Waalwijk | 0-1 | 2.856 | Vd Graaf | 0-1 Voskamp; R: Van de Sande (RKC) |
| 2e ronde | ||||||
| 18/05/2017 | Helmond Sport | Roda JC Kerkrade | 0-1 | 3.431 | Vd Kerkhof | 0-1 Schahin; R: Auassar (Rod) |
| 18/05/2017 | MVV Maastricht | SC Cambuur | 1-1 | 5.642 | S. Mulder | 1-0 Nwakali, 1-1 Van de Streek |
| 18/05/2017 | FC Volendam | NAC Breda | 2-2 | 3.687 | Vd Graaf | 0-1 Agyepong, 1-1 Van Son, 2-1 Runderkamp, 2-2 Dessers |
| 18/05/2017 | FC Emmen | NEC | 1-3 | 4.969 | Lindhout | 1-0 Bannink, 1-1 Breinburg, 1-2 Grot, 1-3 Awoniyi |
| 21/05/2017 | Roda JC Kerkrade | Helmond Sport | 1-1 | 12.449 | S. Mulder | 0-1 Zeldenrust, 1-1 Van Velzen; R: Rosheuvel (Rod) |
| 21/05/2017 | SC Cambuur | MVV Maastricht | 1-2 | 9.640 | Kamphuis | 1-0 Barto, 1-1 Pereira, 1-2 Verheydt |
| 21/05/2017 | NAC Breda | FC Volendam | 2-0 | 16.554 | Janssen | 1-0 en 2-0 Dessers |
| 21/05/2017 | NEC | FC Emmen | 1-0 | 9.500 | Nijhuis | 1-0 Mayi |
| 3e ronde | ||||||
| 25/05/2017 | NAC Breda | NEC | 1-0 | 19.000 | Higler | 1-0 Dessers |
| 25/05/2017 | MVV Maastricht | Roda JC Kerkrade | 0-0 | 8.500 | Van Boekel | |
| 28/05/2017 | NEC | NAC Breda | 1-4 | 12.500 | Blom | 0-1 Dessers (pen), 1-1 Breinburg (pen), 1-2 Dessers, 1-3 Korte, 1-4 Dessers; R: Rayhi (NEC) |
| 28/05/2017 | Roda JC Kerkrade | MVV Maastricht | 1-0 | 16.019 | Janssen | 1-0 Werker; R: Kuipers (MVV) |
Roda JC Kerkrade gehandhaafd, NEC gedegradeerd, NAC Breda gepromoveerd
Topscorers
| 1 | Nicolai Jorgensen | Feyenoord | 21 |
| 2 | Ricky van Wolfswinkel | Vitesse | 20 |
| 3 | Reza Ghoochannejhad | SC Heerenveen | 19 |
| 4 | Samuel Armenteros | SC Heracles Almelo | 19 |
| 5 | Enes Ünal | FC Twente | 18 |
| 6 | Mimoun Mahi | FC Groningen | 17 |
| 7 | Kasper Dolberg | Ajax | 16 |
| 8 | Jens Toornstra | Feyenoord | 14 |
| 9 | Davy Klaassen | Ajax | 14 |
| 10 | Sebastien Haller | FC Utrecht | 13 |
Ajax en PSV zijn ver boven de rest van de Erediviseclubs verheven en maken er een zinderende ontknoping van. Met een gelijk aantal punten gaan ze de laatste speeldag in. Door een beter doelsaldo heeft Ajax de titel voor het grijpen, maar de ploeg vergaloppeert zich tegen laagvlieger De Graafschap (1-1). PSV wint wel ‘gewoon’ bij PEC Zwolle en zo krijgt Eindhoven toch nog een onverwacht kampioensfeest. Het wordt zo een prima jaar voor PSV, dat als eerste Nederlandse club sinds lange tijd weer eens overwintert in de Champioens League en pas na strafschoppen buigt tegen Atletico Madrid.
Feyenoord doet tot in december ook mee bovenin, maar kent een dramatische serie van zeven nederlagen en moet zelfs vrezen voor Europees voetbal. In de laatste fase van de competitie loopt het weer beter en uiteindelijk pakken de Rotterdammers voor het eerst in acht jaar weer eens een prijs: de KNVB Beker. AZ knokt zich na een sterke tweede seizoenhelft met een ontbolsterende Vincent Janssen naar een rechtstreeks Europees ticket. Ook groot feest is het in Almelo waar Heracles zich voor het eerst in haar bestaan plaatst voor Europees voetbal.
Onderin lijkt De Graafschap lange tijd af te stevenen op rechtstreekse degradatie, maar een na een goede eindfase halen de Doetinchemmers het zwalkende Cambuur nog in. Uiteindelijk gaat het voor De Graafschap in de nacompetitie mis ten gunste van Go Ahead Eagles. Willem II red het vege lijf wel na een tweestrijd met buurman NAC.
Een verhaal apart is opnieuw FC Twente. De schandalen uit het recente verleden blijven zich opstapelen, waardoor de KNVB de club de licentie ontneemt en terugzet naar de Eerste Divisie. Op het allerlaatste moment red de club het vege lijf, doordat de beroepscommissie FC Twente in het gelijk stelt. Eerder had de club door een goede tweede seizoenshelft handhaving op sportieve gronden al veiliggesteld.
Uitslagenmatrix
| ADO | AJA | AZ | CAM | EXC | FEY | GRA | GRO | HEE | HER | NEC | PEC | PSV | ROD | TWE | UTR | VIT | WIL | |
| ADO Den Haag | * | 0-1 | 1-2 | 2-1 | 3-3 | 1-0 | 1-1 | 0-1 | 1-1 | 0-1 | 1-0 | 0-2 | 2-2 | 2-2 | 2-1 | 1-1 | 2-2 | 1-1 |
| Ajax | 4-0 | * | 4-1 | 5-1 | 3-0 | 2-1 | 2-1 | 2-0 | 5-2 | 0-0 | 2-2 | 3-0 | 1-2 | 6-0 | 4-0 | 2-2 | 1-0 | 3-0 |
| AZ | 0-1 | 0-3 | * | 3-1 | 2-0 | 4-2 | 4-1 | 4-1 | 3-1 | 3-1 | 2-4 | 5-1 | 2-4 | 0-1 | 3-1 | 2-2 | 1-0 | 0-0 |
| SC Cambuur | 1-1 | 0-1 | 1-1 | * | 0-2 | 0-2 | 2-3 | 2-2 | 0-1 | 1-6 | 3-1 | 1-0 | 0-6 | 0-1 | 0-0 | 0-2 | 0-2 | 1-1 |
| Excelsior | 2-4 | 0-2 | 2-2 | 1-4 | * | 2-4 | 3-0 | 2-1 | 1-1 | 1-3 | 2-0 | 2-2 | 1-3 | 0-1 | 1-1 | 1-0 | 0-3 | 0-0 |
| Feyenoord | 0-2 | 1-1 | 3-1 | 3-1 | 3-0 | * | 3-1 | 1-1 | 1-2 | 3-0 | 1-0 | 2-0 | 0-2 | 1-1 | 5-0 | 3-2 | 2-0 | 1-0 |
