Uitslagenmatrix
| ACH | AJA | BEQ | BLA | DOS | ENS | LEE | OOS | RCH | SNE | VIT | VSV | WAG | ZWO | |
| Achilles | * | 1-1 | 0-3 | 0-1 | 1-4 | 0-1 | 0-3 | 0-2 | 0-4 | 1-2 | 2-3 | 2-3 | 0-4 | 0-0 |
| Ajax | 7-0 | * | 3-1 | 2-1 | 3-2 | 1-2 | 7-0 | 2-0 | 2-1 | 4-0 | 2-2 | 6-1 | 2-0 | 2-1 |
| Be Quick | 4-2 | 2-3 | * | 2-0 | 0-3 | 2-3 | 1-0 | 2-0 | 2-2 | 3-0 | 0-3 | 2-1 | 0-1 | 5-0 |
| Blauw Wit | 2-4 | 4-0 | 1-4 | * | 1-1 | 1-1 | 1-2 | 4-2 | 3-2 | 2-2 | 0-0 | 0-0 | 4-1 | 2-2 |
| DOS | 5-2 | 0-1 | 1-1 | 2-2 | * | 2-0 | 4-1 | 5-0 | 1-1 | 2-1 | 6-1 | 2-2 | 3-4 | 3-2 |
| SC Enschede | 2-0 | 1-2 | 1-3 | 3-1 | 3-2 | * | 2-2 | 2-0 | 0-2 | 2-4 | 1-4 | 0-1 | 2-2 | 0-1 |
| Leeuwarden | 6-2 | 4-3 | 1-2 | 3-1 | 5-4 | 0-1 | * | 7-4 | 2-0 | 1-0 | 1-1 | 2-3 | 3-0 | 1-0 |
| Oosterparkers | 4-3 | 0-6 | 0-1 | 3-4 | 2-7 | 0-0 | 1-1 | * | 1-8 | 1-1 | 1-2 | 0-5 | 0-7 | 3-3 |
| RCH | 2-1 | 1-1 | 1-1 | 4-1 | 2-0 | 4-1 | 2-3 | 2-0 | * | 6-2 | 1-1 | 4-2 | 1-2 | 3-1 |
| Sneek | 0-2 | 0-2 | 4-3 | 0-0 | 3-4 | 2-0 | 1-5 | 0-1 | 0-2 | * | 2-6 | 0-0 | 2-1 | 1-2 |
| Vitesse | 2-0 | 3-3 | 0-3 | 3-0 | 1-1 | 1-1 | 1-2 | 6-0 | 3-4 | 3-1 | * | 1-1 | 1-3 | 1-1 |
| VSV | 0-1 | 1-6 | 1-0 | 1-1 | 2-3 | 1-1 | 2-3 | 2-0 | 1-1 | 5-0 | 0-0 | * | 1-1 | 2-2 |
| Wageningen | 0-1 | 1-2 | 4-0 | 1-1 | 5-0 | 7-1 | 3-1 | 2-1 | 2-1 | 9-0 | 1-3 | 0-0 | * | 3-1 |
| Zwolsche Boys | 2-0 | 0-3 | 3-2 | 1-1 | 2-1 | 0-4 | 3-2 | 4-1 | 3-3 | 0-1 | 0-1 | 1-0 | 2-0 | * |
Eindstand
| 1 | Ajax * | 26 | 19 | 4 | 3 | 42 | 76 | 29 | 2.62 |
| 2 | RCH | 26 | 13 | 7 | 6 | 33 | 64 | 36 | 1.77 |
| 3 | Leeuwarden | 26 | 15 | 3 | 8 | 33 | 61 | 49 | 1.24 |
| 4 | Wageningen | 26 | 14 | 4 | 8 | 32 | 64 | 33 | 1.93 |
| 5 | Vitesse | 26 | 11 | 10 | 5 | 32 | 53 | 37 | 1.43 |
| 6 | DOS | 26 | 12 | 6 | 8 | 30 | 68 | 48 | 1.41 |
| 7 | Be Quick (Groningen) | 26 | 13 | 3 | 10 | 29 | 49 | 38 | 1.28 |
| 8 | VSV | 26 | 7 | 11 | 8 | 25 | 38 | 39 | 0.97 |
| 9 | SC Enschede | 26 | 9 | 7 | 10 | 25 | 36 | 45 | 0.80 |