| De Graafschap | 3-1 | 1-1 | 1-3 | 2-2 | 2-0 | 1-2 | * | 1-2 | 0-1 | 0-1 | 1-1 | 0-3 | 3-6 | 3-0 | 1-1 | 0-1 | 2-2 | 2-2 |
| FC Groningen | 2-1 | 1-2 | 2-0 | 2-0 | 2-0 | 1-1 | 3-1 | * | 3-1 | 2-1 | 0-0 | 2-0 | 0-3 | 1-0 | 1-1 | 1-4 | 0-3 | 2-1 |
| sc Heerenveen | 0-4 | 0-2 | 4-2 | 2-0 | 2-1 | 2-5 | 3-1 | 1-2 | * | 0-1 | 1-1 | 1-1 | 1-1 | 3-0 | 1-3 | 0-4 | 0-0 | 3-1 |
| Heracles Almelo | 1-1 | 0-2 | 3-6 | 3-1 | 0-0 | 2-2 | 2-1 | 2-1 | 2-0 | * | 3-0 | 2-0 | 2-1 | 0-5 | 2-0 | 1-1 | 1-1 | 2-1 |
| NEC | 4-1 | 0-2 | 0-3 | 2-1 | 1-0 | 3-1 | 2-0 | 1-1 | 2-0 | 1-0 | * | 2-2 | 0-3 | 1-2 | 2-0 | 1-0 | 2-1 | 1-0 |
| PEC Zwolle | 2-1 | 0-2 | 2-1 | 2-2 | 3-0 | 3-1 | 2-1 | 1-3 | 5-2 | 1-1 | 2-0 | * | 1-3 | 3-1 | 2-1 | 1-2 | 1-5 | 4-1 |
| PSV | 2-0 | 0-2 | 3-0 | 6-2 | 1-1 | 3-1 | 4-2 | 2-0 | 1-1 | 2-0 | 2-1 | 3-2 | * | 1-1 | 4-2 | 3-1 | 2-0 | 2-0 |
| Roda JC | 1-1 | 2-2 | 0-1 | 1-1 | 1-2 | 1-1 | 1-0 | 0-0 | 1-2 | 3-1 | 0-0 | 0-5 | 0-3 | * | 0-1 | 1-0 | 1-2 | 2-3 |
| FC Twente | 1-4 | 2-2 | 2-2 | 3-0 | 2-0 | 0-1 | 2-1 | 2-0 | 1-4 | 4-0 | 1-0 | 2-1 | 1-3 | 2-1 | * | 3-1 | 2-2 | 1-3 |
| FC Utrecht | 2-2 | 1-0 | 1-3 | 3-3 | 2-1 | 1-2 | 0-2 | 2-0 | 1-1 | 4-2 | 3-1 | 1-0 | 0-2 | 1-1 | 4-2 | * | 2-1 | 2-1 |
| Vitesse | 2-2 | 1-3 | 0-2 | 4-1 | 0-0 | 0-2 | 3-0 | 5-0 | 3-0 | 1-1 | 1-0 | 1-1 | 0-1 | 3-0 | 5-1 | 1-3 | * | 0-1 |
| Willem II | 0-2 | 0-4 | 0-2 | 3-0 | 2-3 | 0-1 | 0-0 | 1-1 | 2-2 | 0-0 | 0-1 | 0-1 | 2-2 | 3-2 | 2-3 | 3-1 | 1-1 | * |
Eindstand
| 1 | PSV * ** | 34 | 26 | 6 | 2 | 84 | 88 | 32 | 56 | 33.594 |
| 2 | Ajax ** | 34 | 25 | 7 | 2 | 82 | 81 | 21 | 60 | 44.795 |
| 3 | Feyenoord *** | 34 | 19 | 6 | 9 | 63 | 62 | 40 | 22 | 47.412 |
| 4 | AZ *** | 34 | 18 | 5 | 11 | 59 | 70 | 53 | 17 | 15.180 |
| 5 | FC Utrecht + | 34 | 15 | 8 | 11 | 53 | 57 | 48 | 9 | 17.312 |
| 6 | Heracles Almelo + *** | 34 | 14 | 9 | 11 | 51 | 47 | 49 | -2 | 11.243 |
| 7 | FC Groningen + | 34 | 14 | 8 | 12 | 50 | 41 | 48 | -7 | 19.408 |
| 8 | PEC Zwolle + | 34 | 14 | 6 | 14 | 48 | 56 | 54 | 2 | 12.238 |
| 9 | Vitesse | 34 | 12 | 10 | 12 | 46 | 55 | 38 | 17 | 16.872 |
| 10 | NEC | 34 | 13 | 7 | 14 | 46 | 37 | 42 | -5 | 11.661 |
| 11 | ADO Den Haag | 34 | 10 | 13 | 11 | 43 | 48 | 49 | -1 | 12.028 |
| 12 | sc Heerenveen | 34 | 11 | 9 | 14 | 42 | 46 | 61 | -15 | 23.581 |
| 13 | FC Twente ¹ | 34 | 12 | 7 | 15 | 40 | 49 | 64 | -15 | 25.223 |
| 14 | Roda JC Kerkrade | 34 | 8 | 10 | 16 | 34 | 34 | 55 | -21 | 14.812 |
| 15 | Excelsior | 34 | 7 | 9 | 18 | 30 | 34 | 60 | -26 | 3.533 |
| 16 | Willem II ^^^ | 34 | 6 | 11 | 17 | 29 | 35 | 53 | -18 | 12.702 |
| 17 | De Graafschap ^^ | 34 | 5 | 8 | 21 | 23 | 39 | 66 | -27 | 10.048 |
| 18 | SC Cambuur ^ | 34 | 3 | 9 | 22 | 18 | 33 | 79 | -46 | 9.699 |
FC Twente 3 punten in mindering
Wedstrijden
| R | Datum | Thuis | Uit | Sc: | Ts: | Ar: | Details: |
|---|---|---|---|---|---|---|---|
| 1 | 08/08/2015 | Roda JC Kerkrade | Heracles Almelo | 3-1 | 13.472 | Janssen | 0-1 Bel Hassani, 1-1 Gyasi, 2-1 Van Hyfte, 3-1 Faik |
| 1 | 08/08/2015 | Feyenoord | FC Utrecht | 3-2 | 47.500 | Blom | 1-0 Kazim, 1-1 Haller, 2-1 Vilhena, 3-1 Kuyt (pen), 3-2 Haller (pen); R: Karsdorp (Fey) |
| 1 | 09/08/2015 | AZ | Ajax | 0-3 | 16.673 | Kuipers | 0-1 en 0-2 El Ghazi, 0-3 Gudelj |
| 1 | 09/08/2015 | Willem II | Vitesse | 1-1 | 11.000 | Kamphuis | 1-0 Falkenburg, 1-1 Olijnyk; R: Olijnik (Vit) |
| 1 | 11/08/2015 | sc Heerenveen | De Graafschap | 3-1 | 22.000 | Vd Graaf | 1-0 Thern, 2-0 Te Vrede, 3-0 Thern, 3-1 Vermeij |
| 1 | 11/08/2015 | ADO Den Haag | PSV | 2-2 | 13.125 | Liesveld | 0-1 Maher, 1-1 Alberg, 1-2 De Jong, 2-2 Hansen |
| 1 | 12/08/2015 | FC Groningen | FC Twente | 1-1 | 20.000 | Janssen | 0-1 Tapia, 1-1 De Leeuw |
| 1 | 12/08/2015 | PEC Zwolle | SC Cambuur | 2-2 | 11.650 | Higler | 1-0 Marcellis, 2-0 Becker, 2-1 Bakker, 2-2 Overgoor |
| 1 | 12/08/2015 | NEC | Excelsior | 1-0 | 10.240 | Manschot | 1-0 Foor |
| 2 | 14/08/2015 | Vitesse | Roda JC Kerkrade | 3-0 | 11.000 | Braamhaar | 1-0 Baker (pen), 2-0 Dauda, 3-0 Nathan R: Van Peppen (Rod) |
| 2 | 15/08/2015 | De Graafschap | PEC Zwolle | 0-3 | 8.100 | Lindhout | 0-1 Marinus, 0-2 Van Hintum, 0-3 Becker |
| 2 | 15/08/2015 | Ajax | Willem II | 3-0 | 45.000 | Nijhuis | 1-0 Milik, 2-0 en 3-0 El Ghazi |
| 2 | 15/08/2015 | FC Twente | ADO Den Haag | 1-4 | 22.000 | Gözübüyük | 0-1 Havenaar, 0-2 Schaken, 1-2 Ziyech, 1-3 Wormgoor, 1-4 Duplan |
| 2 | 15/08/2015 | Excelsior | AZ | 2-2 | 3.000 | Vd Kerkhof | 1-0 Stans, 1-1 Henriksen, 2-1 Van Weert, 2-2 Mühren |
| 2 | 16/08/2015 | PSV | FC Groningen | 2-0 | 32.000 | Makkelie | 1-0 en 2-0 Narsingh |
| 2 | 16/08/2015 | SC Cambuur | Feyenoord | 0-2 | 10.000 | Van Boekel | 0-1 Kramer, 0-2 Kuyt (pen) |
| 2 | 16/08/2015 | FC Utrecht | sc Heerenveen | 1-1 | 16.364 | Kuipers | 1-0 Haller (pen), 1-1 Slagveer |
| 2 | 16/08/2015 | Heracles Almelo | NEC | 3-0 | 12.084 | Kamphuis | 1-0 Tannane, 2-0 Bruns, 3-0 Weghorst R: Appiah (NEC) |
| 3 | 21/08/2015 | FC Groningen | Excelsior | 2-0 | 19.277 | Van de Graaf | 1-0 en 2-0 Mahi |
| 3 | 22/08/2015 | Roda JC Kerkrade | De Graafschap | 1-0 | 13.130 | Nijhuis | 1-0 Van Hyfte |
| 3 | 22/08/2015 | sc Heerenveen | PSV | 1-1 | 24.645 | Braamhaar | 1-0 Cavlan (pen), 1-1 De Jong |
| 3 | 23/08/2015 | NEC | Ajax | 1-1 | 12.321 | Higler | 0-1 Milik, 0-2 Van Eijden (e.d.) |
| 3 | 22/08/2015 | SC Cambuur | Heracles Almelo | 1-6 | 9.630 | Liesveld | 0-1, 0-2 (pen), 0-3 en 0-4 Tannane, 0-5 Weghorst, 1-5 Ogbeche, 1-6 Bruns |
| 3 | 23/08/2015 | PEC Zwolle | FC Twente | 2-1 | 12.123 | Blom | 1-0 Veldwijk (pen), 1-1 Ziyech, 2-1 Rienstra |
| 3 | 23/08/2015 | AZ | Willem II | 0-0 | 14.144 | Janssen | |
| 3 | 23/08/2015 | ADO Den Haag | FC Utrecht | 1-1 | 12.293 | Van Boekel | 0-1 Heller (pen), 1-1 Havenaar |
| 3 | 23/08/2015 | Feyenoord | Vitesse | 2-0 | 47.500 | Gözübüyük | 1-0 Kuyt (pen), 2-0 Basacikoglu |
| 4 | 28/08/2015 | Willem II | NEC | 0-1 | 12.000 | Vd Kerkhof | 0-1 Foor |
| 4 | 29/08/2015 | FC Utrecht | FC Groningen | 2-0 | 14.705 | Liesveld | 1-0 Ramselaar, 2-0 Letschert |
| 4 | 29/08/2015 | sc Heerenveen | PEC Zwolle | 1-1 | 22.763 | Van Boekel | 1-0 Larsson, 1-1 Veldwijk |
| 4 | 29/08/2015 | Excelsior | De Graafschap | 3-0 | 3.400 | Kamphuis | 1-0 Fischer, 2-0 Kuwas, 3-0 Van Mieghem |
| 4 | 29/08/2015 | Heracles Almelo | FC Twente | 2-0 | 12.100 | Higler | 1-0 Bel Hassani, 2-0 Weghorst |
| 4 | 30/08/2015 | Ajax | ADO Den Haag | 4-0 | 43.578 | Makkelie | 1-0 El Ghazi, 2-0 Klassen, 3-0 Veltman, 4-0 El Ghazi |
| 4 | 30/08/2015 | AZ | Roda JC Kerkrade | 0-1 | 14.226 | Manschot | 0-1 Griffiths |
| 4 | 30/08/2015 | Vitesse | SC Cambuur | 4-1 | 13.573 | Lindhout | 1-0 Baker (pen), 1-1 Van der Streek, 2-1 Dauda, 3-1 Kashia, 4-1 Solanke |
| 4 | 30/08/2015 | PSV | Feyenoord | 3-1 | 35.000 | Kuipers | 0-1 Bruma (e.d.), 1-1 Lestienne, 2-1 Arias, 3-1 Locadia (pen) |
| 5 | 12/09/2015 | De Graafschap | AZ | 1-3 | 8.564 | Higler | 0-1 Brezancic, 1-1 Will, 1-2 en 1-3 Henriksen |
| 5 | 12/09/2015 | Roda JC Kerkrade | NEC | 0-0 | 13.967 | Kuipers | |
| 5 | 12/09/2015 | FC Twente | Ajax | 2-2 | 29.000 | Van Boekel | 1-0 Gutierrez, 2-0 Ziyech (pen), 2-1 Fischer, 2-2 Gudelj (pen) |
| 5 | 12/09/2015 | SC Cambuur | PSV | 0-6 | 9.821 | Blom | 0-1 (pen), 0-2 en 0-3 De Jong, 0-4 Pröpper, 0-5 en 0-6 Locadia; R: Van de Streek (Cam) |
| 5 | 12/09/2015 | PEC Zwolle | Excelsior | 3-0 | 11.800 | Makkelie | 1-0, 2-0 en 3-0 Veldwijk R: Fischer, Van Weert (Exc) |
| 5 | 13/09/2015 | FC Groningen | sc Heerenveen | 3-1 | 21.101 | Gözübüyük | 1-0 Hoesen, 2-0 Linssen, 2-1 Thern, 3-1 Mahi |
| 5 | 13/09/2015 | Feyenoord | Willem II | 1-0 | 47.500 | Liesveld | 1-0 Elia |
| 5 | 13/09/2015 | ADO Den Haag | Heracles Almelo | 0-1 | 10.071 | Manschot | 0-1 Weghorst |
| 5 | 13/09/2015 | FC Utrecht | Vitesse | 2-1 | 16.056 | Nijhuis | 1-0 Janssen, 1-1 Kashia, 2-1 Ramselaar |
| 6 | 07/07/1900 | NEC | sc Heerenveen | 2-0 | 10.118 | Lindhout | 1-0 en 2-0 Santos |
| 6 | 17/07/1900 | sc Cambuur | FC Twente | 0-0 | 9.714 | Kamphuis | |
| 6 | 19/09/2015 | PEC Zwolle | ADO Den Haag | 2-1 | 12.150 | Janssen | 0-1 Havenaar, 1-1 Becker, 2-1 Veldwijk |
| 6 | 19/09/2015 | Heracles Almelo | PSV | 2-1 | 12.034 | Gözübüyük | 0-1 De Jong, 1-1 Fledderus, 2-1 Bruns |
| 6 | 19/09/2015 | Willem II | FC Utrecht | 3-1 | 11.600 | Mulder | 1-0 Falkenburg, 1-1 Barazite, 2-1 Nganioni, 3-1 Haemhouts; R: Haller (Utr) |
| 6 | 20/09/2015 | Roda JC Kerkrade | Feyenoord | 1-1 | 17.142 | Van Boekel | 0-1 Kramer, 1-1 Faik |
| 6 | 20/09/2015 | Excelsior | Ajax | 0-2 | 3.541 | Blom | 0-1 El Ghazi, 0-2 Milik |
| 6 | 20/09/2015 | Vitesse | De Graafschap | 3-0 | 15.139 | Vd Kerkhof | 1-0 Kashia, 2-0 Qazaishvili, 3-0 Rashica |
| 6 | 20/09/2015 | FC Groningen | AZ | 2-0 | 18.000 | Nijhuis | 1-0 Linssen, 2-0 Mahi |
| 7 | 26/09/2015 | sc Heerenveen | Vitesse | 0-0 | 23.984 | Higler | |
| 7 | 26/09/2015 | FC Utrecht | SC Cambuur | 3-3 | 16.073 | Vd Graaf | 0-1 en 0-2 Ogbeche, 1-2 Janssen, 2-2 Barazite, 2-3 Van de Streek, 3-3 Janssen (pen) R: Zeinstra (Cam) |
| 7 | 26/09/2015 | Ajax | FC Groningen | 2-0 | 45.676 | Liesveld | 1-0 Gudelj, 2-0 Fischer |
| 7 | 26/09/2015 | AZ | Heracles Almelo | 3-1 | 13.121 | Van Boekel | 1-0 Henriksen, 2-0 Gouweleeuw, 2-1 Navratil, 3-1 Tankovic |
| 7 | 26/09/2015 | PSV | NEC | 2-1 | 32.500 | Makkelie | 1-0 De Jong, 1-1 Santos (pen), 2-1 Locadia |