| 10 | Zwolsche Boys | 26 | 8 | 8 | 10 | 24 | 37 | 46 | 0.80 |
| 11 | Blauw Wit | 26 | 6 | 11 | 9 | 23 | 39 | 46 | 0.84 |
| 12 | Sneek | 26 | 6 | 4 | 16 | 16 | 29 | 67 | 0.43 |
| 13 | Achilles | 26 | 4 | 2 | 20 | 10 | 25 | 67 | 0.37 |
| 14 | Oosterparkers ^ | 26 | 3 | 4 | 19 | 10 | 27 | 86 | 0.31 |
Beslissingswedstrijd voor degradatie:
Achilles – Oosterparkers 2-1
Wedstrijden om het landskampioenschap
| 18/05/1952 | Ajax | Hermes DVS | 1-2 | 40.000 | 1-0 Van der Wel, 1-1 Heyster, 1-2 Van Buitenen (pen) |
| 18/05/1952 | Haarlem | Willem II | 2-3 | 1-0 Kors, 1-1 Van Osch, 1-2 De Jong, 1-3 Becx, 2-3 Jacob | |
| 25/05/1952 | Hermes DVS | Haarlem | 2-1 | 40.000 | 0-1 Van Osch, 1-1 en 2-1 Van der Tuyn |
| 25/05/1952 | Willem II | Ajax | 5-2 | 25.000 | 1-0 De Jong, 2-0 Van Roessel (pen), 2-1 Bouwens, 3-1 (pen) en 4-1 Van Roessel, 4-2 Michels, 5-2 Van Roessel |
| 02/06/1952 | Haarlem | Ajax | 2-0 | 1-0 Van Osch, 2-0 Groeneveld | |
| 02/06/1952 | Willem II | Hermes DVS | 3-1 | 25.000 | 1-0 De Jong, 2-0 Becx, 3-0 De Jong, 3-1 Janse |
| 07/06/1952 | Ajax | Haarlem | 2-4 | 25.000 | 0-1 Jacob, 0-2 en 0-3 De Voogd, 1-3 Michels, 1-4 De Voogd, 2-4 Van der Wel |
| 08/06/1952 | Hermes DVS | Willem II | 1-2 | 60.000 | 1-0 Heyster, 1-1 en 1-2 De Jong |
| 15/06/1952 | Ajax | Willem II | 1-2 | 20.000 | 1-0 Van Dijk, 1-1 De Bruyckere, 1-2 Van Roessel |
| 15/06/1952 | Haarlem | Hermes DVS | 1-2 | 8.000 | 1-0 Jacob, 1-1 Heyster, 1-2 Janse |
| 22/06/1952 | Hermes DVS | Ajax | 2-2 | 2.000 | 0-1 Van der Wel, 1-1 Janse, 2-1 eigen doelpunt, 2-2 Van der Wel |
| 22/06/1952 | Willem II | Haarlem | 6-2 | 1-0 De Bruyckere, 2-0 Mommers, 2-1 De Voogd, 2-2 Groeneveld, 3-2 en 4-2 Van Roessel, 5-2 en 6-2 De Jong |
Eindstand
| 1 | Willem II * | 6 | 6 | 0 | 0 | 12 | 21 | 9 | 2.33 |
| 2 | Hermes DVS | 6 | 3 | 1 | 2 | 7 | 10 | 10 | 1.00 |
| 3 | Haarlem | 6 | 2 | 0 | 4 | 4 | 12 | 15 | 0.80 |
| 4 | Ajax | 6 | 0 | 1 | 5 | 1 | 8 | 17 | 0.47 |