| 7 | 27/09/2015 | De Graafschap | Willem II | 2-2 | 9.183 | Janssen | 0-1 en 0-2 Falkenburg, 1-1 Peters (pen), 2-1 Vermeij; R: Bannink (Gra) |
| 7 | 27/09/2015 | Feyenoord | PEC Zwolle | 2-0 | 47.500 | Kuipers | 1-0 Kuijt, 2-0 Elia |
| 7 | 27/09/2015 | ADO Den Haag | Excelsior | 3-3 | 10.667 | Mulder | 1-0 Havenaar, 1-1 Auassar, 2-1 Zuiverloon, 2-2 Auassar, 3-2 Havenaar, 3-3 Kuwas |
| 7 | 27/09/2015 | FC Twente | Roda JC Kerkrade | 2-1 | 24.700 | Gözübüyük | 1-0 Oosterwijk, 2-0 Mokotjo, 2-1 Juric |
| 8 | 02/10/2015 | Heracles Almelo | sc Heerenveen | 2-0 | 10.780 | Vd Kerkhof | 1-0 Bel Hassani, 2-0 Weghorst |
| 8 | 03/10/2015 | NEC | ADO Den Haag | 4-1 | 11.534 | Blom | 1-0 Meijers (e.d.), 1-1 Wormgoor, 2-1 Santos, 3-1 Limbombe, 4-1 Santos |
| 8 | 03/10/2015 | Roda JC Kerkrade | SC Cambuur | 1-1 | 14.489 | Manschot | 0-1 Ogbeche, 1-1 Van Hyfte |
| 8 | 03/10/2015 | Willem II | PEC Zwolle | 0-1 | 11.500 | Liesveld | 0-1 Bouy |
| 8 | 03/10/2015 | Excelsior | FC Utrecht | 1-0 | 3.430 | Lindhout | 1-0 Stans (pen) |
| 8 | 04/10/2015 | De Graafschap | Feyenoord | 1-2 | 12.145 | Makkelie | 1-0 Van Beek (e.d.), 1-1 Kramer, 1-2 Elia |
| 8 | 04/10/2015 | Ajax | PSV | 1-2 | 51.154 | Nijhuis | 0-1 Pereiro, 1-1 Younes, 1-2 Pereiro |
| 8 | 04/10/2015 | Vitesse | FC Groningen | 5-0 | 16.185 | Kuipers | 1-0 Solanke, 2-0 Diks, 3-0 Qazaishvili, 4-0 Nathan, 5-0 Dauda |
| 8 | 04/10/2015 | AZ | FC Twente | 3-1 | 13.000 | Janssen | 1-0 en 2-0 Janssen, 3-0 Hupperts, 3-0 Ziyech |
| 9 | 17/10/2015 | SC Cambuur | AZ | 1-1 | 9.666 | Mulder | 0-1 Janssen, 1-1 Ogbeche; R: Dammers (Cam) |
| 9 | 17/10/2015 | FC Groningen | Willem II | 2-1 | 19.000 | Higler | 1-0 Mahi, 1-1 Reijnen (e.d.), 2-1 Hoesen |
| 9 | 17/10/2015 | Heracles Almelo | Ajax | 0-2 | 12.080 | Blom | 0-1 El Ghazi, 0-2 Gudelj |
| 9 | 17/10/2015 | FC Utrecht | Roda JC Kerkrade | 1-1 | 15.779 | Nijhuis | 1-0 Haller, 1-1 Juric |
| 9 | 17/10/2015 | PSV | Excelsior | 1-1 | 32.800 | Kamphuis | 1-0 Pröpper, 1-1 Hasselbaink |
| 9 | 18/10/2015 | FC Twente | NEC | 1-0 | 22.000 | Manschot | 1-0 Bijen |
| 9 | 18/10/2015 | sc Heerenveen | Feyenoord | 2-5 | 25.350 | Gözübüyük | 0-1 Kuyt, 0-2 Kramer, 0-3 Gustafson, 0-4 en 0-5 Kuyt, 1-5 en 2-5 Veerman |
| 9 | 18/10/2015 | ADO Den Haag | De Graafschap | 1-1 | 10.512 | Kuipers | 1-0 Havenaar, 1-1 Zuiverloon (pen) |
| 9 | 18/10/2015 | PEC Zwolle | Vitesse | 1-5 | 12.250 | Van Boekel | 0-1 Baker, 1-1 Lam, 1-2 Solanke (pen), 1-3 Qazaishvili, 1-4 Oliynik (pen), 1-5 Rashica R: Bouy (PEC) |
| 10 | 23/10/2015 | PEC Zwolle | FC Utrecht | 1-2 | 12.300 | Braamhaar | 1-0 Marinus, 1-1 en 1-2 (pen) Haller R: Van de Maarel (Utr) |
| 10 | 24/10/2015 | Willem II | sc Heerenveen | 2-2 | 13.500 | Manschot | 1-0 Zivkovic, 1-1 veerman, 2-1 Andersen, 2-2 Slagveer |
| 10 | 24/10/2015 | De Graafschap | Heracles Almelo | 0-1 | 10.362 | Kamphuis | 0-1 Bel Hassani |
| 10 | 24/10/2015 | FC Twente | PSV | 1-3 | 25.500 | Blom | 0-1 De Jong, 1-1 Ziyech, 1-2 Locadia, 1-3 Pereiro |
| 10 | 24/10/2015 | Roda JC Kerkrade | Excelsior | 1-2 | 13.769 | Vd kerkhof | 1-0 Juric, 1-1 Fischer, 1-2 Stans |
| 10 | 25/10/2015 | SC Cambuur | ADO Den Haag | 1-1 | 9.519 | Higler | 0-1 Havenaar, 1-1 Narsingh |
| 10 | 25/10/2015 | Vitesse | Ajax | 1-3 | 21.163 | Liesveld | 1-0 Qazaishvili, 1-1 Fischer, 1-2 Bazoer, 1-3 Schöne |
| 10 | 25/10/2015 | NEC | FC Groningen | 1-1 | 11.630 | Janssen | 0-1 Rusnak, 1-1 Santos |
| 10 | 25/10/2015 | Feyenoord | AZ | 3-1 | 47.500 | Kuipers | 1-0 Kuyt, 1-1 Van Overeem, 2-1 en 3-1 (pen) Kuyt |
| 11 | 30/10/2015 | Heracles Almelo | Willem II | 2-1 | 11.123 | Janssen | 1-0 Navratil, 2-0 Zomer, 2-1 Falkenburg |
| 11 | 31/10/2015 | FC Groningen | PEC Zwolle | 2-0 | 20.000 | Manschot | 1-0 De Leeuw, 2-0 Burnet |
| 11 | 31/10/2015 | Ajax | Roda JC Kerkrade | 6-0 | 50.000 | Kuipers | 1-0 Fischer, 2-0 Milik, 3-0 Klaassen, 4-0 Fischer, 5-0 Milik, 6-0 Klaassen, |
| 11 | 31/10/2015 | Excelsior | Vitesse | 0-3 | 3.600 | Gözübüyük | 0-1 Solanke (pen), 0-2 Diks, 0-3 Rahsica |
| 11 | 31/10/2015 | De Graafschap | PSV | 3-6 | 11.163 | Nijhuis | 0-1 Pröpper, 0-2 Guardado, 0-3 Pröpper, 1-3 Driver, 2-3 Bannink, 3-3 Kabasele, 3-4 De Jong, 3-5 Narsingh, 3-6 Pereiro |
| 11 | 01/11/2015 | ADO Den Haag | Feyenoord | 1-0 | 14.261 | Blom | 1-0 Van Beek (e.d.); R: Duplan (ADO) |
| 11 | 01/11/2015 | sc Heerenveen | SC Cambuur | 2-0 | 26.100 | Liesveld | 1-0 Dammers (e.d.), 2-0 te Vrede (pen) |
| 11 | 01/11/2015 | FC Utrecht | FC Twente | 4-2 | 17.034 | Higler | 0-1 Agyepong, 1-1 Letschert, 2-1 Drommel (e.d.), 2-2 Ziyech, 3-2 Barazite, 4-2 Haller (pen.) |
| 11 | 01/11/2015 | AZ | NEC | 2-4 | 15.555 | Vd Kerkhof | 0-1 Limbombe, 1-1 Henriksen, 1-2 Santos, 1-3 Woudenberg, 1-4 Limbombe, 2-3 Henriksen |
| 12 | 06/11/2015 | Roda JC Kerkrade | ADO Den Haag | 1-1 | 14.182 | Braamhaar | 1-0 Van Hyfte, 1-1 Havenaar; R: Juric (Rod) |
| 12 | 07/11/2015 | FC Twente | sc Heerenveen | 1-4 | 25.600 | Kamphuis | 0-1 Slagveer, 0-2 Otigba, 1-2 Ziyech, 1-3 Andersen (e.d.), 1-4 Larsson |
| 12 | 07/11/2015 | NEC | De Graafschap | 2-0 | 11.673 | Liesveld | 1-0 (pen) en 2-0 Santos |
| 12 | 07/11/2015 | Willem II | Excelsior | 2-3 | 11.200 | Van Boekel | 1-0 Zivkovic, 1-1 Van Weert, 2-1 Dries Wuytens, 2-2 Stans (pen), 2-3 Van Mieghem |
| 12 | 07/11/2015 | PEC Zwolle | Heracles Almelo | 1-1 | 12.420 | Higler | 0-1 Weghorst, 1-1 Nijland |
| 12 | 08/11/2015 | PSV | FC Utrecht | 3-1 | 34.100 | Kuipers | 1-0 Moreno, 1-1 Ramselaar, 2-1 Arias, 3-1 De Jong |
| 12 | 08/11/2015 | SC Cambuur | FC Groningen | 2-2 | 9.813 | Gözübüyük | 1-0 en 2-0 Barto, 2-1 Kappelhof, 2-2 Drost |
| 12 | 08/11/2015 | Feyenoord | Ajax | 1-1 | 47.500 | Nijhuis | 1-0 Van Beek, 1-1 Klaassen |
| 12 | 08/11/2015 | Vitesse | AZ | 0-2 | 17.000 | Janssen | 0-1 Janssen, 0-2 Henriksen; R: Nakamba |
| 13 | 21/11/2015 | AZ | sc Heerenveen | 3-1 | 15.521 | Lindhout | 0-1 Te Vrede, 1-1 Janssen, 2-1 El Hamdaoui, 3-1 Janssen |
| 13 | 21/11/2015 | Roda JC Kerkrade | PEC Zwolle | 0-5 | 14.378 | Makkelie | 0-1 Marinus, 0-2 (pen) en 0-3 Thomas, 0-4 Veldwijk, 0-5 Nijland |
| 13 | 21/11/2015 | Ajax | SC Cambuur | 5-1 | 20.000 | Janssen | 1-0 Veltman, 1-1 Van de Streek, 2-1 Milik, 3-1 en 4-1 Klaassen, 5-1 Younes |
| 13 | 21/11/2015 | Willem II | PSV | 2-2 | 14.112 | Gözübüyük | 0-1 Pereiro, 1-1 en 2-1 Falkenburg, 2-2 De Jong |
| 13 | 21/11/2015 | De Graafschap | FC Groningen | 1-2 | 10.083 | Vd Graaf | 0-1 Rusnak, 0-2 De Leeuw, 1-2 Kabasele (pen) |
| 13 | 22/11/2015 | Heracles Almelo | Excelsior | 0-0 | 11.000 | S. Mulder | |
| 13 | 22/11/2015 | Feyenoord | FC Twente | 5-0 | 47.500 | Liesveld | 1-0 en 2-0 Gustafsson, 3-0 Kramer, 4-0 El Ahmadi, 5-0 Basacikoglu; R: Hölscher (Twe) |
| 13 | 22/11/2015 | NEC | FC Utrecht | 1-0 | 11.509 | Van Boekel | 1-0 Santos (pen) |
| 13 | 22/11/2015 | ADO Den Haag | Vitesse | 2-2 | 12.133 | Nijhuis | 0-1 Yeini, 1-1 Schaken, 1-2 Leerdam, 2-2 Derijck (pen) |
| 14 | 27/11/2015 | SC Cambuur | De Graafschap | 2-3 | 10.000 | Makkelie | 0-1 Peters, 0-2 Straalman, 1-2 Overgoor, 2-2 Will (e.d.), 2-3 Tarfi; R: Pröpper (Gra) |
| 14 | 28/11/2015 | sc Heerenveen | Roda JC Kerkrade | 3-0 | 22.850 | Van Boekel | 1-0 Te Vrede, 2-0 Slagveer, 3-0 Te Vrede (pen) |
| 14 | 28/11/2015 | Excelsior | Feyenoord | 2-4 | 3.750 | Braamhaar | 0-1 Kuyt, 0-2 Kramer, 1-2 Van Mieghem, 1-3 en 1-4 Kramer, 2-4 Van Weert |
| 14 | 28/11/2015 | FC Twente | Willem II | 1-3 | 24.100 | Manschot | 0-1 en 0-2 Andersen, 1-2 Oosterwijk, 1-3 Andersen |
| 14 | 29/11/2015 | Vitesse | NEC | 1-0 | 19.212 | Kuipers | 1-0 Qazaishvili |
| 14 | 29/11/2015 | PEC Zwolle | Ajax | 0-2 | 12.500 | Blom | 0-1 Younes, 0-2 Serero |
| 14 | 29/11/2015 | FC Groningen | ADO Den Haag | 2-1` | 19.480 | Higler | 0-1 Duplan, 1-1 Beugelsdijk (e.d.), 2-1 Hoesen |
| 14 | 29/11/2015 | FC Utrecht | Heracles Almelo | 4-2 | 18.144 | Kamphuis | 0-1 Bel Hassani, 1-1 en 2-1 Barazite, 2-2 Tannane, 3-2 en 4-2 Haller; R: Conboy (Utr) |
| 14 | 29/11/2015 | PSV | AZ | 3-0 | 33.000 | Liesveld | 1-0 Luckassen (e.d.), 2-0 en 3-0 De Jong R: Luckassen (AZ) |
| 15 | 04/12/2015 | AZ | ADO Den Haag | 0-1 | 13.743 | Kuipers | 0-1 Bakker |
| 15 | 05/12/2015 | Excelsior | FC Twente | 1-1 | 3.400 | Vd Kerkhof | 1-0 Van Weert, 1-1 Ziyech |
| 15 | 05/12/2015 | De Graafschap | FC Utrecht | 0-1 | 10.175 | Mulder | 0-1 Strieder; R: Van der Maarel (Utr) |
| 15 | 05/12/2015 | Vitesse | PSV | 0-1 | 16.879 | Blom | 0-1 Hendrix |
| 15 | 05/12/2015 | Ajax | sc Heerenveen | 5-2 | 40.000 | Makkelie | 1-0 Fischer, 2-0 Milik, 3-0 Younes, 3-1 Te Vrede, 4-1 Fischer, 5-1 Klaassen, 5-2 Te Vrede |
| 15 | 06/12/2015 | Willem II | SC Cambuur | 3-0 | 12.050 | Higler | 1-0 Joppen, 2-0 Falkenburg, 3-0 S. Wuytens |
| 15 | 06/12/2015 | Feyenoord | Heracles Almelo | 3-0 | 47.500 | Nijhuis | 1-0 Elia, 2-0 Kuyt, 3-0 Kramer: R: Zomer (Her) |
| 15 | 06/12/2015 | NEC | PEC Zwolle | 2-2 | 10.503 | Gözübüyük | 0-1 Sainsbury, 0-2 Veldwijk, 1-2 Bikel, 2-2 Limbombe |
| 15 | 06/12/2015 | Roda JC Kerkrade | FC Groningen | 0-0 | 13.171 | Janssen | |
| 16 | 11/12/2015 | sc Heerenveen | Excelsior | 2-1 | 22.150 | Vd Graaf | 1-0 Otigba, 2-0 Larsson, 2-1 Stans (pen) |
| 16 | 12/12/2015 | ADO Den Haag | Willem II | 1-1 | 11.703 | Lindhout | 1-0 Jansen, 1-1 Van der Velden (pen) R: Malone (ADO) |
| 16 | 12/12/2015 | SC Cambuur | NEC | 3-1 | 9.718 | Manschot | 1-0 Ogbeche, 1-1 Houtkoop (e.d.), 2-1 Ogbeche, 3-1 Santos (e.d.) |
| 16 | 12/12/2015 | PSV | Roda JC Kerkrade | 1-1 | 33.700 | Braamhaar | 0-1 Brenet (e.d.), 1-1 Pröpper |
| 16 | 12/12/2015 | FC Twente | De Graafschap | 2-1 | 22.500 | Janssen | 0-1 Driver, 1-1 Andersen, 2-1 Ziyech R: Marsman (Twe) |
| 16 | 13/12/2015 | FC Utrecht | Ajax | 1-0 | 14.100 | Gözübüyük | 1-0 Ayoub |
| 16 | 13/12/2015 | PEC Zwolle | AZ | 2-1 | 12.120 | Kamphuis | 1-0 Menig, 2-0 Ehihizibue, 2-1 Tankovic |
| 16 | 13/12/2015 | FC Groningen | Feyenoord | 1-1 | 22.091 | Van Boekel | 1-0 De Leeuw, 1-1 Kut; R: Van der Heijden (Fey) |
| 16 | 13/12/2015 | Heracles Almelo | Vitesse | 1-1 | 10.821 | Liesveld | 1-0 Tannane, 1-1 Rashica |
| 17 | 18/12/2015 | Vitesse | FC Twente | 5-1 | 15.987 | Gözübüyük | 1-0 Qazaishvili, 2-0 Rashica, 2-1 Ziyech, 3-1 Solanke, 4-1 Rashica, 5-1 Olijnyk |
| 17 | 19/12/2015 | Willem II | Roda JC Kerkrade | 3-2 | 13.000 | Mulder | 0-1 Juric (pen), 1-1 en 2-1 D. Wuytens, 3-1 Van der Velden, 3-2 Griffiths |
| 17 | 19/12/2015 | AZ | FC Utrecht | 2-2 | 15.765 | Nijhuis | 1-0 Johansson, 1-1 Boymans, 1-2 Haller, 2-2 Gouweleeuw (pen) |
| 17 | 19/12/2015 | Heracles Almelo | FC Groningen | 2-1 | 10.622 | Makkelie | 0-1 Linssen, 1-1 Gladon, 2-1 Bosz |
| 17 | 20/12/2015 | Excelsior | SC Cambuur | 1-4 | 3.750 | Van Boekel | 0-1 en 0-2 Ogbeche, 0-3 Byrne, 0-4 Monteiro, 1-4 Vermeulen |
| 17 | 20/12/2015 | sc Heerenveen | ADO Den Haag | 0-4 | 23.121 | Manschot | 0-1 Meijers, 0-2 Bakker, 0-3 Beugelsdijk, 0-4 Jansen |
| 17 | 20/12/2015 | PSV | PEC Zwolle | 3-2 | 34.000 | Higler | 1-0 en 2-0 Pereiro, 2-1 Van Polen (pen), 2-2 Veldwijk, 3-2 De Jong |
| 17 | 20/12/2015 | NEC | Feyenoord | 3-1 | 12.500 | Braamhaar | 0-1 Vilhena, 1-1 Bikel, 2-1 Limbombe, 3-1 Santos |
| 17 | 20/12/2015 | Ajax | De Graafschap | 2-1 | 40.000 | Liesveld | 1-0 Milik, 1-1 Vida, 2-1 Bazoer |
| 18 | 15/01/2016 | FC Twente | Heracles Almelo | 4-0 | 28.900 | Blom | 1-0 Ede, 2-0 Ziyech, 3-0 Ede, 4-0 Ter Avest |
| 18 | 16/01/2016 | SC Cambuur | Vitesse | 0-2 | 9.508 | Braamhaar | 0-1 Rashica, 0-2 Qazaishvili |
| 18 | 16/01/2016 | PEC Zwolle | sc Heerenveen | 5-2 | 12.320 | Vd Kerkhof | 1-0 Marcellis, 2-0 Van Polen, 2-1 Te Vrede, 3-1 Van Polen (pen), 4-1 Brama, 4-2 St Juste, 5-2 Nijland; R: Van den Berg (Hee) |
| 18 | 16/01/2016 | Roda JC Kerkrade | AZ | 0-1 | 13.615 | Lindhout | 0-1 Janssen; R: Luckassen (AZ) |
| 18 | 16/01/2016 | De Graafschap | Excelsior | 2-0 | 10.253 | Higler | 1-0 Peters, 2-0 Vermeij |
| 18 | 17/01/2016 | ADO Den Haag | Ajax | 0-1 | 14.561 | Van Boekel | 0-1 Younes |
| 18 | 17/01/2016 | Feyenoord | PSV | 0-2 | 47.500 | Makkelie | 0-1 Moreno, 0-2 Narsingh |
| 18 | 17/01/2016 | FC Groningen | FC Utrecht | 1-4 | 20.000 | Kuipers | 0-1 Ramselaar, 1-1 Sorloth, 1-2 Letschert, 1-3 Kum, 1-4 Ludwig; R: Ludwig (Utr) |
| 18 | 17/01/2016 | NEC | Willem II | 1-0 | 11.682 | Kamphuis | 1-0 Santos; R: Van der Struijk (Wil) |
| 19 | 22/01/2016 | FC Groningen | NEC | 0-0 | 12.000 | Nijhuis | |
| 19 | 23/01/2016 | Heracles Almelo | De Graafschap | 2-1 | 10.451 | S. Mulder | 1-0 Darri, 2-0 Bruns, 2-1 Driver |
| 19 | 23/01/2016 | Ajax | Vitesse | 1-0 | 42.000 | Kuipers | 1-0 Bazoer |
| 19 | 23/01/2016 | Excelsior | Roda JC Kerkrade | 0-1 | 3.500 | Janssen | 0-1 Faik |
| 19 | 23/01/2016 | sc Heerenveen | Willem II | 3-1 | 22.150 | Makkelie | 0-1 Van der Velden (pen), 1-1 Zeneli, 2-1 Otigba, 3-1 Larsson |
| 19 | 24/01/2016 | AZ | Feyenoord | 4-2 | 15.725 | Liesveld | 0-1 Kramer, 1-1 Henriksen, 2-1, 3-1 en 4-1 Janssen, 4-2 Vilhena |
| 19 | 24/01/2016 | FC Utrecht | PEC Zwolle | 1-0 | 21.715 | Blom | 1--0 Boymans |
| 19 | 24/01/2016 | PSV | FC Twente | 4-2 | 33.000 | Van Boekel | 0-1 Oosterwijk, 1-1 en 2-1 Moreno, 3-1 Narsingh, 3-2 Ede, 4-2 Jozefzoon |
| 19 | 24/01/2016 | ADO Den Haag | SC Cambuur | 2-1 | 10.342 | Gözübüyük | 0-1 Van de Streek, 1-1 en 2-1 Kanon |
| 20 | 26/01/2016 | Willem II | FC Groningen | 1-1 | 12.000 | Lindhout | 1-0 Wuytens, 1-1 Maduro |
| 20 | 26/01/2016 | Ajax | Heracles Almelo | 0-0 | 44.517 | Higler | |
| 20 | 27/01/2016 | AZ | SC Cambuur | 3-1 | 14.017 | Manschot | 1-0 Janssen, 2-0 Van Overeem, 3-0 Janssen, 3-1 Barto |
| 20 | 27/01/2016 | NEC | FC Twente | 2-0 | 10.958 | Vd Graaf | 1-0 Limbombe, 2-0 Santos |
| 20 | 27/01/2016 | De Graafschap | ADO Den Haag | 3-1 | 9.763 | Vd Kerkhof | 0-1 Havenaar, 1-1 Vermeij, 2-1 Tarfi, 3-1 Peters |
| 20 | 27/01/2016 | Excelsior | PSV | 1-3 | 3.700 | Nijhuis | 0-1 De Jong, 0-2 Hendrix, 0-3 Narsingh, 1-3 Bruma (e.d.) |
| 20 | 27/01/2016 | Vitesse | PEC Zwolle | 1-1 | 14.876 | Janssen | 1-0 Van Polen (e.d.), 1-1 Marcellis |
| 20 | 28/01/2016 | Roda JC Kerkrade | FC Utrecht | 1-0 | 13.605 | Makkelie | 1-0 Ngombo |
| 20 | 28/01/2016 | Feyenoord | sc Heerenveen | 1-2 | 47.500 | Van Boekel | 0-1 Veerman, 1-1 Achahbar, 1-2 Van den Berg |
| 21 | 29/01/2016 | Willem II | Heracles Almelo | 0-0 | 13.100 | Janssen | |
| 21 | 30/01/2016 | Vitesse | Excelsior | 0-0 | 20.112 | Manschot | |
| 21 | 30/01/2016 | PEC Zwolle | FC Groningen | 1-3 | 12.125 | Higler | 0-1 Sorloth, 1-1 Lam, 1-2 De Leeuw, 1-3 Hoesen |
| 21 | 30/01/2016 | PSV | De Graafschap | 4-2 | 32.500 | Kuipers | 1-0 De Jong, 2-0 Pröpper, 3-0 Narsingh, 3-1 Van de Pavert, 3-2 Straalman, 4-2 Pereiro |
| 21 | 30/01/2016 | NEC | AZ | 0-3 | 12.130 | Vd Kerkhof | 0-1 Henriksen, 0-2 Jahambakhsh, 0-3 Garcia |
| 21 | 31/01/2016 | Roda JC Kerkrade | Ajax | 2-2 | 17.469 | Gözübüyük | 0-1 Milik, 0-2 El Ghazi, 1-2 Poepon, 2-2 Ngombo |
| 21 | 31/01/2016 | SC Cambuur | sc Heerenveen | 0-1 | 10.000 | Liesveld | 0-1 Zeneli |
| 21 | 31/01/2016 | Feyenoord | ADO Den Haag | 0-2 | 47.500 | Makkelie | 0-1 Jansen, 0-2 Zuiverloon |
| 21 | 31/01/2016 | FC Twente | FC Utrecht | 3-1 | 24.300 | Mulder | 1-0 Uvini, 2-0 El Azzouzi, 3-0 Gutierrez, 3-1 Boymans |
| 22 | 02/02/2016 | Excelsior | Willem II | 0-0 | 3.500 | Vd Graaf | |
| 22 | 03/02/2016 | ADO Den Haag | Roda JC Kerkrade | 2-2 | 11.349 | Mulder | 1-0 Jansen, 1-1 Van Hyfte, 2-1 Derijck, 2-2 Peterson |
| 22 | 03/02/2016 | sc Heerenveen | FC Twente | 1-3 | 23.125 | Higler | 1-0 Veerman, 1-1 Uvini, 1-2 Cabral, 1-3 Ziyech R: Van Aken (Hee) |
| 22 | 03/02/2016 | AZ | Vitesse | 1-0 | 15.006 | Nijhuis | 1-0 Janssen |
| 22 | 03/02/2016 | Heracles Almelo | PEC Zwolle | 2-0 | 10.543 | Van Boekel | 1-0 Bel Hassani, 2-0 Navratil |
| 22 | 04/02/2016 | Ajax | Feyenoord | 2-1 | 51.875 | Blom | 0-1 Toornstra, 1-1 Younes, 2-1 Bazoer |
| 22 | 04/02/2016 | De Graafschap | NEC | 1-1 | 10.123 | Lindhout | 1-0 Driver, 1-1 Ritzmaier; R: Tarfi (Gra) |
| 22 | 04/02/2016 | FC Groningen | SC Cambuur | 2-0 | 20.000 | Makkelie | 1-0 De Leeuw, 2-0 Idrissi |
| 22 | 04/02/2016 | FC Utrecht | PSV | 0-2 | 19.224 | Gözübüyük | 0-1 Arias, 0-2 Van Ginkel |
| 23 | 12/02/2016 | SC Cambuur | FC Utrecht | 0-2 | 9.710 | Nijhuis | 0-1 Van der Maarel, 0-2 Haller |
| 23 | 13/02/2016 | Heracles Almelo | AZ | 3-6 | 11.096 | Kuipers | 0-1 Janssen, 0-2 Henriksen (p), 0-3 V. Overeem, 1-3 Bruns, 1-4 Jahanbakhsh, 2-4 Fledderus, 3-4 Weghorst, 3-5 Bruns (e.d.), 3-6 Rienstra |
| 23 | 13/02/2016 | Willem II | De Graafschap | 0-0 | 12.000 | Van Boekel | |
| 23 | 13/02/2016 | Roda JC Kerkrade | FC Twente | 0-1 | 15.012 | Manschot | 0-1 Ede |
| 23 | 13/02/2016 | Vitesse | sc Heerenveen | 3-0 | 15.234 | Mulder | 1-0 Oliynik, 2-0 en 3-0 (pen) Qazaishvili |
| 23 | 14/02/2016 | FC Groningen | Ajax | 1-2 | 22.500 | Liesveld | 0-1 El Ghazi, 0-2 Schöne (pen), 1-2 Hoesen R: Van der Hoorn (Aja) |
| 23 | 14/02/2016 | PEC Zwolle | Feyenoord | 3-1 | 12.500 | Gözübüyük | 1-0 Veldwijk, 1-1 Van Beek, 2-1 Veldwijk, 3-1 Ehizibue |
| 23 | 14/02/2016 | Excelsior | ADO Den Haag | 2-4 | 3.519 | Janssen | 0-1 Jansen, 1-1 en 2-1 Van Weert, 2-2 en 2-3 Van der Heijden, 2-4 Havenaar |
| 23 | 14/02/2016 | NEC | PSV | 0-3 | 12.353 | Blom | 0-1 De Jong, 0-2 Locadia, 0-3 Van Ginkel |
| 24 | 19/02/2016 | ADO Den Haag | PEC Zwolle | 0-2 | 11.784 | Manschot | 0-1 Dekker, 0-2 Veldwijk |
| 24 | 20/02/2016 | AZ | FC Groningen | 4-1 | 16.325 | Blom | 1-0 Janssen, 2-0 Vlaar, 3-0 Haps, 3-1 De Leeuw (pen), 4-1 Henriksen |
| 24 | 20/02/2016 | sc Heerenveen | NEC | 1-1 | 22.412 | Janssen | 1-0 Veerman, 1-1 Sleegers; R: Van Eijden (NEC) |
| 24 | 20/02/2016 | PSV | Heracles Almelo | 2-0 | 33.400 | Makkelie | 1-0 Pröpper, 2-0 Pereiro (pen) |
| 24 | 20/02/2016 | FC Twente | SC Cambuur | 3-0 | 25.200 | Lindhout | 1-0 Peersman (e.d.), 2-0 Cabral, 3-0 Ziyech (pen) R: Monteiro (Cam) |
| 24 | 21/02/2016 | Feyenoord | Roda JC Kerkrade | 1-1 | 47.500 | Liesveld | 1-0 Kuyt, 1-1 Ngombo |
| 24 | 21/02/2016 | FC Utrecht | Willem II | 2-1 | 17.398 | Vd Kerkhof | 1-0 Boymans, 1-1 Ogbeche (pen), 2-1 Boymans |
| 24 | 21/02/2016 | Ajax | Excelsior | 3-0 | 45.000 | Higler | 1-0 en 2-0 Milik, 3-0 Klaassen |
| 24 | 21/02/2016 | De Graafschap | Vitesse | 2-2 | 12.218 | Gözübüyük | 0-1 Nakamba, 1-1 en 2-1 Vermeij, 2-2 Baker R: Ota (Vit) |
| 25 | 26/02/2016 | Excelsior | NEC | 2-0 | 3.523 | Kuipers | 1-0 en 2-0 Van Weert |
| 25 | 27/02/2016 | FC Twente | FC Groningen | 2-0 | 25.200 | Vd Kerkhof | 1-0 El Azzouzi, 2-0 Cabral |
| 25 | 27/02/2016 | SC Cambuur | PEC Zwolle | 1-0 | 9.775 | Mulder | 1-0 Byrne; R: Bouy (PEC) |
| 25 | 27/02/2016 | PSV | ADO Den Haag | 2-0 | 33.500 | Higler | 1-0 Van Ginkel, 2-0 De Jong |
| 25 | 27/02/2016 | Vitesse | Willem II | 0-1 | 15.987 | Liesveld | 0-1 Ondaan |
| 25 | 28/02/2016 | Heracles Almelo | Roda JC Kerkrade | 0-5 | 10.055 | Vd Graaf | 0-1 Zhukov, 0-2 Van Duinen, 0-3 en 0-4 Poepon, 0-5 Ngombo |
| 25 | 28/02/2016 | De Graafschap | sc Heerenveen | 0-1 | 12.314 | Blom | 0-1 Thorsby |
| 25 | 28/02/2016 | FC Utrecht | Feyenoord | 1-2 | 18.512 | Van Boekel | 1-0 Haller, 1-1 Vilhena, 1-2 Kuyt |
| 25 | 28/02/2016 | Ajax | AZ | 4-1 | 50.000 | Gözübüyük | 1-0 Milik, 2-0 en 3-0 Klaassen, 3-1 Janssen, 4-1 Milik; R: El Ghazi (Aja) |
| 26 | 04/03/2016 | ADO den Haag | FC Twente | 2-1 | 13.128 | Blom | 1-0 Kristensen, 2-0 Derijck (pen), 2-1 Ziyech |
| 26 | 05/03/2016 | PEC Zwolle | De Graafschap | 2-1 | 12.250 | Vd Graaf | 1-0 en 2-0 Nijland, 2-1 Kabasele |
| 26 | 06/03/2016 | AZ | Excelsior | 2-0 | 15.050 | Nijhuis | 1-0 Luckassen, 2-0 Janssen (pen); R: Fischer (Exc) |
| 26 | 05/03/2016 | FC Groningen | PSV | 0-3 | 21.983 | Van Boekel | 0-1 Willems, 0-2 Pröpper, 0-3 Locadia |
| 26 | 05/03/2016 | sc Heerenveen | FC Utrecht | 0-4 | 21.300 | Gözübüyük | 0-1 Ludwig, 0-2 en 0-3 Boymans, 0-4 Kum R: Van den Berg (Hee) |
| 26 | 06/03/2016 | NEC | Heracles Almelo | 1-0 | 12.438 | Manschot | 1-0 Santos |
| 26 | 06/03/2016 | Willem II | Ajax | 0-4 | 14.500 | Makkelie | 0-1 Milik, 0-2 Bazoer, 0-3 Schöne, 0-4 Klaassen |
| 26 | 06/03/2016 | Roda JC Kerkrade | Vitesse | 1-2 | 15.184 | Lindhout | 0-1 Brown, 1-1 Van Duinen, 1-2 Zhang |
| 26 | 06/03/2016 | Feyenoord | SC Cambuur | 3-1 | 47.500 | Higler | 1-0 Toornstra, 1-1 Barto, 2-1 Kuijt, 3-1 Elia |
| 27 | 11/03/2016 | De Graafschap | Roda JC Kerkrade | 3-0 | 12.032 | Janssen | 1-0 El Jebli, 2-0 Pröpper, 3-0 Parzyszek |
| 27 | 12/03/2016 | Willem II | AZ | 0-2 | 14.500 | Vd Graaf | 0-1 en 0-2 (pen) Janssen |
| 27 | 12/03/2016 | PSV | sc Heerenveen | 1-1 | 34.100 | Liesveld | 0-1 Te Vrede, 1-1 De Jong |
| 27 | 12/03/2016 | FC Twente | PEC Zwolle | 2-1 | 27.200 | Makkelie | 0-1 Ehizibue, 1-1 Ziyech, 2-1 Cabral |
| 27 | 12/03/2016 | Excelsior | FC Groningen | 2-1` | 3.500 | Gözübüyük | 1-0 Van Weert, 2-0 Stans (pen), 2-1 De Leeuw |
| 27 | 13/03/2016 | FC Utrecht | ADO Den Haag | 2-2 | 14.164 | Mulder | 1-0 Haller, 2-0 Boymans, 2-1 Bakker, 2-2 Havenaar |
| 27 | 13/03/2016 | Heracles Almelo | SC Cambuur | 3-1 | 10.627 | Kamphuis | 0-1 Byrne, 1-1 Weghorst, 2-1 Gosens, 3-1 Bel Hassani |
| 27 | 13/03/2016 | Vitesse | Feyenoord | 0-2 | 18.834 | Kuipers | 0-1 Kramer, 0-2 Basacikoglu |
| 27 | 13/03/2016 | Ajax | NEC | 2-2 | 42.500 | Van Boekel | 1-0 Milik, 1-1 Foor, 2-1 Van Eijden (e.d.), 2-2 Santos |
| 28 | 18/03/2016 | FC Utrecht | Excelsior | 2-1 | 16.081 | Vd Graaf | 0-1 Kruys, 1-1 (pen) en 2-1 Haller |
| 28 | 19/03/2016 | sc Heerenveen | Heracles Almelo | 0-1 | 24.500 | Lindhout | 0-1 Navratil |
| 28 | 19/03/2016 | Feyenoord | De Graafschap | 2-1 | 47.000 | Nijhuis | 0-1 Pröpper, 1-1 Kramer, 2-1 Elia, 3-1 Bouma (e.d.) |
| 28 | 19/03/2016 | PEC Zwolle | Willem II | 4-1 | 12.185 | Kamphuis | 1-0 Marcellis, 2-0 Menig, 2-1 Falkenburg, 3-1 Veldwijk, 4-1 Nijland |
| 28 | 19/03/2016 | SC Cambuur | Roda JC Kerkrade | 0-1 | 9.762 | Makkelie | 0-1 Van Hyfte |
| 28 | 20/03/2016 | FC Twente | AZ | 2-2 | 25.000 | Van Boekel | 0-1 Janssen, 1-1 Thesker, 1-2 Haye, 2-2 Thesker; R: El Azzouzi (Twe), Wuytens (AZ) |
| 28 | 20/03/2016 | FC Groningen | Vitesse | 0-3 | 17.000 | Janssen | 0-1 Solanke, 0-2 Qazaishvili, 0-3 Solanke |
| 28 | 20/03/2016 | ADO Den Haag | NEC | 1-0 | 10.784 | Vd Kerkhof | 1-0 Malone |
| 28 | 20/03/2016 | PSV | Ajax | 0-2 | 35.000 | Kuipers | 0-1 Milik, 0-2 El Ghazi |
| 29 | 02/04/2016 | Heracles Almelo | FC Utrecht | 1-1 | 12.011 | Vd Kerkhof | 1-0 Navratil, 1-1 Ludwig |
| 29 | 02/04/2016 | De Graafschap | SC Cambuur | 2-2 | 12.600 | Van Boekel | 1-0 Vermeij, 1-1 MacIntosch, 1-2 Van Veen, 2-2 Van de Pavert |
| 29 | 02/04/2016 | AZ | PSV | 2-4 | 17.052 | Gözübüyük | 0-1 Pereiro, 0-2 en 0-3 Van Ginkel, 0-4 Narsingh, 1-4 Van der Linden, 2-4 Tankovic |
| 29 | 02/04/2016 | Feyenoord | Excelsior | 3-0 | 46.500 | Liesveld | 1-0 Kuyt, 2-0 Elia, 3-0 Kuyt |
| 29 | 02/04/2016 | Willem II | FC Twente | 2-3 | 13.110 | Higler | 1-0 Falkenburg, 2-0 Andersen, 2-1 Ziyech, 2-2 Ede, 2-3 Ziyech |
| 29 | 03/04/2016 | NEC | Vitesse | 2-1 | 12.500 | Makkelie | 1-0 Limbombe, 2-0 Dumic, 2-1 Baker |
| 29 | 03/04/2016 | Roda JC Kerkrade | sc Heerenveen | 1-2 | 15.259 | Kuipers | 0-1 Zeneli, 1-1 Van Hyfte, 1-2 Van den Boomen |
| 29 | 03/04/2016 | ADO Den Haag | FC Groningen | 0-1 | 11.891 | Nijhuis | 0-1 Lindgren; R: De Leeuw (Gro) |